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View Protein Complex Details

Complex Overview

From Publication: Krogan N. J. et al. (2006) Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature. 2006 Mar 30;440(7084):637-43. Epub 2006 Mar 22.
Notes: From the published set of core protein complex predictions.
Complex Size: 13 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
CPR7
  • cytosol
  • response to stress
  • peptidyl-prolyl cis-trans isomerase activity
  • unfolded protein binding
  • GBP2
  • nucleus
  • telomere maintenance
  • poly(A)+ mRNA export from nucleus
  • RNA binding
  • telomeric DNA binding
  • GVP36
  • cytoplasm
  • integral to Golgi membrane
  • biological_process
  • molecular_function
  • HHO1
  • nucleus
  • nuclear nucleosome
  • regulation of transcription, DNA-dependent
  • negative regulation of DNA recombination
  • DNA binding
  • HPR1
  • Cdc73/Paf1 complex
  • THO complex
  • mRNA export from nucleus
  • DNA recombination
  • telomere maintenance
  • response to DNA damage stimulus
  • RNA elongation from RNA polymerase II promoter
  • nucleic acid binding
  • HRB1
  • nucleus
  • cytoplasm
  • heterogeneous nuclear ribonucleoprotein complex
  • poly(A)+ mRNA export from nucleus
  • RNA binding
  • MFT1
  • THO complex
  • mRNA export from nucleus
  • DNA recombination
  • telomere maintenance
  • RNA elongation from RNA polymerase II promoter
  • nucleic acid binding
  • SUB2
  • chromosome, telomeric region
  • nucleus
  • spliceosomal complex
  • transcription export complex
  • mRNA export from nucleus
  • chromatin silencing at telomere
  • nuclear mRNA splicing, via spliceosome
  • RNA binding
  • protein binding
  • ATP-dependent RNA helicase activity
  • TEX1
  • transcription export complex
  • mRNA export from nucleus
  • molecular_function
  • THO2
  • nucleus
  • THO complex
  • mRNA export from nucleus
  • DNA recombination
  • RNA elongation from RNA polymerase II promoter
  • nucleic acid binding
  • DNA binding
  • THP2
  • THO complex
  • mRNA export from nucleus
  • DNA recombination
  • telomere maintenance
  • RNA elongation from RNA polymerase II promoter
  • nucleic acid binding
  • ULS1
  • nucleus
  • mitochondrion
  • chromatin assembly or disassembly
  • mating type switching
  • DNA-dependent ATPase activity
  • YNL140C

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    THO complex 1.0959E-11 13 4 4 6292
    transcription export complex 2.3591E-5 13 4 2 6292
    nuclear part 4.865E-4 13 1103 8 6292
    nucleus 1.2848E-3 13 2041 10 6292
    heterogeneous nuclear ribonucleoprotein complex 6.1865E-3 13 3 1 6292
    macromolecular complex 7.225E-3 13 1635 8 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    mRNA transport 1.5031E-13 13 68 8 6292
    mRNA export from nucleus 1.5031E-13 13 68 8 6292
    RNA export from nucleus 5.8439E-13 13 80 8 6292
    RNA transport 6.4797E-13 13 81 8 6292
    nucleic acid transport 6.4797E-13 13 81 8 6292
    establishment of RNA localization 6.4797E-13 13 81 8 6292
    RNA localization 1.8605E-12 13 92 8 6292
    nucleobase, nucleoside, nucleotide and nucleic acid transport 2.6428E-12 13 96 8 6292
    nuclear export 4.7151E-12 13 103 8 6292
    nuclear transport 3.1591E-11 13 130 8 6292
    nucleocytoplasmic transport 3.1591E-11 13 130 8 6292
    macromolecule localization 2.2801E-7 13 397 8 6292
    RNA elongation from RNA polymerase II promoter 8.6592E-7 13 39 4 6292
    RNA elongation 1.5578E-6 13 45 4 6292
    DNA recombination 2.0499E-6 13 114 5 6292
    intracellular transport 2.9312E-6 13 553 8 6292
    establishment of localization in cell 5.3835E-6 13 599 8 6292
    cellular localization 9.2047E-6 13 643 8 6292
    DNA metabolic process 6.0397E-5 13 585 7 6292
    poly(A)+ mRNA export from nucleus 8.2282E-5 13 7 2 6292
    transport 2.3586E-4 13 997 8 6292
    establishment of localization 2.5529E-4 13 1008 8 6292
    transcription, DNA-dependent 2.672E-4 13 503 6 6292
    RNA biosynthetic process 2.8218E-4 13 508 6 6292
    localization 3.6634E-4 13 1060 8 6292
    transcription 4.4522E-4 13 552 6 6292
    anatomical structure homeostasis 2.1573E-3 13 286 4 6292
    telomere organization 2.1573E-3 13 286 4 6292
    telomere maintenance 2.1573E-3 13 286 4 6292
    nucleic acid metabolic process 2.7547E-3 13 1415 8 6292
    chromosome organization 3.7071E-3 13 555 5 6292
    transcription from RNA polymerase II promoter 3.8457E-3 13 335 4 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 5.439E-3 13 1566 8 6292
    homeostatic process 7.7877E-3 13 408 4 6292
    RNA metabolic process 7.8824E-3 13 954 6 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    nucleic acid binding 1.1996E-5 13 666 8 6292
    binding 2.0459E-4 13 1294 9 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle