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View Structure Prediction Details

Protein: gi|30686918
Organism: Arabidopsis thaliana
Length: 1072 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30686918.

Description E-value Query
Range
Subject
Range
CHR17_ARATH - ISWI chromatin-remodeling complex ATPase CHR17 OS=Arabidopsis thaliana GN=CHR17 PE=1 SV=1
748.0 [0..1] [1069..1]

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Predicted Domain #1
Region A:
Residues: [1-160]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MARASKREVS SDEAYSSEEE EQVNDQANVE EDDDELEAVA RSAGSDEEDV APDEAPVSDD  60
   61 EVVPVEDDAE EDEEDEEKAE ISKREKARLK EMQKMKKQKI QQILDSQNAS IDADMNNKGK 120
  121 GRIKYLLQQT ELFAHFAKSD PSPSQKKGKG RGRHSSKLTE 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [161-744]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EEEDEECLKE EEGGIVGSGG TRLLTQPACI QGKLRDYQLA GLNWLIRLYE NGINGILADE  60
   61 MGLGKTLQTI SLLAYLHEYR GINGPHMVVA PKSTLGNWMN EIRRFCPVLR AVKFLGNPEE 120
  121 RRHIREELLV AGKFDICVTS FEMAIKEKTT LRRFSWRYII IDEAHRIKNE NSLLSKTMRL 180
  181 FSTNYRLLIT GTPLQNNLHE LWALLNFLLP EVFSSAETFD EWFQISGEND QQEVVQQLHK 240
  241 VLRPFLLRRL KSDVEKGLPP KKETILKVGM SQMQKQYYKA LLQKDLEVVN GGGERKRLLN 300
  301 IAMQLRKCCN HPYLFQGAEP GPPYTTGDHL VTNAGKMVLL DKLLPKLKDR DSRVLIFSQM 360
  361 TRLLDILEDY LMYRGYQYCR IDGNTGGDER DASIEAYNKP GSEKFVFLLS TRAGGLGINL 420
  421 ATADVVILYD SDWNPQVDLQ AQDRAHRIGQ KKEVQVFRFC TENAIEAKVI ERAYKKLALD 480
  481 ALVIQQGRLA EQKTVNKDEL LQMVRYGAEM VFSSKDSTIT DEDIDRIIAK GEEATAELDA 540
  541 KMKKFTEDAI QFKMDDSADF YDFDDDNKDE SKVDFKKIVS ENWN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 76.09691
Match: 1z3iX
Description: Structure of the SWI2/SNF2 chromatin remodeling domain of eukaryotic Rad54
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
general RNA polymerase II transcription factor activity 3.1726526166851 bayes_pls_golite062009
binding 2.64537357529343 bayes_pls_golite062009
nucleic acid binding 2.51683451033161 bayes_pls_golite062009
DNA binding 2.12258000781149 bayes_pls_golite062009
transcription regulator activity 2.09345198747025 bayes_pls_golite062009
DNA-dependent ATPase activity 1.23094623498843 bayes_pls_golite062009
protein binding 1.22129154759482 bayes_pls_golite062009
purine ribonucleotide binding 1.21658213854831 bayes_pls_golite062009
ribonucleotide binding 1.21652144153182 bayes_pls_golite062009
purine nucleotide binding 1.21571071905795 bayes_pls_golite062009
nucleotide binding 1.20347573865566 bayes_pls_golite062009
motor activity 1.14667913749579 bayes_pls_golite062009
histone acetyltransferase activity 1.05990253628867 bayes_pls_golite062009
lysine N-acetyltransferase activity 1.05990253628867 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
transcription activator activity 0.889929694023098 bayes_pls_golite062009
transcription factor activity 0.887108427603557 bayes_pls_golite062009
protein-DNA loading ATPase activity 0.729056749897011 bayes_pls_golite062009
steroid hormone receptor binding 0.647625526012423 bayes_pls_golite062009
structure-specific DNA binding 0.620212706423176 bayes_pls_golite062009
helicase activity 0.6191010101321 bayes_pls_golite062009
microtubule motor activity 0.60036517876321 bayes_pls_golite062009
DNA helicase activity 0.57378485697982 bayes_pls_golite062009
sequence-specific DNA binding 0.543891899378373 bayes_pls_golite062009
cytoskeletal protein binding 0.500462538667228 bayes_pls_golite062009
DNA clamp loader activity 0.49811753387851 bayes_pls_golite062009
double-stranded DNA binding 0.49000746592281 bayes_pls_golite062009
guanyl nucleotide binding 0.388587892299301 bayes_pls_golite062009
guanyl ribonucleotide binding 0.372638007722845 bayes_pls_golite062009
GTP binding 0.364508542344128 bayes_pls_golite062009
hormone receptor binding 0.351501100511918 bayes_pls_golite062009
centromeric DNA binding 0.322818640526369 bayes_pls_golite062009
purine NTP-dependent helicase activity 0.29664013896754 bayes_pls_golite062009
ATP-dependent helicase activity 0.29664013896754 bayes_pls_golite062009
ATP-dependent DNA helicase activity 0.24825301806267 bayes_pls_golite062009
nuclear hormone receptor binding 0.246160342138071 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.243902356228423 bayes_pls_golite062009
GTPase activity 0.234351968078991 bayes_pls_golite062009
RNA helicase activity 0.18426050934025 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.147579541298736 bayes_pls_golite062009
RNA-dependent ATPase activity 0.14606996093053 bayes_pls_golite062009
pyrophosphatase activity 0.133017653323467 bayes_pls_golite062009
ATP-dependent RNA helicase activity 0.13050483816765 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.113504049290503 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.111293884322157 bayes_pls_golite062009
structural constituent of ribosome 0.089234257580272 bayes_pls_golite062009
actin binding 0.00482938540552702 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [745-1072]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPPKRERKRN YSEVEYFKQT LRQGAPAKPK EPRIPRMPQL HDFQFFNIQR LTELYEKEVR  60
   61 YLMQAHQKTQ MKDTIEVDEP EEVGDPLTAE EVEEKELLLE EGFSTWSRRD FNAFIRACEK 120
  121 YGRNDIKSIA SEMEGKTEEE VERYAQVFQV RYKELNDYDR IIKNIERGEA RISRKDEIMK 180
  181 AIGKKLDRYR NPWLELKIQY GQNKGKLYNE ECDRFMICMV HKLGYGNWDE LKAAFRTSPL 240
  241 FRFDWFVKSR TTQELARRCD TLIRLIEKEN QEFDERERQA RKEKKLSKSA TPSKRPSGRQ 300
  301 ANESPSSLLK KRKQLSMDDY VSSGKRRK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 54.69897
Match: 1ofcX
Description: nucleosome recognition module of ISWI ATPase
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle