Bait Protein: | PSF2 |
Organism: | Saccharomyces cerevisiae |
Publication: | Hazbun TR, et al. (2003) Assigning function to yeast proteins by integration of technologies. Mol Cell 12(6):1353-65 |
Comments: | No comments. |
Raw Data: |
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UNFILTERED Run Results:
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Hit Protein | Protein Desc | Sequence Count | Spectrum Count | Sequence Coverage | NSAF | Mol. Wt. | |
[ |
ENO1 | Enolase I, a phosphopyruvate hydratase that catalyzes the conversion of 2-phosphoglycerate to phosph... | 12 | 104 | 28.8% | 0.193 | 46816 |
[ |
PSF1 | Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p), which is localized to DNA replication orig... | 10 | 42 | 56.7% | 0.164 | 24204 |
[ |
SLD5 | Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p), which is localized to DNA replication orig... | 10 | 26 | 36.7% | 0.0716 | 33948 |
[ |
HSC82 | Cytoplasmic chaperone of the Hsp90 family, redundant in function and nearly identical with Hsp82p, a... | 10 | 23 | 20.9% | 0.0264 | 80900 |
[ |
HSP82 | Hsp90 chaperone required for pheromone signaling and negative regulation of Hsf1p; docks with Tom70p... | 10 | 23 | 20.2% | 0.0263 | 81406 |
[ |
EFT2, EFT1 | Elongation factor 2 (EF-2), also encoded by EFT1; catalyzes ribosomal translocation during protein s... | 10 | 18 | 17.9% | 0.0173 | 93289 |
[ |
EFT2, EFT1 | Elongation factor 2 (EF-2), also encoded by EFT1; catalyzes ribosomal translocation during protein s... | 10 | 18 | 17.9% | 0.0173 | 93289 |
[ |
ADH1 | Alcohol dehydrogenase, fermentative isozyme active as homo- or heterotetramers; required for the red... | 7 | 9 | 28.4% | 0.0209 | 36849 |
[ |
FBA1 | Fructose 1,6-bisphosphate aldolase, required for glycolysis and gluconeogenesis; catalyzes conversio... | 6 | 24 | 24.5% | 0.0541 | 39621 |
[ |
PSF2 | Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p), which is localized to DNA replication orig... | 5 | 11 | 26.8% | 0.0418 | 25061 |
[ |
GPM1 | Tetrameric phosphoglycerate mutase, mediates the conversion of 3-phosphoglycerate to 2-phosphoglycer... | 5 | 32 | 21.9% | 0.105 | 27609 |
[ |
TPI1 | Triose phosphate isomerase, abundant glycolytic enzyme; mRNA half-life is regulated by iron availabi... | 4 | 4 | 26.2% | 0.0131 | 26795 |
[ |
TIF1, TIF2 | Translation initiation factor eIF4A, identical to Tif2p; DEA(D/H)-box RNA helicase that couples ATPa... | 4 | 4 | 14.7% | 0.0082 | 44697 |
[ |
TIF1, TIF2 | Translation initiation factor eIF4A, identical to Tif2p; DEA(D/H)-box RNA helicase that couples ATPa... | 4 | 4 | 14.7% | 0.0082 | 44697 |
[ |
SSC1 | Hsp70 family ATPase, constituent of the import motor component of the Translocase of the Inner Mitoc... | 4 | 4 | 7.6% | 0.00495 | 70628 |
[ |
PSF3 | Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p), which is localized to DNA replication orig... | 3 | 6 | 21.2% | 0.0206 | 27096 |
[ |
BMH2 | 14-3-3 protein, minor isoform; controls proteome at post-transcriptional level, binds proteins and D... | 3 | 3 | 12.8% | 0.0089 | 31061 |
[ |
PDI1 | Protein disulfide isomerase, multifunctional protein resident in the endoplasmic reticulum lumen, es... | 3 | 3 | 10.0% | 0.00466 | 58227 |
[ |
SSZ1 | Hsp70 protein that interacts with Zuo1p (a DnaJ homolog) to form a ribosome-associated complex that ... | 3 | 4 | 9.8% | 0.00566 | 62186 |
[ |
SSA4 | Heat shock protein that is highly induced upon stress; plays a role in SRP-dependent cotranslational... | 3 | 14 | 8.1% | 0.0177 | 69651 |
[ |
PGI1 | Glycolytic enzyme phosphoglucose isomerase, catalyzes the interconversion of glucose-6-phosphate and... | 3 | 4 | 8.1% | 0.00585 | 61299 |
[ |
YEF3 | Translational elongation factor 3, stimulates the binding of aminoacyl-tRNA (AA-tRNA) to ribosomes b... | 3 | 3 | 5.2% | 0.00233 | 115945 |
[ |
RPP2B | Ribosomal protein P2 beta, a component of the ribosomal stalk, which is involved in the interaction ... | 2 | 2 | 22.7% | 0.0147 | 11050 |
[ |
CPR1 | Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization... | 2 | 5 | 21.0% | 0.025 | 17391 |
[ |
SNU13 | RNA binding protein, part of U3 snoRNP involved in rRNA processing, part of U4/U6-U5 tri-snRNP invol... | 2 | 2 | 19.0% | 0.0129 | 13569 |
[ |
EFB1 | Translation elongation factor 1 beta; stimulates nucleotide exchange to regenerate EF-1 alpha-GTP fo... | 2 | 2 | 13.6% | 0.00786 | 22627 |
[ |
IPP1 | Cytoplasmic inorganic pyrophosphatase (PPase), homodimer that catalyzes the rapid exchange of oxygen... | 2 | 2 | 11.8% | 0.00564 | 32300 |
[ |
TAL1 | Transaldolase, enzyme in the non-oxidative pentose phosphate pathway; converts sedoheptulose 7-phosp... | 2 | 3 | 10.4% | 0.00725 | 37036 |
[ |
IMD1 | [DUBIOUS] Nonfunctional protein with homology to IMP dehydrogenase; probable pseudogene, located clo... | 2 | 3 | 9.4% | 0.00603 | 44386 |
[ |
BMH1 | 14-3-3 protein, major isoform; controls proteome at post-transcriptional level, binds proteins and D... | 2 | 2 | 8.6% | 0.00607 | 30091 |
[ |
IMD3 | Inosine monophosphate dehydrogenase, catalyzes the first step of GMP biosynthesis, member of a four-... | 2 | 3 | 7.3% | 0.00465 | 56585 |
[ |
IMD2 | Inosine monophosphate dehydrogenase, catalyzes the rate-limiting step in GTP biosynthesis, expressio... | 2 | 3 | 7.3% | 0.00465 | 56530 |
[ |
ADE17 | Enzyme of 'de novo' purine biosynthesis containing both 5-aminoimidazole-4-carboxamide ribonucleotid... | 2 | 2 | 6.4% | 0.00274 | 65263 |
[ |
GDH1 | NADP(+)-dependent glutamate dehydrogenase, synthesizes glutamate from ammonia and alpha-ketoglutarat... | 2 | 2 | 5.9% | 0.00357 | 49570 |
[ |
GND1 | 6-phosphogluconate dehydrogenase (decarboxylating), catalyzes an NADPH regenerating reaction in the ... | 2 | 2 | 5.7% | 0.00331 | 53543 |
[ |
PDC6 | Minor isoform of pyruvate decarboxylase, decarboxylates pyruvate to acetaldehyde, involved in amino ... | 2 | 9 | 5.0% | 0.0129 | 61581 |
[ |
PFK1 | Alpha subunit of heterooctameric phosphofructokinase involved in glycolysis, indispensable for anaer... | 2 | 6 | 4.3% | 0.00492 | 107970 |
[ |
UBI4 | Ubiquitin, becomes conjugated to proteins, marking them for selective degradation via the ubiquitin-... | 2 | 15 | 3.9% | 0.0319 | 42826 |
[ |
YME2 | Integral inner mitochondrial membrane protein with a role in maintaining mitochondrial nucleoid stru... | 2 | 2 | 3.9% | 0.00191 | 96689 |
[ |
KAR2 | ATPase involved in protein import into the ER, also acts as a chaperone to mediate protein folding i... | 2 | 3 | 3.8% | 0.00356 | 74468 |
[ |
PYK2 | Pyruvate kinase that appears to be modulated by phosphorylation; PYK2 transcription is repressed by ... | 2 | 2 | 2.0% | 0.0032 | 55195 |