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Bait Protein: CWC25
Organism: Saccharomyces cerevisiae
Publication: Hazbun TR, et al. (2003) Assigning function to yeast proteins by integration of technologies. Mol Cell 12(6):1353-65
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  Hit Protein Protein Desc Sequence Count Spectrum Count Sequence Coverage NSAF Mol. Wt.
[View Peptides]   CWC25 Heat-stable protein required for the first step of pre-mRNA splicing; component of a complex contain... 9 25 45.8% 0.202 20374
[View Peptides]   SNT309 Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms... 4 16 42.9% 0.132 20709
[View Peptides]   PRP19 Splicing factor associated with the spliceosome; contains a U-box, a motif found in a class of ubiqu... 14 30 41.9% 0.0862 56570
[View Peptides]   SMD1 Core Sm protein Sm D1; part of heteroheptameric complex (with Smb1p, Smd2p, Smd3p, Sme1p, Smx3p, and... 3 9 34.2% 0.0891 16275
[View Peptides]   CLF1 Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms... 9 14 22.4% 0.0294 82445
[View Peptides]   LEA1 Component of U2 snRNP; disruption causes reduced U2 snRNP levels; physically interacts with Msl1p; p... 3 3 21.0% 0.0182 27193
[View Peptides]   YJU2 Essential protein required for pre-mRNA splicing; associates transiently with the spliceosomal NTC (... 3 3 16.5% 0.0156 32312
[View Peptides]   SYF2 Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms... 2 2 15.8% 0.0134 24803
[View Peptides]   ISY1 Member of NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms of ... 2 6 15.3% 0.0369 28024
[View Peptides]   ECM2 Pre-mRNA splicing factor, facilitates the cooperative formation of U2/U6 helix II in association wit... 3 4 15.1% 0.0159 40925
[View Peptides]   SNU114 GTPase component of U5 snRNP involved in mRNA splicing via spliceosome; binds directly to U5 snRNA; ... 8 12 12.3% 0.0172 114041
[View Peptides]   CWC22 Essential protein, component of a complex containing Cef1p, has similarity to S. pombe Cwf22p; putat... 5 7 12.3% 0.0175 67294
[View Peptides]   SYF1 Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms... 5 14 11.1% 0.0235 100229
[View Peptides]   CWC2 Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms... 2 4 10.9% 0.017 38431
[View Peptides]   PRP46 Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms... 3 5 9.8% 0.016 50700
[View Peptides]   CEF1 Essential splicing factor; associated with Prp19p and the spliceosome, contains an N-terminal c-Myb ... 3 6 9.0% 0.0147 67731
[View Peptides]   PRP8 Component of the U4/U6-U5 snRNP complex, involved in the second catalytic step of splicing; mutation... 12 18 7.7% 0.0108 279502
[View Peptides]   LAT1 Dihydrolipoamide acetyltransferase component (E2) of pyruvate dehydrogenase complex, which catalyzes... 2 3 7.5% 0.00899 51818
[View Peptides]   SNX4 Sorting nexin, involved in retrieval of late-Golgi SNAREs from post-Golgi endosomes to the trans-Gol... 2 2 7.3% 0.00683 49002
[View Peptides]   CDC40 Pre-mRNA splicing factor, important for catalytic step II of pre-mRNA splicing and plays a role in c... 2 3 5.7% 0.00953 52048
[View Peptides]   SLM1 Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p; acts downstream of Mss4p in ... 2 2 5.2% 0.00421 77995
[View Peptides]   STO1 Large subunit of the nuclear mRNA cap-binding protein complex, interacts with Npl3p to carry nuclear... 2 3 3.9% 0.00503 100017
[View Peptides]   SPT5 Protein involved in regulating Pol I and Pol II transcription and pre-mRNA processing; forms a compl... 2 2 3.6% 0.00272 115650
[View Peptides]   TRS130 One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates... 2 4 2.8% 0.00524 128131
[View Peptides]   SMC1 Subunit of the multiprotein cohesin complex, essential protein involved in chromosome segregation an... 2 2 2.5% 0.00236 141280
[View Peptides]   DOP1 Golgi-localized, leucine-zipper domain containing protein; involved in endosome to Golgi transport, ... 2 2 1.8% 0.0017 194686

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