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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Yfr016c. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 5 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

F-actin capping protein complex 5.0527E-7 5 2 2 6292
actin cortical patch 2.5457E-6 5 41 3 6292
cortical actin cytoskeleton 5.2637E-6 5 52 3 6292
cortical cytoskeleton 5.2637E-6 5 52 3 6292
actin filament 1.8149E-5 5 9 2 6292
actin cytoskeleton 2.3339E-5 5 85 3 6292
cell cortex part 3.3673E-5 5 96 3 6292
cell cortex 4.9321E-5 5 109 3 6292
cytoskeletal part 3.0632E-4 5 201 3 6292
cytoskeleton 3.7915E-4 5 216 3 6292
non-membrane-bounded organelle 2.3579E-3 5 959 4 6292
intracellular non-membrane-bounded organelle 2.3579E-3 5 959 4 6292
mitochondrial oxoglutarate dehydrogenase complex 2.3825E-3 5 3 1 6292
oxoglutarate dehydrogenase complex 2.3825E-3 5 3 1 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

actin filament depolymerization 9.6371E-10 5 4 3 6292
actin polymerization or depolymerization 2.0214E-8 5 9 3 6292
protein depolymerization 2.887E-8 5 10 3 6292
barbed-end actin filament capping 5.0527E-7 5 2 2 6292
actin filament capping 5.0527E-7 5 2 2 6292
negative regulation of actin filament depolymerization 5.0527E-7 5 2 2 6292
regulation of actin filament depolymerization 5.0527E-7 5 2 2 6292
regulation of actin polymerization or depolymerization 1.5153E-6 5 3 2 6292
protein polymerization 1.5153E-6 5 3 2 6292
regulation of actin cytoskeleton organization 1.5153E-6 5 3 2 6292
regulation of protein polymerization 1.5153E-6 5 3 2 6292
negative regulation of protein polymerization 1.5153E-6 5 3 2 6292
negative regulation of protein complex assembly 1.5153E-6 5 3 2 6292
actin filament polymerization 1.5153E-6 5 3 2 6292
regulation of actin filament polymerization 1.5153E-6 5 3 2 6292
regulation of actin filament length 1.5153E-6 5 3 2 6292
negative regulation of actin filament polymerization 1.5153E-6 5 3 2 6292
regulation of actin filament-based process 1.5153E-6 5 3 2 6292
cellular protein complex disassembly 2.1835E-6 5 39 3 6292
protein complex disassembly 2.1835E-6 5 39 3 6292
cellular macromolecular complex disassembly 2.36E-6 5 40 3 6292
macromolecular complex disassembly 2.36E-6 5 40 3 6292
cellular component disassembly 3.1605E-6 5 44 3 6292
negative regulation of protein complex disassembly 1.0594E-5 5 7 2 6292
actin filament organization 1.1891E-5 5 68 3 6292
negative regulation of cytoskeleton organization 1.4121E-5 5 8 2 6292
regulation of protein complex disassembly 2.2679E-5 5 10 2 6292
regulation of protein complex assembly 2.771E-5 5 11 2 6292
actin cytoskeleton organization 5.4953E-5 5 113 3 6292
actin filament-based process 6.0995E-5 5 117 3 6292
regulation of cellular component biogenesis 7.6913E-5 5 18 2 6292
regulation of cytoskeleton organization 9.5453E-5 5 20 2 6292
negative regulation of cellular component organization 2.0338E-4 5 29 2 6292
negative regulation of organelle organization 2.0338E-4 5 29 2 6292
cytoskeleton organization 4.6248E-4 5 231 3 6292
cellular macromolecular complex subunit organization 6.4832E-4 5 259 3 6292
regulation of organelle organization 6.594E-4 5 52 2 6292
cellular protein complex assembly 7.1116E-4 5 54 2 6292
actin filament severing 7.9466E-4 5 1 1 6292
regulation of cellular component organization 1.3699E-3 5 75 2 6292
2-oxoglutarate metabolic process 1.5888E-3 5 2 1 6292
macromolecular complex subunit organization 1.6626E-3 5 357 3 6292
regulation of anatomical structure size 3.1401E-3 5 114 2 6292
regulation of cellular component size 3.1401E-3 5 114 2 6292
protein complex biogenesis 5.7423E-3 5 155 2 6292
protein complex assembly 5.7423E-3 5 155 2 6292
cellular macromolecular complex assembly 7.856E-3 5 182 2 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

actin filament binding 3.3242E-5 5 12 2 6292
actin binding 1.0547E-4 5 21 2 6292
cytoskeletal protein binding 8.4895E-4 5 59 2 6292
oxoglutarate dehydrogenase (succinyl-transferring) activity 1.5888E-3 5 2 1 6292
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor 3.9682E-3 5 5 1 6292
protein binding 7.8822E-3 5 612 3 6292

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