YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30257919, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	425 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30257919, gi|....

Description	E-value	Query Range	Subject Range
gi\|22125253, gi\|... - gi\|22125253\|ref\|NP_668676.1\| histidyl-tRNA synthetase [Yersinia pestis KIM], gi\|21958124\|gb\|AAM84927...	8.0E-62	[3..425]	[5..419]
SYH_YERPS - Histidine--tRNA ligase OS=Yersinia pseudotuberculosis serotype I (strain IP32953) GN=hisS PE=3 SV=1 gi\|45442516, gi\|... - gi\|45442516\|ref\|NP_994055.1\| histidyl-tRNA synthetase [Yersinia pestis biovar Microtus str. 91001], ... gi\|218929938, gi... - gi\|218929938\|ref\|YP_002347813.1\| histidyl-tRNA synthetase [Yersinia pestis CO92], gi\|16123070\|ref\|NP... SYH_YERPG - Histidine--tRNA ligase OS=Yersinia pestis bv. Antiqua (strain Angola) GN=hisS PE=3 SV=1 SYH_YERPY - Histidine--tRNA ligase OS=Yersinia pseudotuberculosis serotype O:3 (strain YPIII) GN=hisS PE=3 SV=1 gi\|167057987, gi... - gi\|167423817\|ref\|ZP_02315570.1\| histidyl-tRNA synthetase [Yersinia pestis biovar Mediaevalis str. K1... SYH_YERPE - Histidine--tRNA ligase OS=Yersinia pestis GN=hisS PE=3 SV=1 SYH_YERPB - Histidine--tRNA ligase OS=Yersinia pseudotuberculosis serotype IB (strain PB1/+) GN=hisS PE=3 SV=1 gi\|149291751, gi... - gi\|149365338\|ref\|ZP_01887373.1\| histidyl-tRNA synthetase [Yersinia pestis CA88-4125], gi\|149291751\|g... gi\|165922241, gi... - gi\|165926037\|ref\|ZP_02221869.1\| histidyl-tRNA synthetase [Yersinia pestis biovar Orientalis str. F19... SYH_YERPP - Histidine--tRNA ligase OS=Yersinia pestis (strain Pestoides F) GN=hisS PE=3 SV=1 gi\|166206520, gi... - gi\|166212589\|ref\|ZP_02238624.1\| histidyl-tRNA synthetase [Yersinia pestis biovar Antiqua str. B42003... gi\|229694823, gi... - gi\|229838457\|ref\|ZP_04458616.1\| histidyl tRNA synthetase [Yersinia pestis biovar Orientalis str. PEX... gi\|165992986, gi... - gi\|166008604\|ref\|ZP_02229502.1\| histidyl-tRNA synthetase [Yersinia pestis biovar Antiqua str. E19790... gi\|229895159, gi... - gi\|229895159\|ref\|ZP_04510335.1\| histidyl tRNA synthetase [Yersinia pestis Pestoides A], gi\|229701921... gi\|166960881, gi... - gi\|167421392\|ref\|ZP_02313145.1\| histidyl-tRNA synthetase [Yersinia pestis biovar Orientalis str. MG0... gi\|229899024, gi... - gi\|229899024\|ref\|ZP_04514168.1\| histidyl tRNA synthetase [Yersinia pestis biovar Orientalis str. Ind... gi\|167399422, gi... - gi\|167399422\|ref\|ZP_02304946.1\| histidyl-tRNA synthetase [Yersinia pestis biovar Antiqua str. UG05-0... SYH_YERPN - Histidine--tRNA ligase OS=Yersinia pestis bv. Antiqua (strain Nepal516) GN=hisS PE=3 SV=1 SYH_YERPS - Histidine--tRNA ligase OS=Yersinia pseudotuberculosis GN=hisS PE=3 SV=1 gi\|165915025, gi... - gi\|89103477\|ref\|ZP_01176053.1\| COG0124: Histidyl-tRNA synthetase [Yersinia pestis biovar Orientalis ... SYH_YERPA - Histidine--tRNA ligase OS=Yersinia pestis bv. Antiqua (strain Antiqua) GN=hisS PE=3 SV=1	9.0E-62	[3..425]	[5..419]
SYH_YERP3 - Histidine--tRNA ligase OS=Yersinia pseudotuberculosis serotype O:1b (strain IP 31758) GN=hisS PE=3 S...	1.0E-61	[3..425]	[5..419]
SYH_PHOPR - Histidine--tRNA ligase OS=Photobacterium profundum GN=hisS PE=3 SV=1 SYH_PHOPR - Histidine--tRNA ligase OS=Photobacterium profundum (strain SS9) GN=hisS PE=3 SV=1	2.0E-61	[2..425]	[4..418]
SYH_ECOL6 - (P60907) Histidyl-tRNA synthetase (EC 6.1.1.21) (Histidine--tRNA ligase) (HisRS) SYH_ECOLI - (P60906) Histidyl-tRNA synthetase (EC 6.1.1.21) (Histidine--tRNA ligase) (HisRS) SYH_ECO57 - (P60908) Histidyl-tRNA synthetase (EC 6.1.1.21) (Histidine--tRNA ligase) (HisRS)	3.0E-61	[3..425]	[4..418]
gi\|86608180 - gi\|86608180\|ref\|YP_476942.1\| histidyl-tRNA synthetase [Cyanobacteria bacterium Yellowstone B-Prime] gi\|86556722, gi\|... - gi\|86608180\|ref\|YP_476942.1\| histidyl-tRNA synthetase [Synechococcus sp. JA-2-3B'a(2-13)], gi\|865567...	3.0E-61	[3..425]	[4..415]
gi\|229344539, gi... - gi\|229517824\|ref\|ZP_04407268.1\| histidyl-tRNA synthetase [Vibrio cholerae RC9], gi\|229344539\|gb\|EEO0... gi\|229349994, gi... - gi\|229513101\|ref\|ZP_04402567.1\| histidyl-tRNA synthetase [Vibrio cholerae TMA 21], gi\|229349994\|gb\|E... gi\|229333884, gi... - gi\|229530110\|ref\|ZP_04419500.1\| histidyl-tRNA synthetase [Vibrio cholerae 12129(1)], gi\|229333884\|gb... gi\|229339781, gi... - gi\|229523418\|ref\|ZP_04412825.1\| histidyl-tRNA synthetase [Vibrio cholerae TM 11079-80], gi\|229339781... gi\|229608644, gi... - gi\|229608644\|ref\|YP_002879292.1\| histidyl-tRNA synthetase [Vibrio cholerae MJ-1236], gi\|229371299\|gb... SYH_VIBCH - Histidine--tRNA ligase OS=Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) GN=h... gi\|121546710, gi... - gi\|121591433\|ref\|ZP_01678711.1\| histidyl-tRNA synthetase [Vibrio cholerae 2740-80], gi\|121546710\|gb\|... gi\|124114378, gi... - gi\|153216233\|ref\|ZP_01950333.1\| histidyl-tRNA synthetase [Vibrio cholerae 1587], gi\|124114378\|gb\|EAY... gi\|121726005, gi... - gi\|121726005\|ref\|ZP_01679304.1\| histidyl-tRNA synthetase [Vibrio cholerae V52], gi\|121631487\|gb\|EAX6... gi\|254222188, gi... - gi\|254222188\|ref\|ZP_04916061.1\| histidyl-tRNA synthetase [Vibrio cholerae RC385], gi\|194536562\|ref\|Y... gi\|153800575, gi... - gi\|153800575\|ref\|ZP_01955161.1\| histidyl-tRNA synthetase [Vibrio cholerae MZO-3], gi\|124123864\|gb\|EA... gi\|148876236, gi... - gi\|153828282\|ref\|ZP_01980949.1\| histidyl-tRNA synthetase [Vibrio cholerae 623-39], gi\|148876236\|gb\|E... gi\|124120255, gi... - gi\|153220691\|ref\|ZP_01951802.1\| histidyl-tRNA synthetase [Vibrio cholerae MAK 757], gi\|124120255\|gb\|... gi\|149741838, gi... - gi\|153824620\|ref\|ZP_01977287.1\| histidyl-tRNA synthetase [Vibrio cholerae MZO-2], gi\|149741838\|gb\|ED... gi\|153817271, gi... - gi\|153817271\|ref\|ZP_01969938.1\| histidyl-tRNA synthetase [Vibrio cholerae NCTC 8457], gi\|126512187\|g... SYH_VIBC3 - Histidine--tRNA ligase OS=Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O39... SYH_VIBCH - Histidine--tRNA ligase OS=Vibrio cholerae GN=hisS PE=3 SV=1 gi\|254843602, gi... - gi\|254847897\|ref\|ZP_05237247.1\| histidyl-tRNA synthetase [Vibrio cholerae MO10], gi\|254843602\|gb\|EET... gi\|153822725, gi... - gi\|229510702\|ref\|ZP_04400181.1\| histidyl-tRNA synthetase [Vibrio cholerae B33], gi\|229350667\|gb\|EEO1... gi\|229357849, gi... - gi\|229505626\|ref\|ZP_04395136.1\| histidyl-tRNA synthetase [Vibrio cholerae BX 330286], gi\|229357849\|g... SYH_VIBCM - Histidine--tRNA ligase OS=Vibrio cholerae serotype O1 (strain M66-2) GN=hisS PE=3 SV=1	4.0E-61	[3..425]	[5..418]
SYH_MOOTA - Histidine--tRNA ligase OS=Moorella thermoacetica (strain ATCC 39073) GN=hisS PE=3 SV=1	4.0E-61	[1..424]	[1..414]
gi\|91190081, gi\|... - gi\|91225138\|ref\|ZP_01260360.1\| histidyl-tRNA synthetase [Vibrio alginolyticus 12G01], gi\|91190081\|gb...	4.0E-61	[3..425]	[5..418]
gi\|89051523, gi\|... - gi\|89072703\|ref\|ZP_01159268.1\| histidyl-tRNA synthetase [Photobacterium sp. SKA34], gi\|89051523\|gb\|E...	5.0E-61	[2..425]	[4..418]

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Predicted Domain #1

Region A:
Residues: [1-425]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEIRNVKGTK DYLPEEQVLR SKIKRACEDT FERYGCKPLE TPTLNMYELM SYKYGGGDEI  60
   61 LKEIYTLQDQ GKRDLALRYD LTIPFAKVVA MNPNIRLPFK RYEIGKVFRD GPIKQGRFRE 120
  121 FIQCDVDIVG VESVMAEAEL MSMAFELFQT LNLEVTIQYN NRKLLNGILQ AINIPTELTS 180
  181 DVILSLDKIE KIGIDGVRKD VLERGISEEM ADTICNTVLS CLQLSIADFK EAFNNPLVAD 240
  241 GVNELQQLQQ YLIALGINEN TIFNPFLARG LTMYTGTVYE IFLKDGSITS SIGSGGRYDN 300
  301 IIGAFRGDDM SYPTVGISFG LDVIYTALSQ KETISSTADV FIIPLGTELQ CLQIAQQLRS 360
  361 TTSLKIELEL AGRKLKRALN YANKENIPYV LIIGEEEICT ETVMLRNMKE GSEVKVPLSS 420
  421 LSNYL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	62.69897
Match:	1httA
Description:	Histidyl-tRNA synthetase (HisRS), C-terminal domain; Histidyl-tRNA synthetase (HisRS)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ligase activity, forming aminoacyl-tRNA and related compounds	7.89468709683036	bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds	7.89468709683036	bayes_pls_golite062009
aminoacyl-tRNA ligase activity	7.88410036819636	bayes_pls_golite062009
ligase activity	6.92073480193262	bayes_pls_golite062009
histidine-tRNA ligase activity	5.91343220471745	bayes_pls_golite062009
phenylalanine-tRNA ligase activity	2.99105702052936	bayes_pls_golite062009
serine-tRNA ligase activity	2.46505535069103	bayes_pls_golite062009
glycine-tRNA ligase activity	2.29229136935761	bayes_pls_golite062009
threonine-tRNA ligase activity	2.18642354927	bayes_pls_golite062009
catalytic activity	1.99372273395202	bayes_pls_golite062009
alanine-tRNA ligase activity	1.82594054955281	bayes_pls_golite062009
lysine-tRNA ligase activity	1.72324031407565	bayes_pls_golite062009
asparagine-tRNA ligase activity	0.921492123574877	bayes_pls_golite062009
binding	0.916222310895772	bayes_pls_golite062009
transcription regulator activity	0.375542987753806	bayes_pls_golite062009
nucleic acid binding	0.281662799812287	bayes_pls_golite062009
DNA binding	0.0309732052586011	bayes_pls_golite062009
aspartate-tRNA ligase activity	0.00572514744734753	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: