YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30260077, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	224 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30260077, gi|....

Description	E-value	Query Range	Subject Range
gi\|49331990, gi\|... - gi\|49480434\|ref\|YP_039367.1\| membrane protein; metalloprotease [Bacillus thuringiensis serovar konku...	1.0E-37	[1..224]	[1..224]
gi\|51973658, gi\|... - gi\|52140189\|ref\|YP_086643.1\| membrane protein; metalloprotease [Bacillus cereus E33L], gi\|51973658\|g...	2.0E-37	[1..224]	[1..224]
gi\|228771054, gi... - gi\|228988603\|ref\|ZP_04148689.1\| Metal-dependent protease [Bacillus thuringiensis serovar tochigiensi... gi\|47552977, gi\|... - gi\|47570362\|ref\|ZP_00241005.1\| membrane metalloprotease [Bacillus cereus G9241], gi\|47552977\|gb\|EAL1...	3.0E-37	[1..224]	[1..224]
gi\|42784551, gi\|... - gi\|42784551\|ref\|NP_981798.1\| hypothetical protein BCE_5506 [Bacillus cereus ATCC 10987], gi\|42740483...	9.0E-37	[1..224]	[1..224]
gi\|228903855, gi... - gi\|228903855\|ref\|ZP_04067970.1\| Metal-dependent protease [Bacillus thuringiensis IBL 4222], gi\|22885... gi\|218160489, gi... - gi\|218232532\|ref\|YP_002370153.1\| peptidase, M50 family [Bacillus cereus B4264], gi\|218160489\|gb\|ACK6... gi\|229051047, gi... - gi\|229051047\|ref\|ZP_04194594.1\| Metal-dependent protease [Bacillus cereus AH676], gi\|228722258\|gb\|EE... gi\|75758543, gi\|... - gi\|75758543\|ref\|ZP_00738663.1\| Membrane endopeptidase, M50 family [Bacillus thuringiensis serovar is... gi\|228791215, gi... - gi\|228968509\|ref\|ZP_04129497.1\| Metal-dependent protease [Bacillus thuringiensis serovar sotto str. ... gi\|229147916, gi... - gi\|229147916\|ref\|ZP_04276257.1\| Metal-dependent protease [Bacillus cereus BDRD-ST24], gi\|228635566\|g... gi\|228670623, gi... - gi\|229112789\|ref\|ZP_04242321.1\| Metal-dependent protease [Bacillus cereus Rock1-15], gi\|228670623\|gb... gi\|218900504, gi... - gi\|218900504\|ref\|YP_002448915.1\| peptidase, M50 family [Bacillus cereus G9842], gi\|218542791\|gb\|ACK9...	1.0E-36	[1..224]	[1..224]
gi\|228647270, gi... - gi\|229136192\|ref\|ZP_04264944.1\| Metal-dependent protease [Bacillus cereus BDRD-ST196], gi\|228647270\|... gi\|229170081, gi... - gi\|229170081\|ref\|ZP_04297772.1\| Metal-dependent protease [Bacillus cereus AH621], gi\|228613428\|gb\|EE... gi\|89205922, gi\|... - gi\|89205922\|ref\|ZP_01184487.1\| Peptidase M50 [Bacillus weihenstephanensis KBAB4], gi\|89156148\|gb\|EAR...	3.0E-36	[1..223]	[1..223]
gi\|89201464, gi\|... - gi\|89201464\|ref\|ZP_01180204.1\| Peptidase M50 [Bacillus cereus subsp. cytotoxis NVH 391-98], gi\|89150...	7.0E-36	[1..224]	[1..224]
gi\|65317355, gi\|... - gi\|65317355\|ref\|ZP_00390314.1\| COG1994: Zn-dependent proteases [Bacillus anthracis str. A2012], ref\|...	9.0E-36	[1..203]	[1..203]
gi\|30023407, gi\|... - gi\|30023407\|ref\|NP_835038.1\| membrane metalloprotease [Bacillus cereus ATCC 14579], gi\|29898968\|gb\|A...	4.0E-33	[12..224]	[4..216]
gi\|73540804, gi\|... - gi\|73540804\|ref\|YP_295324.1\| peptidase M50 [Ralstonia eutropha JMP134], gi\|72118217\|gb\|AAZ60480.1\| P...	1.0E-30	[6..220]	[3..220]

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Predicted Domain #1

Region A:
Residues: [1-224]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDQLFRYPLH QIPLVAMAII IALSVHEFAH AYVAYKFGDD TAKRQGRLTL SPMAHLDPIG  60
   61 MIAVLILGFG WARPVPVNPY NFKRPRLAGI LVSIAGPISN LILSAIGLII WYSLLTFGVL 120
  121 DSIPFAVADT LAQFFQIFIM LNIVLLVFNL LPIPPLDGYR VVEDLAPTNI RAKMTQYEKY 180
  181 GAIALLILVI TPLSNYTIQP IFNVVIPYVF AFLNSIIAPI FGLL

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	0.981
Match:	1fj3A
Description:	Thermolysin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
peptidase activity	3.81880522033724	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	3.48431287054013	bayes_pls_golite062009
metallopeptidase activity	2.75562937091394	bayes_pls_golite062009
hydrolase activity	2.41407803761037	bayes_pls_golite062009
endopeptidase activity	2.3107572739426	bayes_pls_golite062009
metalloendopeptidase activity	2.08575905138297	bayes_pls_golite062009
catalytic activity	0.843772148375291	bayes_pls_golite062009
binding	0.756257487145456	bayes_pls_golite062009
protein binding	0.50959283149761	bayes_pls_golite062009
exopeptidase activity	0.160545038651425	bayes_pls_golite062009
protein complex binding	0.0156240732951098	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: