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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Prp19. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 4 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

spliceosomal complex 1.361E-6 4 45 3 6292
ribonucleoprotein complex 2.0368E-3 4 514 3 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

nuclear mRNA splicing, via spliceosome 5.7698E-8 4 99 4 6292
RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 6.0102E-8 4 100 4 6292
RNA splicing, via transesterification reactions 7.9099E-8 4 107 4 6292
RNA splicing 1.852E-7 4 132 4 6292
mRNA processing 3.6385E-7 4 156 4 6292
mRNA metabolic process 1.2778E-6 4 213 4 6292
RNA processing 1.3107E-5 4 380 4 6292
RNA metabolic process 5.2568E-4 4 954 4 6292
cis assembly of pre-catalytic spliceosome 1.2712E-3 4 2 1 6292
gene expression 1.7224E-3 4 1283 4 6292
nuclear mRNA cis splicing, via spliceosome 1.9063E-3 4 3 1 6292
nucleic acid metabolic process 2.5494E-3 4 1415 4 6292
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 3.8261E-3 4 1566 4 6292
cellular nitrogen compound metabolic process 6.2471E-3 4 1770 4 6292
nitrogen compound metabolic process 6.5492E-3 4 1791 4 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

first spliceosomal transesterification activity 4.5436E-6 4 6 2 6292
binding 1.7823E-3 4 1294 4 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle