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The aggregation, arrangement and bonding together of a proton-transporting two-sector ATPase complex, a large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane. The cell cycle process whereby aggregation, arrangement and bonding together of a set of components to form the spindle midzone. The spindle midzone is the area in the center of the spindle where the spindle microtubules from opposite poles overlap. The process of creating protein polymers, compounds composed of a large number of component monomers; polymeric proteins may be made up of different or identical monomers. Polymerization occurs by the addition of extra monomers to an existing poly- or oligomeric protein. The aggregation, arrangement and bonding together of the nuclear localization signal of a protein with nuclear envelope proteins such as importins. The cellular process by which a protein complex is synthesized, aggregates, and bonds together. Includes the synthesis of the constituent protein molecules, and those protein modifications that are involved in synthesis or assembly of the complex. The aggregation, arrangement and bonding together of a set of components to form a protein complex, occurring at the level of an individual cell. The binding of specific proteins to the t-SNARE/v-SNARE/SNAP25 complex, by which the Golgi vesicle prefusion complex is stabilized. Any process that initiates the activity of the inactive transmembrane receptor protein tyrosine kinase activity. The aggregation, arrangement and bonding together of a set of components to form a complex capable of relaying a signal within a cell. Complex formation involves dimerization of a receptor protein tyrosine kinase followed by the association of several different intracellular signaling molecules with the cytoplasmic tails of the receptors. The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex II. The aggregation, arrangement and bonding together of a set of components to form a signalosome. The aggregation, arrangement and bonding together of a set of components to form a mitochondrial outer membrane translocase complex. The aggregation, arrangement and bonding together of a set of macromolecules to form a complex. The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein complex, a dynein complex found in eukaryotic cilia and flagella, in which the motor domain heads interact with adjacent microtubules to generate a sliding force which is converted to a bending motion. The aggregation, arrangement and bonding together of a protein structure comprising two or more rings that are interlocked but not covalently joined; resembling the links of a chain. The aggregation, arrangement and bonding together of a set of components to form a protein complex that contains SMAD proteins. The aggregation, arrangement and bonding together of septins and associated proteins to form an organized structure resembling a ring at the cell cortex. The aggregation, arrangement and bonding together of a ligand-bound type II transforming growth factor beta (TGF-beta) receptor dimer with a type I TGF-beta receptor dimer, following ligand binding, to form a heterotetrameric TGF-beta receptor complex. The aggregation, arrangement and bonding together of a filament composed of myosin molecules. The aggregation, arrangement and bonding together of a set of components to form a mitochondrial respiratory chain complex. The aggregation, arrangement and bonding together of a set of components to form a photosystem II complex on thylakoid membrane. In plants, the photosystem II complex consists of over 20 polypeptides encoded by either nuclear or chloroplast genome. The aggregation, arrangement and bonding together of a set of components to form a SNARE complex, a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. The formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion. The formation of a protein complex between the coat proteins and proteins that are going to be transported by a vesicle. The process by which a complex formed of a peroxisome targeting sequence (PTS) receptor bound to a PTS-bearing protein docks with translocation machinery in the preoxisomal membrane. The aggregation, arrangement and bonding together of a set of components to form an eisosome, a large immobile protein complex that forms at the plasma membrane and marks endocytic sites. The formation of a dimer of two STAT proteins (Signal Transducers and Activators of Transcription) following their activation by members of the janus activated kinase (JAK) family of tyrosine kinases. The aggregation, arrangement and bonding together of a set of components to form a nuclear pore complex. The aggregation, arrangement and bonding together of a set of components to form an NADH dehydrogenase complex. The process by which the signal sequence of a translated protein binds to and forms a complex with the Sec complex. The aggregation, arrangement and bonding together of a mature, active proteasome complex. The aggregation, arrangement and bonding together of a set of components to form the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules. The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase), the terminal member of the respiratory chain of the mitochondrion and some aerobic bacteria. Cytochrome c oxidases are multi-subunit enzymes containing from 13 subunits in the mammalian mitochondrial form to 3-4 subunits in the bacterial forms. The aggregation, arrangement and bonding together of various polypeptides into the exocyst complex. The aggregation, arrangement and bonding together of a set of components to form the eukaryotic translation initiation factor 3 complex. The aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex. Any process carried out at the cellular level by which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a macromolecular complex. The aggregation, arrangement and bonding together of a set of macromolecules to form a complex, carried out at the cellular level. The binding of a peptide to the antigen binding groove of an MHC protein complex. The process by which SRP binds to the signal peptide in a nascent protein, causing protein elongation to pause, during cotranslational membrane targeting. The aggregation, arrangement and bonding together of a set of components to form a photosystem I complex on the thylakoid membrane. Cellular protein complex assembly that results in the formation of a voltage-gated calcium channel complex. The aggregation, arrangement and bonding together of a set of components to form the SKP1-Cullin/Cdc53-F-box protein ubiquitin ligase (SCF) complex. The aggregation, arrangement and bonding together of a set of components to form an MHC protein complex. The aggregation, arrangement and bonding together of a set of components to form a protein complex. The aggregation, arrangement and bonding together of a set of components to form NAD(P)H dehydrogenase complex, which is involved in electron transport from an unidentified electron donor, possibly NAD(P)H or ferredoxin(Fd) to the plastoquinone pool. The aggregation, arrangement and bonding together of a set of components to form a transcription factor TFIIIB complex. The aggregation and bonding together of alpha- and beta-tubulin to form a tubulin heterodimer. The aggregation, arrangement and bonding together of priming complexes to form a coat on a Golgi membrane. Priming complexes associate laterally and additional coat proteins are recruited from the cytosol to the forming coat. Cargo proteins diffuse into the budding site and become trapped by their interactions with the coat. The aggregation, arrangement and bonding together of a set of components to form a membrane priming complex. An incoming coat component recognizes both GTPase and a membrane protein to form the priming complex. The aggregation, arrangement and bonding together of a cytochrome complex. A cytochrome complex is a protein complex in which at least one of the proteins is a cytochrome, i.e. a heme-containing protein involved in catalysis of redox reactions. The aggregation, arrangement and bonding together of a set of components to form a steroid hormone receptor complex, an intracellular receptor that binds steroid hormones. The complex is often a dimer, and forms after the steroid has bound the receptor. The aggregation, arrangement and bonding together of a set of components to form a GINS complex, a heterotetrameric protein complex that associates with DNA replication origins and replication forks. The process by which clathrin triskelia are assembled into the ordered structure known as a clathrin cage.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: cellular protein complex assembly
Acc: GO:0043623
Aspect: Biological Process
Desc: The aggregation, arrangement and bonding together of a set of components to form a protein complex, occurring at the level of an individual cell.
Proteins in PDR annotated with:
   This term: 20 [Search]
   Term or descendants: 1147 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0043623 - cellular protein complex assembly (interactive image map)

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Created and Maintained by: Michael Riffle