YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|229695413, gi...
Organism:	Yersinia pestis biovar Orientalis str. PEXU2
Length:	178 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|229695413, gi....

Description	E-value	Query Range	Subject Range
TILS_LISIN - Bifunctional protein TilS/HprT OS=Listeria innocua serovar 6a (strain CLIP 11262) GN=tilS/hprT PE=3 ... TILS_LISIN - Bifunctional protein tilS/hprT OS=Listeria innocua GN=tilS/hprT PE=3 SV=1	3.0E-40	[2..176]	[472..644]
gi\|224500330 - gi\|224500330\|ref\|ZP_03668679.1\| hypothetical protein LmonF1_11939 [Listeria monocytogenes Finland 19... gi\|224503461 - gi\|224503461\|ref\|ZP_03671768.1\| hypothetical protein LmonFR_13287 [Listeria monocytogenes FSL R2-561... gi\|126941298, gi... - gi\|254900996\|ref\|ZP_05260920.1\| hypothetical protein LmonJ_14318 [Listeria monocytogenes J0161], gi\|... gi\|254913936, gi... - gi\|254913936\|ref\|ZP_05263948.1\| hypothetical protein LmonJ2_14108 [Listeria monocytogenes J2818], gi... gi\|133733948, gi... - gi\|254938274\|ref\|ZP_05269971.1\| hypothetical protein LmonF6_14141 [Listeria monocytogenes F6900], gi... gi\|47014358, gi\|... - gi\|47097258\|ref\|ZP_00234818.1\| conserved hypothetical protein/hypoxanthine phosphoribosyltransferase... TILS_LISMO - Bifunctional protein TilS/HprT OS=Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) ... TILS_LISMO - Bifunctional protein tilS/hprT OS=Listeria monocytogenes GN=tilS/hprT PE=3 SV=1	6.0E-40	[2..176]	[472..644]
TILS_LISMF - Bifunctional protein TilS/HprT OS=Listeria monocytogenes serotype 4b (strain F2365) GN=tilS/hprT PE=...	7.0E-40	[2..176]	[472..644]
gi\|226222848, gi... - gi\|226222848\|ref\|YP_002756955.1\| hypothetical protein Lm4b_00217 [Listeria monocytogenes Clip81459],... gi\|47018468, gi\|... - gi\|47093161\|ref\|ZP_00230936.1\| conserved hypothetical protein/hypoxanthine phosphoribosyltransferase... gi\|21667249 - gi\|21667249\|gb\|AAM74001.1\|AF467001_2 YacA/HprT-like protein [Listeria monocytogenes] gi\|153200654, gi... - gi\|254933059\|ref\|ZP_05266418.1\| hypothetical protein LmonH_11532 [Listeria monocytogenes HPB2262], g...	1.0E-39	[2..176]	[472..644]
gi\|51595073, gi\|... - gi\|51595073\|ref\|YP_069264.1\| hypoxanthine-guanine phosphoribosyltransferase [Yersinia pseudotubercul... Q66EH0\|Q66EH0_YERPS - Hypoxanthine phosphoribosyltransferase - Yersinia pseudotuberculosis	3.0E-39	[1..178]	[1..178]
gi\|77957545 - gi\|77957545\|ref\|ZP_00821598.1\| COG0634: Hypoxanthine-guanine phosphoribosyltransferase [Yersinia ber...	1.0E-38	[1..178]	[1..178]
gi\|49612776, gi\|... - gi\|50122250\|ref\|YP_051417.1\| hypoxanthine-guanine phosphoribosyltransferase [Erwinia carotovora subs...	2.0E-38	[1..177]	[2..178]
gi\|165915285, gi... - gi\|89104450\|ref\|ZP_01176993.1\| COG0634: Hypoxanthine-guanine phosphoribosyltransferase [Yersinia pes... gi\|167051668, gi... - gi\|167399164\|ref\|ZP_02304688.1\| hypoxanthine phosphoribosyltransferase [Yersinia pestis biovar Antiq... gi\|165990951, gi... - gi\|166010044\|ref\|ZP_02230942.1\| hypoxanthine phosphoribosyltransferase [Yersinia pestis biovar Antiq... gi\|165922374, gi... - gi\|165925762\|ref\|ZP_02221594.1\| hypoxanthine phosphoribosyltransferase [Yersinia pestis biovar Orien... gi\|167420579, gi... - gi\|167420579\|ref\|ZP_02312332.1\| hypoxanthine phosphoribosyltransferase [Yersinia pestis biovar Orien... gi\|108780814, gi... - gi\|108808901\|ref\|YP_652817.1\| hypoxanthine phosphoribosyltransferase [Yersinia pestis Antiqua], gi\|1...	2.0E-38	[2..178]	[5..181]
gi\|45434992, gi\|... - gi\|45440137\|ref\|NP_991676.1\| hypoxanthine-guanine phosphoribosyltransferase [Yersinia pestis biovar ... gi\|166214091, gi... - gi\|166214091\|ref\|ZP_02240126.1\| hypoxanthine phosphoribosyltransferase [Yersinia pestis biovar Antiq... gi\|145600206, gi... - gi\|145600206\|ref\|YP_001164282.1\| hypoxanthine phosphoribosyltransferase [Yersinia pestis Pestoides F... gi\|167423632, gi... - gi\|167423632\|ref\|ZP_02315385.1\| hypoxanthine phosphoribosyltransferase [Yersinia pestis biovar Media... gi\|108810845, gi... - gi\|108810845\|ref\|YP_646612.1\| hypoxanthine phosphoribosyltransferase [Yersinia pestis Nepal516], gi\|... gi\|22124691, gi\|... - gi\|22124691\|ref\|NP_668114.1\| hypoxanthine-guanine phosphoribosyltransferase [Yersinia pestis KIM], g... gi\|162351808, gi... - gi\|77634827\|ref\|ZP_00796920.1\| COG0634: Hypoxanthine-guanine phosphoribosyltransferase [Yersinia pes...	2.0E-38	[2..178]	[5..181]
gi\|123441069, gi... - gi\|123441069\|ref\|YP_001005058.1\| hypoxanthine phosphoribosyltransferase [Yersinia enterocolitica sub... gi\|77977265 - gi\|77977265\|ref\|ZP_00832718.1\| COG0634: Hypoxanthine-guanine phosphoribosyltransferase [Yersinia int...	2.0E-38	[1..178]	[1..178]

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Predicted Domain #1

Region A:
Residues: [1-178]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRHTVEVMIS EQEVKTRIAE LGRQISEHYR DSGSDMVLVG LLRGSFMFMA DLCRAIDVSH  60
   61 EVDFMTASSY GNGMSTTRDV KILKDLDEDI RGKDVLIVED IIDSGNTLSK VREILQLRGP 120
  121 KSLAICTLLD KPERREVHVP VEWVGFTIPD EFVVGYGIDY AQRYRHLPYV GKVVTLDE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	38.522879
Match:	1j7jA
Description:	Hypoxanthine PRTase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
adenine phosphoribosyltransferase activity	4.07252508868782	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	3.91023158228049	bayes_pls_golite062009
hypoxanthine phosphoribosyltransferase activity	3.89356447922614	bayes_pls_golite062009
transferase activity	2.73727660668741	bayes_pls_golite062009
nucleobase binding	2.70671399975507	bayes_pls_golite062009
purine binding	2.63033967717893	bayes_pls_golite062009
transferase activity, transferring pentosyl groups	2.53679639481311	bayes_pls_golite062009
uracil phosphoribosyltransferase activity	2.36237864658341	bayes_pls_golite062009
catalytic activity	2.30431811394775	bayes_pls_golite062009
amidophosphoribosyltransferase activity	1.6596316647688	bayes_pls_golite062009
ribose phosphate diphosphokinase activity	1.51875493459374	bayes_pls_golite062009
protein binding	1.02514711359042	bayes_pls_golite062009
adenine binding	0.817887117933035	bayes_pls_golite062009
diphosphotransferase activity	0.749909396904601	bayes_pls_golite062009
binding	0.644392905117932	bayes_pls_golite062009
nucleic acid binding	0.439453264070391	bayes_pls_golite062009
transcription regulator activity	0.369893745269311	bayes_pls_golite062009
DNA binding	0.275043319532312	bayes_pls_golite062009
orotate phosphoribosyltransferase activity	0.148898393751978	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: