YRC Public Data Repository - Protein Structure Prediction

Protein:	MTNA_PSEAB
Organism:	Pseudomonas aeruginosa UCBPP-PA14
Length:	358 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MTNA_PSEAB.

Description	E-value	Query Range	Subject Range
gi\|49086588 - gi\|49086588\|gb\|AAT51365.1\| PA3169 [synthetic construct]	0.0	[1..358]	[1..358]
MTNA_THEMA - Methylthioribose-1-phosphate isomerase OS=Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 /... MTNA_THEMA - Methylthioribose-1-phosphate isomerase OS=Thermotoga maritima GN=mtnA PE=1 SV=1	0.0	[7..353]	[1..342]
MTNA_PSEA7 - Methylthioribose-1-phosphate isomerase OS=Pseudomonas aeruginosa (strain PA7) GN=mtnA PE=3 SV=1	0.0	[1..358]	[1..358]
MTNA_PSE14 - Methylthioribose-1-phosphate isomerase OS=Pseudomonas savastanoi pv. phaseolicola (strain 1448A / Ra...	0.0	[1..358]	[1..358]
MTNA_AZOVD - Methylthioribose-1-phosphate isomerase OS=Azotobacter vinelandii (strain DJ / ATCC BAA-1303) GN=mtnA... gi\|23105300, gi\|... - gi\|67158245\|ref\|ZP_00419295.1\| Initiation factor 2B [Azotobacter vinelandii AvOP], ref\|ZP_00091758.1...	0.0	[1..358]	[1..358]
gi\|23472134, gi\|... - gi\|66046877\|ref\|YP_236718.1\| methylthioribose-1-phosphate isomerase [Pseudomonas syringae pv. syring...	0.0	[1..358]	[8..365]
MTNA_CALS8 - Methylthioribose-1-phosphate isomerase OS=Caldicellulosiruptor saccharolyticus (strain ATCC 43494 / ...	0.0	[11..354]	[1..342]
MTNA_GEOMG - Methylthioribose-1-phosphate isomerase OS=Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM...	0.0	[11..353]	[3..345]
MTNA_PSEPF - Methylthioribose-1-phosphate isomerase OS=Pseudomonas fluorescens (strain Pf0-1) GN=mtnA PE=3 SV=1	0.0	[1..358]	[1..358]
MTNA_GEOSL - Methylthioribose-1-phosphate isomerase OS=Geobacter sulfurreducens GN=mtnA PE=3 SV=1 MTNA_GEOSL - Methylthioribose-1-phosphate isomerase OS=Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / ...	0.0	[11..351]	[3..343]

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Predicted Domain #1

Region A:
Residues: [1-358]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRERLLAAER VKAIEWRDGT LRLLDQRLLP QEEVWLEHES AAEVAKAIRD MVVRGAPAIG  60
   61 ISAAYGIVLG ARARLAQGGD WRAALEEDFR LLADSRPTAV NLFWALNRMR DRLERMKEGD 120
  121 QPLAVLEAEA ISIHESDREA NLTMAQLGME LIRKQQGSPQ NILTHCNTGA LATGGFGTAL 180
  181 GVIRAAHLEG LVNRIYADET RPWLQGSRLT AWELANEGIP VSLNVDSAAA HLMKTENITW 240
  241 VIVGADRITA NGDVANKIGT YQLAVNAMHH GVRFMVVAPS STIDMNLESG EDIPIEERDG 300
  301 RELLEIGGRR VAAEVDAYNP VFDVTPADLI DAIVTERGVV ERPDAERMAA LMSRKRLH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	116.0
Match:	1t9kA
Description:	X-ray crystal structure of aIF-2B alpha subunit-related translation initiation factor [Thermotoga maritima]
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
translation initiation factor activity	10.1099993541596	bayes_pls_golite062009
translation regulator activity	5.74669335554405	bayes_pls_golite062009
nucleic acid binding	1.56128901279222	bayes_pls_golite062009
transferase activity, transferring sulfur-containing groups	1.40526340076289	bayes_pls_golite062009
catalytic activity	1.31732715713197	bayes_pls_golite062009
translation factor activity, nucleic acid binding	1.09424756417577	bayes_pls_golite062009
transcription regulator activity	0.987801998446038	bayes_pls_golite062009
binding	0.946249883212717	bayes_pls_golite062009
DNA binding	0.730721872216867	bayes_pls_golite062009
deaminase activity	0.518630450774121	bayes_pls_golite062009
S-methyl-5-thioribose-1-phosphate isomerase activity	0.511292518421556	bayes_pls_golite062009
transcription factor activity	0.195177143221873	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: