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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Gcd2. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 6 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

eukaryotic translation initiation factor 2B complex 7.3127E-17 6 5 5 6292
guanyl-nucleotide exchange factor complex 1.5353E-15 6 7 5 6292
protein complex 9.756E-4 6 1137 5 6292
macromolecular complex 5.5477E-3 6 1635 5 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

regulation of translational initiation 3.3758E-14 6 11 5 6292
translational initiation 6.1902E-11 6 42 5 6292
regulation of translation 3.0408E-10 6 57 5 6292
posttranscriptional regulation of gene expression 4.3182E-10 6 61 5 6292
regulation of cellular protein metabolic process 7.5592E-10 6 68 5 6292
regulation of protein metabolic process 1.1672E-9 6 74 5 6292
regulation of gene expression 1.2127E-7 6 445 6 6292
regulation of macromolecule biosynthetic process 1.4052E-7 6 456 6 6292
regulation of cellular biosynthetic process 1.7302E-7 6 472 6 6292
regulation of biosynthetic process 1.7524E-7 6 473 6 6292
regulation of macromolecule metabolic process 2.1155E-7 6 488 6 6292
regulation of primary metabolic process 2.8931E-7 6 514 6 6292
regulation of cellular metabolic process 3.7247E-7 6 536 6 6292
regulation of metabolic process 4.21E-7 6 547 6 6292
regulation of cellular process 4.0325E-6 6 796 6 6292
translation 4.2398E-6 6 376 5 6292
regulation of biological process 4.9653E-6 6 824 6 6292
cellular macromolecule biosynthetic process 4.4618E-5 6 1187 6 6292
macromolecule biosynthetic process 4.5072E-5 6 1189 6 6292
biological regulation 5.0826E-5 6 1213 6 6292
gene expression 7.1216E-5 6 1283 6 6292
cellular biosynthetic process 2.3689E-4 6 1567 6 6292
biosynthetic process 2.7052E-4 6 1602 6 6292
cellular protein metabolic process 7.4048E-4 6 1074 5 6292
protein metabolic process 9.7146E-4 6 1136 5 6292
cellular macromolecule metabolic process 2.2844E-3 6 2285 6 6292
macromolecule metabolic process 2.6967E-3 6 2349 6 6292
nucleosome positioning 2.8585E-3 6 3 1 6292
primary metabolic process 9.4808E-3 6 2896 6 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

translation initiation factor activity 5.8863E-12 6 27 5 6292
guanyl-nucleotide exchange factor activity 3.6545E-11 6 38 5 6292
translation factor activity, nucleic acid binding 7.9006E-11 6 44 5 6292
GTPase regulator activity 2.2339E-9 6 84 5 6292
nucleoside-triphosphatase regulator activity 4.1865E-9 6 95 5 6292
enzyme regulator activity 2.147E-7 6 207 5 6292
nucleic acid binding 7.1765E-5 6 666 5 6292
binding 1.819E-3 6 1294 5 6292
general transcriptional repressor activity 1.9064E-3 6 2 1 6292

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