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View Structure Prediction Details

Protein: ASSY_ARATH
Organism: Arabidopsis thaliana
Length: 494 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ASSY_ARATH.

Description E-value Query
Range
Subject
Range
gi|7269334, gi|7... - gi|7438038|pir||T06667 argininosuccinate synthase (EC 6.3.4.5) - Arabidopsis thaliana, gi|7269334|em...
477.0 [0..1] [494..1]

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Predicted Domain #1
Region A:
Residues: [1-96]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEISATSFP SSSSSALVIR SSHNGSLKCQ NVAVPKTTSQ FQELSLKRSQ LVGNAVVTGH  60
   61 VTGSRSCKNQ AIRAVLSGDG TALTTDSKEA GLRGKL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 59.30103
Match: 1gpmA
Description: GMP synthetase; GMP synthetase, central domain; GMP synthetase C-terminal dimerisation domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [97-494]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KKVVLAYSGG LDTSVIVPWL KENYGCEVVC FTADVGQGIK ELEGLEQKAK ASGASQLVVK  60
   61 DLTEEFVKDF IFPCLRAGAI YERKYLLGTS MARPVIAKAM VDVAAEVGAD AVAHGCTGKG 120
  121 NDQVRFELTF FSLNPELKVV APWREWEIQG REDAIEYAKK HNVPVPVTKK SIYSRDRNLW 180
  181 HLSHEGDLLE DPANEPKKDM YMMSVDPEDA PDQPEYIEIG IESGLPVALN GKALSPATLL 240
  241 AELNTIGGKH GIGRIDMVEN RLVGMKSRGV YETPGGTILF AAVQELESLT LDRESIQVKD 300
  301 TLALKYAEMV YAGRWFDPLR ESMDAFMEKI TETTTGSVTL KLYKGSVSVT GRQSPNSLYR 360
  361 QDISSFEGSE IYNQADAAGF IRLYGLPMKI RAMLKKIS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 127.0
Match: 1j1zA
Description: Argininosuccinate synthetase, N-terminal domain; Argininosuccinate synthetase, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
argininosuccinate synthase activity 5.55984418125277 bayes_pls_golite062009
ligase activity 2.54636182867584 bayes_pls_golite062009
catalytic activity 1.4716728594386 bayes_pls_golite062009
binding 0.949267645607863 bayes_pls_golite062009
protein binding 0.476576076629648 bayes_pls_golite062009
asparagine synthase (glutamine-hydrolyzing) activity 0.3673193848392 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 0.204705463374024 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle