YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|24346555, gi\|...
Organism:	Shewanella oneidensis MR-1
Length:	527 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24346555, gi|....

Description	E-value	Query Range	Subject Range
gi\|67849756, gi\|... - gi\|67916294\|ref\|ZP_00510010.1\| FAD-dependent pyridine nucleotide-disulphide oxidoreductase [Clostrid...	397.0	[0..2]	[511..3]
gi\|216304 - gi\|216304\|dbj\|BAA01545.1\| NADH dehydrogenase, alpha-2 subunit [Bacillus alcalophilus] gi\|80165 - gi\|80165\|pir\|\|JX0166 NADH oxidase (hydrogen peroxide-forming) (EC 1.6.-.-) - Bacillus sp. (strain YN... DHNA_BACYN - NADH dehydrogenase OS=Bacillus sp. (strain YN-1) GN=ahpF PE=1 SV=1	385.0	[0..1]	[511..2]
gi\|77459149, gi\|... - gi\|77459149\|ref\|YP_348655.1\| pyridine nucleotide-disulphide oxidoreductase class-II [Pseudomonas flu...	383.0	[0..1]	[511..1]
gi\|116053860, gi... - gi\|116053860\|ref\|YP_788297.1\| alkyl hydroperoxide reductase subunit F [Pseudomonas aeruginosa UCBPP-...	378.0	[0..1]	[511..1]
AHPF_PSEAE - Alkyl hydroperoxide reductase subunit F OS=Pseudomonas aeruginosa GN=ahpF PE=3 SV=1 AHPF_PSEAE - Alkyl hydroperoxide reductase subunit F OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / P...	377.0	[0..1]	[511..1]
gi\|91778892, gi\|... - gi\|91778892\|ref\|YP_554100.1\| AhpF [Burkholderia xenovorans LB400], gi\|91691552\|gb\|ABE34750.1\| alkyl ...	377.0	[0..1]	[511..1]
gi\|46313101, gi\|... - gi\|78062803\|ref\|YP_372711.1\| FAD-dependent pyridine nucleotide-disulphide oxidoreductase [Burkholder...	377.0	[0..1]	[512..1]
gi\|67102760, gi\|... - gi\|67663733\|ref\|ZP_00461013.1\| FAD-dependent pyridine nucleotide-disulphide oxidoreductase [Burkhold... gi\|105895998, gi... - gi\|67660266\|ref\|ZP_00457616.1\| FAD-dependent pyridine nucleotide-disulphide oxidoreductase [Burkhold...	376.0	[0..1]	[512..1]
gi\|216220, gi\|625205 - pir\|\|A49911 NADH oxidase (hydrogen peroxide-forming) (EC 1.6.-.-) - Amphibacillus xylanus, gi\|21622... gi\|216220\|dbj\|BA... - NADH oxidase [Amphibacillus xylanus]	376.0	[0..1]	[495..1]
gi\|48764781 - ref\|ZP_00269332.1\| COG3634: Alkyl hydroperoxide reductase, large subunit [Rhodospirillum rubrum] gi\|83575667, gi\|... - gi\|83592753\|ref\|YP_426505.1\| thioredoxin-disulfide reductase [Rhodospirillum rubrum ATCC 11170], gi\|...	375.0	[0..1]	[513..1]

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Predicted Domain #1

Region A:
Residues: [1-527]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLDANLKNQL QTYLQNLKRP VELVVSADES KKSQELKSLV NDIVSLSTFV SLKEAQGQRT  60
   61 PAMTVVNPAL NTQISFAGLP MGHEFTSLVL ALLHSGGHPI KLSDDIIEQI RNLPGKYEFE 120
  121 TYVSLTCQNC PDVVQALNMM AAINPNITNV MIDGALFQDE VASRNIMAVP SVYLNGEVFA 180
  181 AGRISIGEIL NKLDTGAASR KAEELSQKAP YEVLVVGGGP AGAAAAIYAA RKGLRTGIVA 240
  241 DKFGGQVAET VGIENFISVK ATEGPKLVAN LEAHVRDYEV DIMDNQKAVK LASDGLFELE 300
  301 LASGAKLRSR TVLLATGARW REMNVPGEKE YRGKGVAYCP HCDGPLFKGK RVAVIGGGNS 360
  361 GIEAAIDLAN IVEHVTVLEF DSKLRADDVL QRKAASMGNI KIITQAMTTE VTGDGTRVNG 420
  421 LNYTDRATGE SHHIALAGIF VQIGLVPNAE WLKGTVDLTP RGEIIVDERG QTSVPGVFAA 480
  481 GDVTNSPYKQ IIIAMGSGAN ASLGAFDYLI RHSDDSTETK TTDTKAA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	95.221849
Match:	1hyuA
Description:	Alkyl hydroperoxide reductase subunit F (AhpF), C-terminal domains; Alkyl hydroperoxide reductase subunit F (AhpF), N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
alkyl hydroperoxide reductase activity	4.29610283853788	bayes_pls_golite062009
antioxidant activity	3.8464796631544	bayes_pls_golite062009
oxidoreductase activity, acting on peroxide as acceptor	3.43831566988273	bayes_pls_golite062009
peroxidase activity	3.43831566988273	bayes_pls_golite062009
glutathione peroxidase activity	2.56524997297011	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors	2.23310780102446	bayes_pls_golite062009
peroxiredoxin activity	2.12777217096121	bayes_pls_golite062009
thioredoxin peroxidase activity	1.96134566495756	bayes_pls_golite062009
transcription regulator activity	1.90357236955554	bayes_pls_golite062009
selenium binding	1.67987004910726	bayes_pls_golite062009
protein disulfide oxidoreductase activity	1.47769936616412	bayes_pls_golite062009
disulfide oxidoreductase activity	1.32811008894503	bayes_pls_golite062009
binding	1.25802922431343	bayes_pls_golite062009
transporter activity	0.775169788737542	bayes_pls_golite062009
dihydrolipoyl dehydrogenase activity	0.69501605197281	bayes_pls_golite062009
catalytic activity	0.672192331361968	bayes_pls_golite062009
hydrolase activity	0.517269321619613	bayes_pls_golite062009
transmembrane transporter activity	0.516718923379533	bayes_pls_golite062009
substrate-specific transporter activity	0.198172638251773	bayes_pls_golite062009
oxygen-dependent protoporphyrinogen oxidase activity	0.1498172520052	bayes_pls_golite062009
protein binding	0.134341907247724	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: