YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30258881, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	327 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30258881, gi|....

Description	E-value	Query Range	Subject Range
gi\|25284442 - pir\|\|B83995 branched-chain alpha-keto acid dehydrogenase E1 bfmBAB [imported] - Bacillus halodurans ... gi\|10175383, gi\|... - gi\|15615325\|ref\|NP_243628.1\| branched-chain alpha-keto acid dehydrogenase E1 [Bacillus halodurans C-...	8.0E-92	[1..327]	[1..327]
gi\|56420912, gi\|... - gi\|56420912\|ref\|YP_148230.1\| branched-chain alpha-keto acid dehydrogenase E1 component beta chain (2... gi\|229330700, gi... - gi\|229498329\|ref\|ZP_04392025.1\| Transketolase central region [Geobacillus sp. Y412MC52], gi\|22933070... gi\|220707229, gi... - gi\|221088868\|ref\|ZP_03558394.1\| Transketolase central region [Geobacillus sp. Y412MC61], gi\|22070722...	3.0E-91	[1..327]	[1..327]
ODBB_BACSU - 2-oxoisovalerate dehydrogenase subunit beta OS=Bacillus subtilis (strain 168) GN=bfmBAB PE=1 SV=1 ODBB_BACSU - 2-oxoisovalerate dehydrogenase subunit beta OS=Bacillus subtilis GN=bfmBAB PE=1 SV=1 gi\|221323847 - gi\|221323847\|ref\|ZP_03605141.1\| branched-chain alpha-keto acid dehydrogenase E1 subunit (2-oxoisoval... gi\|221314648 - gi\|221314648\|ref\|ZP_03596453.1\| branched-chain alpha-keto acid dehydrogenase E1 subunit (2-oxoisoval... gi\|221319571 - gi\|221319571\|ref\|ZP_03600865.1\| branched-chain alpha-keto acid dehydrogenase E1 subunit (2-oxoisoval...	7.0E-91	[1..327]	[1..327]
gi\|89086119, gi\|... - gi\|89099273\|ref\|ZP_01172151.1\| branched-chain alpha-keto acid dehydrogenase E1 component beta chain ...	2.0E-90	[1..327]	[1..327]
gi\|113942055, gi... - gi\|159899111\|ref\|YP_001545358.1\| transketolase central region [Herpetosiphon aurantiacus ATCC 23779]...	3.0E-90	[1..327]	[1..327]
gi\|52080942, gi\|... - gi\|52786319\|ref\|YP_092148.1\| BkdAB [Bacillus licheniformis ATCC 14580], gi\|52348821\|gb\|AAU41455.1\| B...	7.0E-90	[1..327]	[1..327]
gi\|85774761, gi\|... - gi\|86158250\|ref\|YP_465035.1\| branched-chain alpha-keto acid dehydrogenase E1 component [Anaeromyxoba...	8.0E-90	[1..327]	[1..324]
gi\|160368554, gi... - gi\|161509745\|ref\|YP_001575404.1\| 2-oxoisovalerate dehydrogenase (acylating) beta subunit [Staphyloco... gi\|262049102\|ref... - branched-chain alpha-keto acid dehydrogenase E1 [Staphylococcus aureus D30] gi\|284024576\|ref... - 2-oxoisovalerate dehydrogenase, E1 component, beta subunit [Staphylococcus aureus subsp. aureus 132] gi\|282924765\|ref... - 2-oxoisovalerate dehydrogenase E1 component, beta subunit [Staphylococcus aureus A9765] gi\|262051183\|ref... - branched-chain alpha-keto acid dehydrogenase E1 [Staphylococcus aureus 930918-3] gi\|57284659, gi\|... - gi\|57650473\|ref\|YP_186402.1\| 2-oxoisovalerate dehydrogenase, E1 component, beta subunit [Staphylococ... gi\|151221634, gi... - gi\|151221634\|ref\|YP_001332456.1\| 2-oxoisovalerate dehydrogenase, E1 component, beta subunit [Staphyl... gi\|87126110\|gb\|A... - 2-oxoisovalerate dehydrogenase, E1 component, beta subunit [Staphylococcus aureus subsp. aureus USA3... gi\|258451174\|ref... - 2-oxoisovalerate dehydrogenase, beta subunit [Staphylococcus aureus A5948] gi\|88195323, gi\|... - gi\|88195323\|ref\|YP_500127.1\| 2-oxoisovalerate dehydrogenase, E1 component, beta subunit, putative [S... gi\|87160136, gi\|... - gi\|87160136\|ref\|YP_494161.1\| 2-oxoisovalerate dehydrogenase, E1 component, beta subunit [Staphylococ...	1.0E-88	[1..327]	[1..327]
gi\|56964215, gi\|... - gi\|56964215\|ref\|YP_175946.1\| branched-chain alpha-keto acid dehydrogenase E1 component beta chain [B...	2.0E-88	[1..327]	[1..327]
gi\|258446762\|ref... - branched-chain alpha-keto acid dehydrogenase E1 [Staphylococcus aureus A6300] gi\|258453493\|ref... - branched-chain alpha-keto acid dehydrogenase E1 [Staphylococcus aureus A5937] gi\|21283198, gi\|... - gi\|21283198\|ref\|NP_646286.1\| branched-chain alpha-keto acid dehydrogenase E1 [Staphylococcus aureus ... gi\|49244796, gi\|... - gi\|49486353\|ref\|YP_043574.1\| 2-oxoisovalerate dehydrogenase beta subunit [Staphylococcus aureus subs... gi\|25284447 - pir\|\|D89931 branched-chain alpha-keto acid dehydrogenase E1 [imported] - Staphylococcus aureus (stra... gi\|156979835, gi... - gi\|156979835\|ref\|YP_001442094.1\| branched-chain alpha-keto acid dehydrogenase E1 [Staphylococcus aur... gi\|258443555\|ref... - branched-chain alpha-keto acid dehydrogenase E1 [Staphylococcus aureus A8115] gi\|269203146\|ref... - 2-oxoisovalerate dehydrogenase, E1 component, beta subunit [Staphylococcus aureus subsp. aureus ED98... gi\|15924506, gi\|... - gi\|15924506\|ref\|NP_372040.1\| branched-chain alpha-keto acid dehydrogenase E1 [Staphylococcus aureus ... gi\|15927097, gi\|... - gi\|15927097\|ref\|NP_374630.1\| branched-chain alpha-keto acid dehydrogenase E1 [Staphylococcus aureus ... gi\|258437349\|ref... - branched-chain alpha-keto acid dehydrogenase E1 [Staphylococcus aureus A9299] gi\|251814513, gi... - gi\|251814513\|ref\|ZP_04828986.1\| branched-chain alpha-keto acid dehydrogenase E1 [Staphylococcus aure... gi\|258448676\|ref... - branched-chain alpha-keto acid dehydrogenase E1 [Staphylococcus aureus A6224] gi\|255006303 - gi\|255006303\|ref\|ZP_05144904.2\| branched-chain alpha-keto acid dehydrogenase E1 [Staphylococcus aure... gi\|282893018\|ref... - 2-oxoisovalerate dehydrogenase E1 component, beta subunit [Staphylococcus aureus A8117] gi\|253314886 - gi\|253314886\|ref\|ZP_04838099.1\| branched-chain alpha-keto acid dehydrogenase E1 [Staphylococcus aure... gi\|258411107\|ref... - branched-chain alpha-keto acid dehydrogenase subunit E1 [Staphylococcus aureus A9763] gi\|282928988\|ref... - 2-oxoisovalerate dehydrogenase E1 component, beta subunit [Staphylococcus aureus A10102]	3.0E-88	[1..327]	[1..327]

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Predicted Domain #1

Region A:
Residues: [1-327]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVMSYIDAI TLAMREEMER DEKVFVLGED VGKKGGVFKA THGLYDQFGE DRALDTPLAE  60
   61 SAIAGVAIGA AMYGMRPIAE MQFADFIMPA VNQIVSEAAK IRYRSNNDWT CPITVRAPFG 120
  121 GGVHGALYHS QSVEAMFANQ PGLKIVIPST PYDAKGLLKA AIRDEDPVLF FEHKRAYRLI 180
  181 KGEVPEDDYV LPIGKADVKR EGDDITVITY GLCVHFALQA AEKLAQDGIS AHILDLRTVY 240
  241 PLDKEAIIEA ASKTGKVLLV TEDNKEGSIM SEVAAIIAEN CLFDLDAPIA RLAGPDVPAM 300
  301 PYAPTMEKFF MVNPDKVEKA MRELAEF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	84.221849
Match:	1w85B
Description:	The crystal structure of pyruvate deydrogenase E1 bound to the peripheral subunit binding domain of E2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
pyruvate dehydrogenase activity	11.3856674722026	bayes_pls_golite062009
pyruvate dehydrogenase (acetyl-transferring) activity	11.0549577473177	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	10.8180381281695	bayes_pls_golite062009
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity	7.00951713446616	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors	4.89064211833637	bayes_pls_golite062009
acetolactate synthase activity	4.51986503762195	bayes_pls_golite062009
alpha-ketoacid dehydrogenase activity	2.61614462349133	bayes_pls_golite062009
transferase activity, transferring aldehyde or ketonic groups	2.21959520697519	bayes_pls_golite062009
transketolase activity	2.20554088536433	bayes_pls_golite062009
transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer	0.667418924427388	bayes_pls_golite062009
binding	0.551586872853971	bayes_pls_golite062009
catalytic activity	0.545407789079971	bayes_pls_golite062009
oxidoreductase activity	0.281475773435032	bayes_pls_golite062009
pyruvate decarboxylase activity	0.198062360371269	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: