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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Bmh1. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 15 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
ADR1
  • nucleus
  • regulation of carbohydrate metabolic process
  • transcription
  • peroxisome organization
  • negative regulation of transcription from RNA polymerase II promoter by glucose
  • transcription factor activity
  • BMH1
  • nucleus
  • ascospore formation
  • DNA damage checkpoint
  • glycogen metabolic process
  • pseudohyphal growth
  • Ras protein signal transduction
  • signal transduction during filamentous growth
  • negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
  • DNA binding
  • protein binding
  • BNR1
  • cellular bud neck contractile ring
  • axial cellular bud site selection
  • response to osmotic stress
  • actin filament organization
  • cytoskeletal protein binding
  • BOI2
  • cellular bud
  • site of polarized growth
  • cellular bud neck
  • Rho protein signal transduction
  • phospholipid binding
  • CSR2
  • nucleus
  • cellular cell wall organization
  • regulation of transcription from RNA polymerase II promoter
  • molecular_function
  • CYK3
  • cytoplasm
  • cellular bud neck
  • cytokinesis
  • molecular_function
  • GSY2
  • cytoplasm
  • glycogen biosynthetic process
  • glycogen (starch) synthase activity
  • KCS1
  • cytoplasm
  • vacuole organization
  • response to drug
  • regulation of phosphate metabolic process
  • response to stress
  • inositol hexakisphosphate kinase activity
  • NTH1
  • cytoplasm
  • cytosol
  • trehalose catabolic process
  • response to stress
  • alpha,alpha-trehalase activity
  • REG1
  • protein phosphatase type 1 complex
  • cytoplasm
  • negative regulation of transcription from RNA polymerase II promoter
  • regulation of carbohydrate metabolic process
  • glycogen metabolic process
  • vacuolar protein catabolic process
  • protein phosphatase type 1 regulator activity
  • SOK1
  • nucleus
  • cAMP-mediated signaling
  • molecular_function
  • STU1
  • spindle pole body
  • microtubule nucleation
  • structural constituent of cytoskeleton
  • SVL3
  • cellular bud
  • cytoplasm
  • cellular bud neck
  • endocytosis
  • molecular_function
  • YFR017C
  • cytoplasm
  • biological_process
  • molecular_function
  • YIL028W

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cellular bud neck 1.9319E-4 15 129 4 6292
    cellular bud 5.0805E-4 15 166 4 6292
    site of polarized growth 5.317E-4 15 168 4 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    glycogen metabolic process 5.2172E-5 15 32 3 6292
    energy reserve metabolic process 5.2172E-5 15 32 3 6292
    cellular glucan metabolic process 1.2778E-4 15 43 3 6292
    glucan metabolic process 1.2778E-4 15 43 3 6292
    cellular polysaccharide metabolic process 2.67E-4 15 55 3 6292
    polysaccharide metabolic process 3.4578E-4 15 60 3 6292
    carbohydrate metabolic process 3.5576E-4 15 281 5 6292
    regulation of cellular process 1.2941E-3 15 796 7 6292
    regulation of biological process 1.5939E-3 15 824 7 6292
    glucose metabolic process 1.9772E-3 15 109 3 6292
    intracellular signal transduction 2.3055E-3 15 115 3 6292
    cellular carbohydrate metabolic process 2.7876E-3 15 262 4 6292
    hexose metabolic process 2.8586E-3 15 124 3 6292
    regulation of carbohydrate metabolic process 3.1894E-3 15 36 2 6292
    monosaccharide metabolic process 3.6382E-3 15 135 3 6292
    Ras protein signal transduction 4.1228E-3 15 41 2 6292
    intracellular signaling pathway 4.3648E-3 15 144 3 6292
    energy derivation by oxidation of organic compounds 4.8042E-3 15 149 3 6292
    regulation of cellular metabolic process 6.4295E-3 15 536 5 6292
    regulation of metabolic process 7.0111E-3 15 547 5 6292
    trehalose catabolic process 7.136E-3 15 3 1 6292
    negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 7.136E-3 15 3 1 6292
    negative regulation of protein ubiquitination 7.136E-3 15 3 1 6292
    negative regulation of ubiquitin-protein ligase activity 7.136E-3 15 3 1 6292
    negative regulation of ligase activity 7.136E-3 15 3 1 6292
    signaling pathway 8.6365E-3 15 184 3 6292
    negative regulation of transcription from RNA polymerase II promoter 8.6698E-3 15 60 2 6292
    glycoside catabolic process 9.5041E-3 15 4 1 6292
    negative regulation of protein modification process 9.5041E-3 15 4 1 6292
    negative regulation of macromolecule metabolic process 9.707E-3 15 192 3 6292
    small GTPase mediated signal transduction 9.8206E-3 15 64 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    inositol hexakisphosphate kinase activity 2.384E-3 15 1 1 6292
    glycogen (starch) synthase activity 4.7627E-3 15 2 1 6292
    trehalase activity 7.136E-3 15 3 1 6292
    alpha,alpha-trehalase activity 7.136E-3 15 3 1 6292

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    Created and Maintained by: Michael Riffle