YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|3318870, gi\|3...
Organism:	Escherichia coli
Length:	271 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|3318870, gi|3....

Description	E-value	Query Range	Subject Range
gi\|223490097, gi... - gi\|254478108\|ref\|ZP_05091491.1\| Periplasmic binding proteins and sugar binding domain of the LacI fa... gi\|20515188, gi\|... - gi\|20806732\|ref\|NP_621903.1\| periplasmic sugar-binding proteins [Thermoanaerobacter tengcongensis MB... gi\|20806732 - gi\|20806732\|ref\|NP_621903.1\| Periplasmic sugar-binding proteins [Thermoanaerobacter tengcongensis MB...	262.0	[0..2]	[271..40]
gi\|167038831, gi... - gi\|167038831\|ref\|YP_001661816.1\| periplasmic binding protein/LacI transcriptional regulator [Thermoa... gi\|242258204, gi... - gi\|242258204\|ref\|ZP_04803030.1\| transcriptional regulator, LacI family [Thermoanaerobacter sp. X513]...	259.0	[0..2]	[271..62]
gi\|76587214, gi\|... - gi\|76797424\|ref\|ZP_00779743.1\| Periplasmic binding protein/LacI transcriptional regulator [Thermoana... gi\|241882995, gi... - gi\|241904642\|ref\|ZP_04789321.1\| Monosaccharide-transporting ATPase [Thermoanaerobacter brockii subsp... gi\|242258199, gi... - gi\|242258199\|ref\|ZP_04803025.1\| Monosaccharide-transporting ATPase [Thermoanaerobacter sp. X513], gi... gi\|114843563, gi... - gi\|167038836\|ref\|YP_001661821.1\| monosaccharide-transporting ATPase [Thermoanaerobacter sp. X514], g...	258.0	[0..2]	[270..38]
gi\|51891908, gi\|... - gi\|51891908\|ref\|YP_074599.1\| LacI family transcriptional repressor [Symbiobacterium thermophilum IAM...	253.0	[0..3]	[270..60]
gi\|37200774, gi\|... - gi\|37676233\|ref\|NP_936629.1\| transcriptional regulator [Vibrio vulnificus YJ016], gi\|37200774\|dbj\|BA...	248.0	[0..2]	[270..61]
gi\|83745729, gi\|... - gi\|83745729\|ref\|ZP_00942786.1\| Transcriptional regulator, LacI family [Ralstonia solanacearum UW551]... gi\|207743639, gi... - gi\|207743639\|ref\|YP_002260031.1\| transcriptional regulatory dna-binding repressor protein [Ralstonia...	248.0	[0..3]	[271..61]
gi\|238787882, gi... - gi\|77973820\|ref\|ZP_00829365.1\| COG1879: ABC-type sugar transport system, periplasmic component [Yers...	247.0	[0..1]	[271..26]
gi\|56421761, gi\|... - gi\|56421761\|ref\|YP_149079.1\| ribose ABC transporter (ribose-binding protein) [Geobacillus kaustophil...	247.0	[0..3]	[268..42]

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Predicted Domain #1

Region A:
Residues: [1-271]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KDTIALVVST LNNPFFVSLK DGAQKEADKL GYNLVVLDSQ NNPAKELANV QDLTVRGTKI  60
   61 LLINPTDSDA VGNAVKMANQ ANIPVITLDR QATKGEVVSH IASDNVLGGK IAGDYIAKKA 120
  121 GEGAKVIELQ GIAGTSAARE RGEGFQQAVA AHKFNVLASQ PADFDRIKGL NVMQNLLTAH 180
  181 PDVQAVFAQN DEMALGALRA LQTAGKSDVM VVGFDGTPDG EKAVNDGKLA ATIAQLPDQI 240
  241 GAKGVETADK VLKGEKVQAK YPVDLKLVVK Q

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	65.30103
Match:	1dbpA
Description:	IDENTICAL MUTATIONS AT CORRESPONDING POSITIONS IN TWO HOMOLOGOUS PROTEINS WITH NON-IDENTICAL EFFECTS
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
pentose transmembrane transporter activity	2.47679209577816	bayes_pls_golite062009
D-ribose transmembrane transporter activity	2.47679209577816	bayes_pls_golite062009
D-ribose-importing ATPase activity	2.47679209577816	bayes_pls_golite062009
monosaccharide-transporting ATPase activity	2.39566008731161	bayes_pls_golite062009
carbohydrate transmembrane transporter activity	1.15685021131727	bayes_pls_golite062009
binding	1.13059008752468	bayes_pls_golite062009
monosaccharide transmembrane transporter activity	0.53966958074777	bayes_pls_golite062009
transporter activity	0.399752289774857	bayes_pls_golite062009
transmembrane transporter activity	0.265529619623159	bayes_pls_golite062009
sugar transmembrane transporter activity	0.23981626136031	bayes_pls_golite062009
active transmembrane transporter activity	0.0415259877073471	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: