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Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor). Catalysis of the reaction: IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate or GMP + diphosphate = guanine + 5-phospho-alpha-D-ribose 1-diphosphate. Catalysis of the transfer of a pentosyl group from one compound (donor) to another (acceptor).

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: hypoxanthine phosphoribosyltransferase activity
Acc: GO:0004422
Aspect: Molecular Function
Desc: Catalysis of the reaction: IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate or GMP + diphosphate = guanine + 5-phospho-alpha-D-ribose 1-diphosphate.
Synonyms:
  • Transphosphoribosidase activity
  • hypoxanthine-guanine phosphoribosyltransferase activity
  • inosinic pyrophosphorylase activity
  • 6-hydroxypurine phosphoribosyltransferase activity
  • GPRT
  • HPRT
  • inosinate pyrophosphorylase activity
  • guanylic pyrophosphorylase activity
  • IMP-GMP pyrophosphorylase activity
  • inosinic acid pyrophosphorylase activity
  • guanosine phosphoribosyltransferase activity
  • IMP pyrophosphorylase activity
  • inosine 5'-phosphate pyrophosphorylase activity
  • guanosine 5'-phosphate pyrophosphorylase activity
  • IMP:diphosphate phospho-D-ribosyltransferase activity
  • 6-mercaptopurine phosphoribosyltransferase activity
  • GMP pyrophosphorylase activity
  • guanine phosphoribosyltransferase activity
  • guanylate pyrophosphorylase activity
  • HGPRTase activity
  • guanine-hypoxanthine phosphoribosyltransferase activity
  • IMP diphosphorylase activity
  • purine-6-thiol phosphoribosyltransferase activity
Proteins in PDR annotated with:
   This term: 27 [Search]
   Term or descendants: 27 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004422 - hypoxanthine phosphoribosyltransferase activity (interactive image map)

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