YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Catalysis of the transfer of the amide nitrogen of glutamine to a variety of substrates. GATases catalyze two separate reactions at two active sites, which are located either on a single polypeptide chain or on different subunits. In the glutaminase reaction, glutamine is hydrolyzed to glutamate and ammonia, which is added to an acceptor substrate in the synthase reaction. Catalysis of the reaction: ATP + L-aspartate + L-glutamine = AMP + diphosphate + L-asparagine + L-glutamate. Catalysis of the ligation of two substances via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: asparagine synthase (glutamine-hydrolyzing) activity
Acc: GO:0004066
Aspect: Molecular Function
Desc: Catalysis of the reaction: ATP + L-aspartate + L-glutamine = AMP + diphosphate + L-asparagine + L-glutamate.
Synonyms:
  • AS-B activity
  • AS
  • asparagine synthetase (glutamine-hydrolyzing) activity
  • asparagine synthase (glutamine-hydrolysing)
  • asparagine synthetase (glutamine-hydrolysing)
  • asparagine synthetase B activity
  • glutamine-dependent asparagine synthetase activity
  • L-aspartate:L-glutamine amido-ligase (AMP-forming)
Proteins in PDR annotated with:
   This term: 34 [Search]
   Term or descendants: 34 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004066 - asparagine synthase (glutamine-hydrolyzing) activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle