YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|7437975
Organism:	Synechocystis sp.
Length:	428 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|7437975.

Description	E-value	Query Range	Subject Range
gi\|242257906, gi... - gi\|242257906\|ref\|ZP_04802752.1\| FolC bifunctional protein [Thermoanaerobacter sp. X513], gi\|24223058... gi\|114804496, gi... - gi\|167040832\|ref\|YP_001663817.1\| FolC bifunctional protein [Thermoanaerobacter sp. X514], gi\|1668550...	315.0	[0..2]	[426..5]
gi\|76795846, gi\|... - gi\|76795846\|ref\|ZP_00778217.1\| Folylpolyglutamate synthetase [Thermoanaerobacter ethanolicus ATCC 33... gi\|241903724, gi... - gi\|241903724\|ref\|ZP_04788443.1\| FolC bifunctional protein [Thermoanaerobacter brockii subsp. finnii ...	315.0	[0..2]	[426..5]
gi\|20807265, gi\|... - gi\|20807265\|ref\|NP_622436.1\| folylpolyglutamate synthase [Thermoanaerobacter tengcongensis MB4], gi\|... gi\|20807265 - gi\|20807265\|ref\|NP_622436.1\| Folylpolyglutamate synthase [Thermoanaerobacter tengcongensis MB4]	309.0	[0..2]	[425..8]
gi\|53688657 - gi\|53688657\|ref\|ZP_00111127.2\| COG0285: Folylpolyglutamate synthase [Nostoc punctiforme PCC 73102]	301.0	[0..1]	[422..1]
gi\|51974518, gi\|... - gi\|52141049\|ref\|YP_085780.1\| folylpolyglutamate synthase [Bacillus cereus E33L], gi\|51974518\|gb\|AAU1...	298.0	[0..2]	[428..7]
gi\|67916794, gi\|... - gi\|67916794\|ref\|ZP_00510488.1\| Folylpolyglutamate synthetase [Clostridium thermocellum ATCC 27405], ... gi\|196196835, gi... - gi\|196253747\|ref\|ZP_03152359.1\| FolC bifunctional protein [Clostridium thermocellum DSM 4150], gi\|19...	296.0	[0..3]	[426..6]
gi\|83572311, gi\|... - gi\|83589397\|ref\|YP_429406.1\| FolC bifunctional protein [Moorella thermoacetica ATCC 39073], gi\|83572...	296.0	[0..2]	[426..5]
gi\|110803060, gi... - gi\|110803060\|ref\|YP_699195.1\| FolC bifunctional protein [Clostridium perfringens SM101], gi\|11068356...	296.0	[0..2]	[427..6]
gi\|42739523, gi\|... - gi\|42783594\|ref\|NP_980841.1\| folylpolyglutamate synthase [Bacillus cereus ATCC 10987], gi\|42739523\|g...	296.0	[0..2]	[428..7]
gi\|110800658, gi... - gi\|110800658\|ref\|YP_696598.1\| FolC bifunctional protein [Clostridium perfringens ATCC 13124], gi\|110...	295.0	[0..2]	[427..6]

Back

Predicted Domain #1

Region A:
Residues: [1-428]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDINTLLEPY KTAGVNLGLE RIHGLLAKLG NPQAKVPYVH VGGTNGKGSV CAYLSSVLAE  60
   61 AGYKVGRYTS PHLIDWRERV WLDNRFIDDA SLIGALQQVT AIAPADSSDR PTLFEVFTAA 120
  121 VWLYFAQAEV DIAVMEVGLG GRLDATNVPE PCLLSIITSL SREHWQVLGP TVAHIAREKA 180
  181 GILKAQRPVF LGNIPPEAQA VFQERIAELH CPDYWVTPAI ATEKNGQPWA SWQGFEYPLV 240
  241 LLGDFQLQNS ALAIAALQEL KHQGWDKLTP EVIQRGMGKA VWPGRLQWVD YNGQKILLDG 300
  301 AHNPAAAKAL ANYTHGLVDQ SDNYLPTITW VMGMLSTKEH DQIFQHLLRP GDRLLLVPVP 360
  361 DHDSGDLPTL EQLAWQIMPD LKEVTLFDDC FTALESLEKT NENSEQLTVL CGSLYLVGYF 420
  421 LKRLQSSH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	74.0
Match:	1o5zA
Description:	Crystal structure of Folylpolyglutamate synthase (TM0166) from Thermotoga maritima at 2.10 A resolution
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
acid-amino acid ligase activity	4.03401034724886	bayes_pls_golite062009
tetrahydrofolylpolyglutamate synthase activity	3.94486215528378	bayes_pls_golite062009
ligase activity	3.80574681739772	bayes_pls_golite062009
catalytic activity	2.66037860982128	bayes_pls_golite062009
dihydrofolate synthase activity	2.50201834836027	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	1.96801058335544	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: