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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Pbs2. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 3 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

cellular bud tip 2.4051E-4 3 57 2 6292
cellular bud neck 1.2346E-3 3 129 2 6292
cellular bud 2.0398E-3 3 166 2 6292
site of polarized growth 2.089E-3 3 168 2 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

positive regulation of protein kinase activity 4.2416E-6 3 8 2 6292
positive regulation of kinase activity 4.2416E-6 3 8 2 6292
positive regulation of transferase activity 4.2416E-6 3 8 2 6292
MAPKKK cascade involved in osmosensory signaling pathway 1.1809E-5 3 13 2 6292
positive regulation of catalytic activity 1.8163E-5 3 16 2 6292
positive regulation of molecular function 1.8163E-5 3 16 2 6292
osmosensory signaling pathway 3.1768E-5 3 21 2 6292
MAPKKK cascade 3.1768E-5 3 21 2 6292
cellular response to abiotic stimulus 3.4941E-5 3 22 2 6292
cellular response to osmotic stress 3.4941E-5 3 22 2 6292
intracellular protein kinase cascade 4.1739E-5 3 24 2 6292
signal transmission via phosphorylation event 4.1739E-5 3 24 2 6292
regulation of kinase activity 4.9138E-5 3 26 2 6292
regulation of protein kinase activity 4.9138E-5 3 26 2 6292
regulation of transferase activity 4.9138E-5 3 26 2 6292
regulation of phosphorylation 7.0268E-5 3 31 2 6292
regulation of phosphate metabolic process 1.0615E-4 3 38 2 6292
regulation of phosphorus metabolic process 1.0615E-4 3 38 2 6292
regulation of catalytic activity 1.4276E-4 3 44 2 6292
regulation of molecular function 1.4276E-4 3 44 2 6292
response to osmotic stress 4.4E-4 3 77 2 6292
activation of MAPK activity 4.768E-4 3 1 1 6292
nuclear translocation of MAPK 4.768E-4 3 1 1 6292
positive regulation of MAP kinase activity 4.768E-4 3 1 1 6292
low-affinity iron ion transport 4.768E-4 3 1 1 6292
nuclear translocation of MAPK involved in osmosensory signaling pathway 4.768E-4 3 1 1 6292
activation of MAPK activity involved in osmosensory signaling pathway 4.768E-4 3 1 1 6292
protein amino acid phosphorylation 7.8773E-4 3 103 2 6292
actin cytoskeleton organization 9.4792E-4 3 113 2 6292
intracellular signal transduction 9.8171E-4 3 115 2 6292
actin filament-based process 1.0161E-3 3 117 2 6292
response to abiotic stimulus 1.0161E-3 3 117 2 6292
protein import into nucleus, translocation 1.4299E-3 3 3 1 6292
activation of MAPKK activity involved in osmosensory signaling pathway 1.4299E-3 3 3 1 6292
intracellular signaling pathway 1.5372E-3 3 144 2 6292
phosphorylation 2.3695E-3 3 179 2 6292
activation of MAPKK activity 2.3825E-3 3 5 1 6292
intracellular copper ion transport 2.3825E-3 3 5 1 6292
activation of protein kinase activity 2.3825E-3 3 5 1 6292
iron ion transmembrane transport 2.3825E-3 3 5 1 6292
signaling pathway 2.5028E-3 3 184 2 6292
copper ion transmembrane transport 2.8585E-3 3 6 1 6292
copper ion import 2.8585E-3 3 6 1 6292
regulation of MAP kinase activity 2.8585E-3 3 6 1 6292
signal transduction 3.377E-3 3 214 2 6292
signal transmission 3.4715E-3 3 217 2 6292
signaling process 3.4715E-3 3 217 2 6292
regulation of signal transduction 3.8101E-3 3 8 1 6292
regulation of signaling process 3.8101E-3 3 8 1 6292
phosphorus metabolic process 3.8619E-3 3 229 2 6292
phosphate metabolic process 3.8619E-3 3 229 2 6292
cytoskeleton organization 3.929E-3 3 231 2 6292
signaling 4.6669E-3 3 252 2 6292
hyperosmotic response 4.7611E-3 3 10 1 6292
copper ion transport 5.7116E-3 3 12 1 6292
cellular response to stress 6.1581E-3 3 290 2 6292
regulation of cell communication 6.6614E-3 3 14 1 6292
iron ion transport 8.5592E-3 3 18 1 6292
post-translational protein modification 9.2699E-3 3 357 2 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

MAP-kinase scaffold activity 9.5344E-4 3 2 1 6292
protein complex scaffold 9.5344E-4 3 2 1 6292
receptor signaling complex scaffold activity 9.5344E-4 3 2 1 6292
protein kinase activity 1.8027E-3 3 156 2 6292
MAP kinase kinase activity 1.9063E-3 3 4 1 6292
copper ion transmembrane transporter activity 2.3825E-3 3 5 1 6292
MAP kinase kinase kinase activity 2.8585E-3 3 6 1 6292
phosphotransferase activity, alcohol group as acceptor 2.8949E-3 3 198 2 6292
protein serine/threonine/tyrosine kinase activity 3.3344E-3 3 7 1 6292
kinase activity 3.6317E-3 3 222 2 6292
iron ion transmembrane transporter activity 5.7116E-3 3 12 1 6292

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