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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 1.18447783698]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
SEN15
  • nuclear inner membrane
  • tRNA-intron endonuclease complex
  • mitochondrial outer membrane
    		•
  • tRNA splicing, via endonucleolytic cleavage and ligation
    		•
  • tRNA-intron endonuclease activity
    		•
    SEN2
  • nuclear inner membrane
  • mitochondrion
  • tRNA-intron endonuclease complex
  • mitochondrial outer membrane
    		•
  • tRNA splicing, via endonucleolytic cleavage and ligation
    		•
  • tRNA-intron endonuclease activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    tRNA-intron endonuclease complex 5.0527E-7 2 5 2 6292
    nuclear inner membrane 2.779E-6 2 11 2 6292
    mitochondrial outer membrane 2.1151E-4 2 92 2 6292
    nuclear membrane 2.3525E-4 2 97 2 6292
    outer membrane 7.9595E-4 2 178 2 6292
    organelle outer membrane 7.9595E-4 2 178 2 6292
    organelle inner membrane 8.5997E-4 2 185 2 6292
    nuclear envelope 9.9543E-4 2 199 2 6292
    mitochondrial membrane 1.7808E-3 2 266 2 6292
    mitochondrial envelope 2.4514E-3 2 312 2 6292
    endomembrane system 3.9918E-3 2 398 2 6292
    mitochondrial part 5.6881E-3 2 475 2 6292
    envelope 6.43E-3 2 505 2 6292
    organelle envelope 6.43E-3 2 505 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    tRNA splicing, via endonucleolytic cleavage and ligation 6.0632E-6 2 16 2 6292
    RNA splicing, via endonucleolytic cleavage and ligation 6.0632E-6 2 16 2 6292
    tRNA processing 1.7194E-4 2 83 2 6292
    tRNA metabolic process 3.6076E-4 2 120 2 6292
    RNA splicing 4.3685E-4 2 132 2 6292
    ncRNA processing 1.1624E-3 2 215 2 6292
    ncRNA metabolic process 1.6621E-3 2 257 2 6292
    RNA processing 3.6384E-3 2 380 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    tRNA-intron endonuclease activity 5.0527E-7 2 5 2 6292
    endoribonuclease activity, producing 3'-phosphomonoesters 5.0527E-7 2 5 2 6292
    endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1.819E-6 2 9 2 6292
    tRNA-specific ribonuclease activity 5.3053E-6 2 15 2 6292
    endoribonuclease activity 1.7735E-5 2 27 2 6292
    endonuclease activity 9.2464E-5 2 61 2 6292
    ribonuclease activity 5.5711E-4 2 149 2 6292
    nuclease activity 9.9543E-4 2 199 2 6292
    hydrolase activity, acting on ester bonds 2.929E-3 2 341 2 6292
    YRC Informatics Platform - Version 3.0
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