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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Ypk2. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 8 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
CDC33
  • nucleus
  • eukaryotic translation initiation factor 4F complex
  • cytoplasm
  • ribosome
  • nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
  • translational initiation
  • translation initiation factor activity
  • PET112
  • mitochondrion
  • aerobic respiration
  • mitochondrion organization
  • translation
  • molecular_function
  • PRB1
  • fungal-type vacuole lumen
  • fungal-type vacuole
  • cellular response to starvation
  • sporulation resulting in formation of a cellular spore
  • vacuolar protein catabolic process
  • serine-type endopeptidase activity
  • SNF1
  • nucleus
  • cytoplasm
  • mitochondrion
  • fungal-type vacuole
  • nuclear envelope lumen
  • AMP-activated protein kinase complex
  • regulation of carbohydrate metabolic process
  • signal transduction
  • pseudohyphal growth
  • cell adhesion
  • invasive growth in response to glucose limitation
  • protein amino acid phosphorylation
  • replicative cell aging
  • biofilm formation
  • positive regulation of gluconeogenesis
  • cellular response to nitrogen starvation
  • AMP-activated protein kinase activity
  • TFP1
  • vacuolar proton-transporting V-type ATPase, V1 domain
  • fungal-type vacuole membrane
  • protein metabolic process
  • vacuolar acidification
  • intron homing
  • proton-transporting ATPase activity, rotational mechanism
  • endodeoxyribonuclease activity
  • YEL023C
  • cellular_component
  • biological_process
  • molecular_function
  • YGR016W
  • cellular_component
  • biological_process
  • molecular_function
  • YPK2
  • nucleus
  • cytoplasm
  • protein amino acid phosphorylation
  • protein kinase activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    fungal-type vacuole 7.9303E-4 8 158 3 6292
    lytic vacuole 7.9303E-4 8 158 3 6292
    storage vacuole 7.9303E-4 8 158 3 6292
    vacuole 1.788E-3 8 209 3 6292
    nuclear envelope lumen 5.0773E-3 8 4 1 6292
    eukaryotic translation initiation factor 4F complex 5.0773E-3 8 4 1 6292
    AMP-activated protein kinase complex 7.6075E-3 8 6 1 6292
    fungal-type vacuole lumen 8.8705E-3 8 7 1 6292
    vacuolar part 9.5206E-3 8 121 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cellular response to starvation 3.2267E-4 8 22 2 6292
    response to starvation 3.2267E-4 8 22 2 6292
    protein metabolic process 6.8696E-4 8 1136 6 6292
    cellular response to external stimulus 8.2428E-4 8 35 2 6292
    cellular response to extracellular stimulus 8.2428E-4 8 35 2 6292
    cellular response to nutrient levels 8.2428E-4 8 35 2 6292
    response to extracellular stimulus 9.7204E-4 8 38 2 6292
    response to nutrient levels 9.7204E-4 8 38 2 6292
    response to external stimulus 9.7204E-4 8 38 2 6292
    cell communication 1.6147E-3 8 49 2 6292
    cellular response to nitrogen levels 2.5415E-3 8 2 1 6292
    cellular response to nitrogen starvation 2.5415E-3 8 2 1 6292
    positive regulation of gluconeogenesis 5.0773E-3 8 4 1 6292
    cellular protein metabolic process 5.103E-3 8 1074 5 6292
    protein amino acid phosphorylation 6.9683E-3 8 103 2 6292
    biofilm formation 7.6075E-3 8 6 1 6292
    intron homing 7.6075E-3 8 6 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    serine-type endopeptidase activity 5.0773E-3 8 4 1 6292
    serine-type peptidase activity 7.6075E-3 8 6 1 6292
    AMP-activated protein kinase activity 7.6075E-3 8 6 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle