From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
Notes: | Classifier used Gene Ontology annotations. [FDR: 0.069] [SVM Score: 0.847113984121] |
Complex Size: | 2 proteins |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
Dbf4-dependent protein kinase complex | 6.3568E-4 | 2 | 2 | 1 | 6292 |
origin recognition complex | 1.9064E-3 | 2 | 6 | 1 | 6292 |
nuclear origin of replication recognition complex | 1.9064E-3 | 2 | 6 | 1 | 6292 |
pre-replicative complex | 5.0798E-3 | 2 | 16 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
DNA replication initiation | 2.6678E-5 | 2 | 33 | 2 | 6292 |
DNA-dependent DNA replication | 1.678E-4 | 2 | 82 | 2 | 6292 |
DNA replication | 3.791E-4 | 2 | 123 | 2 | 6292 |
positive regulation of protein kinase activity | 2.5415E-3 | 2 | 8 | 1 | 6292 |
positive regulation of kinase activity | 2.5415E-3 | 2 | 8 | 1 | 6292 |
positive regulation of transferase activity | 2.5415E-3 | 2 | 8 | 1 | 6292 |
pre-replicative complex assembly | 4.1283E-3 | 2 | 13 | 1 | 6292 |
positive regulation of molecular function | 5.0798E-3 | 2 | 16 | 1 | 6292 |
positive regulation of catalytic activity | 5.0798E-3 | 2 | 16 | 1 | 6292 |
regulation of cellular metabolic process | 7.2445E-3 | 2 | 536 | 2 | 6292 |
regulation of metabolic process | 7.5452E-3 | 2 | 547 | 2 | 6292 |
regulation of kinase activity | 8.248E-3 | 2 | 26 | 1 | 6292 |
regulation of protein kinase activity | 8.248E-3 | 2 | 26 | 1 | 6292 |
regulation of transferase activity | 8.248E-3 | 2 | 26 | 1 | 6292 |
DNA metabolic process | 8.631E-3 | 2 | 585 | 2 | 6292 |
regulation of phosphorylation | 9.8303E-3 | 2 | 31 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
DNA replication origin binding | 3.9411E-6 | 2 | 13 | 2 | 6292 |
sequence-specific DNA binding | 6.1895E-5 | 2 | 50 | 2 | 6292 |
protein serine/threonine kinase activator activity | 6.3568E-4 | 2 | 2 | 1 | 6292 |
DNA binding | 1.6492E-3 | 2 | 256 | 2 | 6292 |
protein kinase activator activity | 2.859E-3 | 2 | 9 | 1 | 6292 |
kinase activator activity | 3.1764E-3 | 2 | 10 | 1 | 6292 |