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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Ssk1. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 4 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

telomerase holoenzyme complex 2.5411E-3 4 4 1 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

osmosensory signaling pathway 1.2793E-7 4 21 3 6292
cellular response to abiotic stimulus 1.4811E-7 4 22 3 6292
cellular response to osmotic stress 1.4811E-7 4 22 3 6292
activation of MAPKK activity involved in osmosensory signaling pathway 9.0929E-7 4 3 2 6292
activation of MAPKK activity 3.0297E-6 4 5 2 6292
activation of protein kinase activity 3.0297E-6 4 5 2 6292
response to osmotic stress 6.989E-6 4 77 3 6292
positive regulation of protein kinase activity 8.4777E-6 4 8 2 6292
positive regulation of kinase activity 8.4777E-6 4 8 2 6292
positive regulation of transferase activity 8.4777E-6 4 8 2 6292
MAPKKK cascade involved in osmosensory signaling pathway 2.3591E-5 4 13 2 6292
response to abiotic stimulus 2.4734E-5 4 117 3 6292
positive regulation of molecular function 3.6271E-5 4 16 2 6292
positive regulation of catalytic activity 3.6271E-5 4 16 2 6292
MAPKKK cascade 6.3408E-5 4 21 2 6292
signal transmission via phosphorylation event 8.3283E-5 4 24 2 6292
intracellular protein kinase cascade 8.3283E-5 4 24 2 6292
signaling pathway 9.6331E-5 4 184 3 6292
regulation of kinase activity 9.8027E-5 4 26 2 6292
regulation of protein kinase activity 9.8027E-5 4 26 2 6292
regulation of transferase activity 9.8027E-5 4 26 2 6292
regulation of phosphorylation 1.401E-4 4 31 2 6292
signal transmission 1.5777E-4 4 217 3 6292
signaling process 1.5777E-4 4 217 3 6292
regulation of phosphorus metabolic process 2.115E-4 4 38 2 6292
regulation of phosphate metabolic process 2.115E-4 4 38 2 6292
signaling 2.465E-4 4 252 3 6292
regulation of catalytic activity 2.8424E-4 4 44 2 6292
regulation of molecular function 2.8424E-4 4 44 2 6292
cellular response to stress 3.7451E-4 4 290 3 6292
cellular response to stimulus 8.288E-4 4 379 3 6292
protein amino acid phosphorylation 1.5586E-3 4 103 2 6292
response to stress 1.8449E-3 4 497 3 6292
osmosensory signaling pathway via two-component system 1.9063E-3 4 3 1 6292
two-component signal transduction system (phosphorelay) 1.9063E-3 4 3 1 6292
intracellular signal transduction 1.9399E-3 4 115 2 6292
response to hydrogen peroxide 2.5411E-3 4 4 1 6292
intracellular signaling pathway 3.0282E-3 4 144 2 6292
phosphorylation 4.6503E-3 4 179 2 6292
response to stimulus 6.5381E-3 4 766 3 6292
signal transduction 6.6027E-3 4 214 2 6292
phosphorus metabolic process 7.5386E-3 4 229 2 6292
phosphate metabolic process 7.5386E-3 4 229 2 6292
response to reactive oxygen species 8.2408E-3 4 13 1 6292
telomere maintenance via telomere lengthening 8.2408E-3 4 13 1 6292
telomere maintenance via telomerase 8.2408E-3 4 13 1 6292
RNA-dependent DNA replication 8.2408E-3 4 13 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

MAP kinase kinase kinase activity 4.5436E-6 4 6 2 6292
molecular transducer activity 7.847E-6 4 80 3 6292
signal transducer activity 7.847E-6 4 80 3 6292
receptor signaling protein serine/threonine kinase activity 1.8962E-4 4 36 2 6292
receptor signaling protein activity 2.0041E-4 4 37 2 6292
transferase activity, transferring phosphorus-containing groups 1.123E-3 4 420 3 6292
protein serine/threonine kinase activity 1.2181E-3 4 91 2 6292
two-component response regulator activity 1.2712E-3 4 2 1 6292
telomerase activity 2.5411E-3 4 4 1 6292
protein kinase activity 3.5467E-3 4 156 2 6292
phosphotransferase activity, alcohol group as acceptor 5.6697E-3 4 198 2 6292
kinase activity 7.0945E-3 4 222 2 6292
transferase activity 7.3356E-3 4 797 3 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle