From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
Notes: | Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 1.02717165341] |
Complex Size: | 2 proteins |
Protein |
GO Cellular Component | GO Biological Process | GO Molecular Function |
BFA1 |
|
|
|
BUB2 |
|
|
|
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
microtubule organizing center | 9.8679E-5 | 2 | 63 | 2 | 6292 |
spindle pole body | 9.8679E-5 | 2 | 63 | 2 | 6292 |
spindle pole | 1.151E-4 | 2 | 68 | 2 | 6292 |
spindle | 1.9786E-4 | 2 | 89 | 2 | 6292 |
microtubule cytoskeleton | 2.8118E-4 | 2 | 106 | 2 | 6292 |
cytoskeletal part | 1.0156E-3 | 2 | 201 | 2 | 6292 |
cytoskeleton | 1.1732E-3 | 2 | 216 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
mitotic cell cycle spindle orientation checkpoint | 3.0316E-7 | 2 | 4 | 2 | 6292 |
regulation of exit from mitosis | 1.5158E-5 | 2 | 25 | 2 | 6292 |
mitotic cell cycle spindle checkpoint | 1.5158E-5 | 2 | 25 | 2 | 6292 |
exit from mitosis | 1.5158E-5 | 2 | 25 | 2 | 6292 |
spindle checkpoint | 1.5158E-5 | 2 | 25 | 2 | 6292 |
mitotic cell cycle checkpoint | 1.9099E-5 | 2 | 28 | 2 | 6292 |
cell cycle checkpoint | 8.3521E-5 | 2 | 58 | 2 | 6292 |
regulation of mitotic cell cycle | 1.2556E-4 | 2 | 71 | 2 | 6292 |
regulation of cell cycle process | 1.6371E-4 | 2 | 81 | 2 | 6292 |
M phase of mitotic cell cycle | 4.1068E-4 | 2 | 128 | 2 | 6292 |
regulation of cell cycle | 4.3024E-4 | 2 | 131 | 2 | 6292 |
signal transduction | 1.1516E-3 | 2 | 214 | 2 | 6292 |
signaling process | 1.1841E-3 | 2 | 217 | 2 | 6292 |
signal transmission | 1.1841E-3 | 2 | 217 | 2 | 6292 |
signaling | 1.598E-3 | 2 | 252 | 2 | 6292 |
mitotic cell cycle | 1.6363E-3 | 2 | 255 | 2 | 6292 |
M phase | 2.1762E-3 | 2 | 294 | 2 | 6292 |
cell cycle phase | 3.5621E-3 | 2 | 376 | 2 | 6292 |
cell cycle process | 6.0534E-3 | 2 | 490 | 2 | 6292 |
cell cycle | 6.95E-3 | 2 | 525 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
GTPase activator activity | 2.5061E-5 | 2 | 32 | 2 | 6292 |
enzyme activator activity | 1.1171E-4 | 2 | 67 | 2 | 6292 |
GTPase regulator activity | 1.7614E-4 | 2 | 84 | 2 | 6292 |
nucleoside-triphosphatase regulator activity | 2.256E-4 | 2 | 95 | 2 | 6292 |
enzyme regulator activity | 1.0773E-3 | 2 | 207 | 2 | 6292 |