YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30263872, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	401 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30263872, gi|....

Description	E-value	Query Range	Subject Range
gi\|15978163, gi\|... - gi\|16120401\|ref\|NP_403714.1\| phosphopantothenoylcysteine synthase/decarboxylase [Yersinia pestis CO9... gi\|150260888, gi... - gi\|150260888\|ref\|ZP_01917616.1\| DNA/pantothenate metabolism flavoprotein [Yersinia pestis CA88-4125]... gi\|51594403, gi\|... - gi\|51594403\|ref\|YP_068594.1\| phosphopantothenoylcysteine synthase/decarboxylase [Yersinia pseudotube... Q66GD7\|Q66GD7_YERPS - DNA/pantothenate metabolism flavoprotein - Yersinia pseudotuberculosis gi\|165936230, gi... - gi\|165936230\|ref\|ZP_02224799.1\| phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cyste... gi\|45434769, gi\|... - gi\|45439914\|ref\|NP_991453.1\| phosphopantothenoylcysteine synthase/decarboxylase [Yersinia pestis bio... gi\|25322282 - pir\|\|AI0006 DNA/pantothenate metabolism flavoprotein [imported] - Yersinia pestis (strain CO92)	0.0	[2..399]	[5..402]
gi\|77630874 - gi\|77630874\|ref\|ZP_00793460.1\| COG0452: Phosphopantothenoylcysteine synthetase/decarboxylase [Yersin...	0.0	[2..399]	[5..402]
gi\|22124013, gi\|... - gi\|22124013\|ref\|NP_667436.1\| phosphopantothenoylcysteine synthase/decarboxylase [Yersinia pestis KIM... gi\|145212793, gi... - gi\|145601097\|ref\|YP_001165173.1\| bifunctional phosphopantothenoylcysteine decarboxylase/phosphopanto... gi\|165926067, gi... - gi\|165926067\|ref\|ZP_02221899.1\| phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cyste... gi\|166213762, gi... - gi\|166213762\|ref\|ZP_02239797.1\| phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cyste... gi\|166011425, gi... - gi\|166011425\|ref\|ZP_02232323.1\| phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cyste... gi\|167418905, gi... - gi\|167418905\|ref\|ZP_02310658.1\| phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cyste... gi\|167402115, gi... - gi\|167402115\|ref\|ZP_02307592.1\| phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cyste... gi\|186893391, gi... - gi\|186893391\|ref\|YP_001870503.1\| phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cyst... gi\|89103898 - gi\|89103898\|ref\|ZP_01176458.1\| COG0452: Phosphopantothenoylcysteine synthetase/decarboxylase [Yersin... gi\|167426675, gi... - gi\|167426675\|ref\|ZP_02318428.1\| phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cyste... gi\|108809485, gi... - gi\|108809485\|ref\|YP_653401.1\| bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothe... gi\|77634073, gi\|... - gi\|77634073\|ref\|ZP_00796182.1\| COG0452: Phosphopantothenoylcysteine synthetase/decarboxylase [Yersin... gi\|108813962, gi... - gi\|108813962\|ref\|YP_649729.1\| bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothe...	0.0	[2..399]	[43..440]
gi\|114564979, gi... - gi\|69951298\|ref\|ZP_00639039.1\| DNA/pantothenate metabolism flavoprotein [Shewanella frigidimarina NC...	0.0	[1..399]	[4..400]
gi\|68177696, gi\|... - gi\|95929445\|ref\|ZP_01312188.1\| phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cystei...	0.0	[1..400]	[1..399]
gi\|56419704, gi\|... - gi\|56419704\|ref\|YP_147022.1\| pantothenate metabolism flavoprotein [Geobacillus kaustophilus HTA426],...	0.0	[1..392]	[1..393]
gi\|152024987, gi... - gi\|89203169\|ref\|ZP_01181863.1\| DNA/pantothenate metabolism flavoprotein [Bacillus cereus subsp. cyto...	0.0	[1..399]	[1..399]
gi\|22777187, gi\|... - gi\|23098959\|ref\|NP_692425.1\| pantothenate metabolism [Oceanobacillus iheyensis HTE831], gi\|22777187\|...	0.0	[1..399]	[1..400]
gi\|89334921, gi\|... - gi\|89895473\|ref\|YP_518960.1\| hypothetical protein DSY2727 [Desulfitobacterium hafniense Y51], gi\|893... gi\|219669909, gi... - gi\|68205307\|ref\|ZP_00557511.1\| DNA/pantothenate metabolism flavoprotein [Desulfitobacterium hafniens...	0.0	[1..400]	[1..400]
gi\|48868497, gi\|... - gi\|68249541\|ref\|YP_248653.1\| bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothen...	0.0	[2..398]	[3..398]

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Predicted Domain #1

Region A:
Residues: [1-185]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLKGKKILLC VTGGIAVFKA AALTSKLTQA GAIVKVMMSE SAVKFVTPLT FQALSRHDVY  60
   61 TDTFDEKDSA VIAHIDLADW ADVVLVAPAT ANCIGKLANG IADDMITTTL LATTAPVWIA 120
  121 PAMNVHMYEN KIVQKNMMTL KTLGYTFIEP GEGFLACGYV AKGRLEEPEA IIARLEEAFS 180
  181 EQKPL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	49.221849
Match:	1qzuA
Description:	crystal structure of human phosphopantothenoylcysteine decarboxylase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
phosphopantothenoylcysteine decarboxylase activity	3.86093811191169	bayes_pls_golite062009
phosphopantothenate--cysteine ligase activity	2.64345867885176	bayes_pls_golite062009
carboxy-lyase activity	1.79168084682693	bayes_pls_golite062009
catalytic activity	1.51672397362026	bayes_pls_golite062009
carbon-carbon lyase activity	1.03827559540394	bayes_pls_golite062009
binding	0.299141917010304	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [186-401]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QGKRILITAG PTREKIDPVR FMTNFSSGKM GYAIAEVAVN LGAEVILVSG PTALNPPLHV  60
   61 TTVQVESAQD MLEAVIQHYQ NVDVVIKTAA VADYRPKYVH DNKMKKKNGD AVIELERTVD 120
  121 ILKTLGEMKD KQLLIGFAAE TTNVEEYATK KLREKNANMI VANDVKAQGA GFGTDTNIVT 180
  181 MYRKDGEVIE LPLLTKKEVA REILKQIEMM LEDDRL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	69.0
Match:	1u7uA
Description:	Phosphopantothenoylcysteine synthetase from E. coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
phosphopantothenate--cysteine ligase activity	5.69075768451173	bayes_pls_golite062009
phosphopantothenoylcysteine decarboxylase activity	5.47152792211468	bayes_pls_golite062009
catalytic activity	1.32370671504792	bayes_pls_golite062009
carboxy-lyase activity	1.28899846789805	bayes_pls_golite062009
ligase activity	0.615843055306698	bayes_pls_golite062009
carbon-carbon lyase activity	0.53776941010038	bayes_pls_golite062009
acid-amino acid ligase activity	0.529888965129474	bayes_pls_golite062009
binding	0.396515598353762	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	0.133284065682966	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions: