YRC Public Data Repository - Protein Structure Prediction

Protein:	PUR7_GEOSL
Organism:	Geobacter sulfurreducens PCA
Length:	296 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PUR7_GEOSL.

Description	E-value	Query Range	Subject Range
PUR7_GEOMG - Phosphoribosylaminoimidazole-succinocarboxamide synthase OS=Geobacter metallireducens (strain GS-15 ...	408.0	[0..1]	[296..1]
PUR7_PELPD - Phosphoribosylaminoimidazole-succinocarboxamide synthase OS=Pelobacter propionicus (strain DSM 2379)...	406.0	[0..1]	[293..1]
PUR7_GEODF - Phosphoribosylaminoimidazole-succinocarboxamide synthase OS=Geobacter daltonii (strain DSM 22248 / J...	404.0	[0..1]	[296..1]
gi\|67980343, gi\|... - gi\|95930880\|ref\|ZP_01313611.1\| phosphoribosylaminoimidazole-succinocarboxamide synthase [Desulfuromo...	400.0	[0..1]	[292..1]
PUR7_METFK - Phosphoribosylaminoimidazole-succinocarboxamide synthase OS=Methylobacillus flagellatus (strain KT /...	399.0	[0..1]	[294..1]
gi\|170697610, gi... - gi\|170697610\|ref\|ZP_02888699.1\| phosphoribosylaminoimidazole-succinocarboxamide synthase [Burkholder... gi\|115352723, gi... - gi\|74019294\|ref\|ZP_00689911.1\| SAICAR synthetase [Burkholderia ambifaria AMMD], gi\|72607968\|gb\|EAO43...	395.0	[0..3]	[294..2]
gi\|134139988, gi... - gi\|67548628\|ref\|ZP_00426513.1\| SAICAR synthetase [Burkholderia vietnamiensis G4], gi\|67530067\|gb\|EAM...	395.0	[0..3]	[294..2]
gi\|78067425, gi\|... - gi\|78067425\|ref\|YP_370194.1\| phosphoribosylaminoimidazole-succinocarboxamide synthase [Burkholderia ...	394.0	[0..3]	[294..2]
gi\|124894138, gi... - gi\|84362731\|ref\|ZP_00987345.1\| COG0152: Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synt...	394.0	[0..3]	[294..2]
gi\|198037217, gi... - gi\|206561175\|ref\|YP_002231940.1\| phosphoribosylaminoimidazole-succinocarboxamide synthase [Burkholde... gi\|118707488, gi... - gi\|170733989\|ref\|YP_001765936.1\| phosphoribosylaminoimidazole-succinocarboxamide synthase [Burkholde... gi\|194558320, gi... - gi\|84355616\|ref\|ZP_00980493.1\| COG0152: Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synt... gi\|116648734, gi... - gi\|67663919\|ref\|ZP_00461197.1\| SAICAR synthetase [Burkholderia cenocepacia HI2424], gi\|67102435\|gb\|E... gi\|67093431, gi\|... - gi\|67659007\|ref\|ZP_00456374.1\| SAICAR synthetase [Burkholderia cenocepacia AU 1054], gi\|67093431\|gb\|...	393.0	[0..3]	[295..2]

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Predicted Domain #1

Region A:
Residues: [1-296]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAELVLKTDF PDLKLAGRGK VRDIYDLGDA LLIVTTDRIS AFDVIMNEAI PDKGYVLTQI  60
   61 SSFWFRQMED IIPNHIISTD VKDFPAECQK YAAQLEGRSM LVKKAKPLPV ECIVRGYISG 120
  121 SGWKDYKATG AICGITLPAG LVESDKLEEP IFTPSTKAEL GEHDENISFD KCVELIGREL 180
  181 AEKIRDVTIA IYKRARDIAD TKGIIIADTK FEYGIYNGEL IIIDECMTPD SSRFWPKDSY 240
  241 KPGGAQPSFD KQFLRDYLET LDWGKTAPAP PLPEEIVRKT GEKYMEALVR LTGKGK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	93.69897
Match:	1a48A
Description:	SAICAR SYNTHASE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
phosphoribosylaminoimidazolesuccinocarboxamide synthase activity	3.13563725397088	bayes_pls_golite062009
ligase activity	2.72434998554003	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	2.66954072457689	bayes_pls_golite062009
kinase activity	2.47933488612871	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	2.15276561572143	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	2.151446378007	bayes_pls_golite062009
catalytic activity	1.87792712964225	bayes_pls_golite062009
acid-amino acid ligase activity	1.8159520385203	bayes_pls_golite062009
binding	1.66593042987179	bayes_pls_golite062009
transferase activity	1.5866347320867	bayes_pls_golite062009
inositol or phosphatidylinositol kinase activity	1.35725237917644	bayes_pls_golite062009
lipid kinase activity	0.486217075920953	bayes_pls_golite062009
protein binding	0.382966234080422	bayes_pls_golite062009
protein kinase activity	0.135906673863896	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: