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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Rck1. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 7 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
FUS3
  • nucleus
  • cytoplasm
  • mitochondrion
  • mating projection tip
  • cell cycle arrest
  • invasive growth in response to glucose limitation
  • signal transduction during filamentous growth
  • protein amino acid phosphorylation
  • pheromone-dependent signal transduction involved in conjugation with cellular fusion
  • MAP kinase activity
  • HOG1
  • nucleus
  • cytoplasm
  • negative regulation of transcription from RNA polymerase II promoter by pheromones
  • osmosensory signaling pathway
  • response to arsenic
  • protein amino acid phosphorylation
  • positive regulation of transcription from RNA polymerase II promoter
  • hyperosmotic response
  • MAP kinase activity
  • IDH2
  • mitochondrial matrix
  • mitochondrion
  • glutamate biosynthetic process
  • isocitrate metabolic process
  • tricarboxylic acid cycle
  • isocitrate dehydrogenase (NAD+) activity
  • RCK1
  • cellular_component
  • regulation of meiosis
  • protein amino acid phosphorylation
  • protein serine/threonine kinase activity
  • ROD1
  • plasma membrane
  • response to drug
  • molecular_function
  • RPN8
  • proteasome regulatory particle, lid subcomplex
  • ubiquitin-dependent protein catabolic process
  • molecular_function
  • SNF1
  • nucleus
  • cytoplasm
  • mitochondrion
  • fungal-type vacuole
  • nuclear envelope lumen
  • AMP-activated protein kinase complex
  • regulation of carbohydrate metabolic process
  • signal transduction
  • pseudohyphal growth
  • cell adhesion
  • invasive growth in response to glucose limitation
  • protein amino acid phosphorylation
  • replicative cell aging
  • biofilm formation
  • positive regulation of gluconeogenesis
  • cellular response to nitrogen starvation
  • AMP-activated protein kinase activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    nuclear envelope lumen 4.4437E-3 7 4 1 6292
    AMP-activated protein kinase complex 6.6592E-3 7 6 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    protein amino acid phosphorylation 2.2834E-6 7 103 4 6292
    phosphorylation 2.0738E-5 7 179 4 6292
    phosphorus metabolic process 5.4882E-5 7 229 4 6292
    phosphate metabolic process 5.4882E-5 7 229 4 6292
    post-translational protein modification 3.1112E-4 7 357 4 6292
    invasive growth in response to glucose limitation 1.1199E-3 7 47 2 6292
    protein modification process 1.1271E-3 7 499 4 6292
    macromolecule modification 1.8549E-3 7 569 4 6292
    signaling 1.9711E-3 7 252 3 6292
    cellular response to nitrogen levels 2.224E-3 7 2 1 6292
    cellular response to nitrogen starvation 2.224E-3 7 2 1 6292
    cellular protein metabolic process 2.2261E-3 7 1074 5 6292
    protein metabolic process 2.8929E-3 7 1136 5 6292
    filamentous growth of a population of unicellular organisms 4.0554E-3 7 90 2 6292
    growth of unicellular organism as a thread of attached cells 4.0554E-3 7 90 2 6292
    positive regulation of gluconeogenesis 4.4437E-3 7 4 1 6292
    negative regulation of transcription from RNA polymerase II promoter by pheromones 4.4437E-3 7 4 1 6292
    negative regulation of gene-specific transcription from RNA polymerase II promoter 4.4437E-3 7 4 1 6292
    negative regulation of gene-specific transcription 4.4437E-3 7 4 1 6292
    negative regulation of transcription by pheromones 4.4437E-3 7 4 1 6292
    response to pheromone 4.6971E-3 7 97 2 6292
    isocitrate metabolic process 5.552E-3 7 5 1 6292
    filamentous growth 5.5873E-3 7 106 2 6292
    response to stimulus 5.631E-3 7 766 4 6292
    cellular response to chemical stimulus 5.6907E-3 7 107 2 6292
    cellular response to stimulus 6.3249E-3 7 379 3 6292
    response to chemical stimulus 6.4671E-3 7 382 3 6292
    regulation of cellular process 6.4862E-3 7 796 4 6292
    biofilm formation 6.6592E-3 7 6 1 6292
    positive regulation of biosynthetic process 7.231E-3 7 121 2 6292
    positive regulation of cellular biosynthetic process 7.231E-3 7 121 2 6292
    regulation of biological process 7.3628E-3 7 824 4 6292
    positive regulation of metabolic process 8.188E-3 7 129 2 6292
    positive regulation of cellular metabolic process 8.188E-3 7 129 2 6292
    biological adhesion 8.8705E-3 7 8 1 6292
    positive regulation of glucose metabolic process 8.8705E-3 7 8 1 6292
    cell adhesion 8.8705E-3 7 8 1 6292
    positive regulation of cellular carbohydrate metabolic process 8.8705E-3 7 8 1 6292
    signal transduction during filamentous growth 8.8705E-3 7 8 1 6292
    positive regulation of carbohydrate metabolic process 8.8705E-3 7 8 1 6292
    positive regulation of cellular process 9.0704E-3 7 136 2 6292
    positive regulation of biological process 9.1999E-3 7 137 2 6292
    response to organic substance 9.1999E-3 7 137 2 6292
    response to arsenic 9.9746E-3 7 9 1 6292
    multi-organism process 9.9944E-3 7 143 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    protein serine/threonine kinase activity 1.3867E-6 7 91 4 6292
    MAP kinase activity 1.0594E-5 7 5 2 6292
    protein kinase activity 1.2011E-5 7 156 4 6292
    phosphotransferase activity, alcohol group as acceptor 3.0919E-5 7 198 4 6292
    kinase activity 4.8566E-5 7 222 4 6292
    transferase activity, transferring phosphorus-containing groups 5.8266E-4 7 420 4 6292
    receptor signaling protein serine/threonine kinase activity 6.5652E-4 7 36 2 6292
    receptor signaling protein activity 6.9367E-4 7 37 2 6292
    isocitrate dehydrogenase (NAD+) activity 2.224E-3 7 2 1 6292
    molecular transducer activity 3.2169E-3 7 80 2 6292
    signal transducer activity 3.2169E-3 7 80 2 6292
    isocitrate dehydrogenase activity 5.552E-3 7 5 1 6292
    transferase activity 6.5162E-3 7 797 4 6292
    AMP-activated protein kinase activity 6.6592E-3 7 6 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle