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View Protein Complex Details

Complex Overview

From Publication: Krogan N. J. et al. (2006) Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature. 2006 Mar 30;440(7084):637-43. Epub 2006 Mar 22.
Notes: From the published set of core protein complex predictions.
Complex Size: 13 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

U2 snRNP 2.7212E-20 13 13 8 6292
small nuclear ribonucleoprotein complex 7.9031E-14 13 63 8 6292
ribonucleoprotein complex 2.7819E-9 13 514 10 6292
nucleus 4.29E-7 13 2041 13 6292
nuclear part 4.5247E-6 13 1103 10 6292
macromolecular complex 1.7639E-4 13 1635 10 6292
membrane-bounded organelle 1.2767E-3 13 3771 13 6292
intracellular membrane-bounded organelle 1.2767E-3 13 3771 13 6292
organelle part 3.3831E-3 13 2282 10 6292
intracellular organelle part 3.3831E-3 13 2282 10 6292
intracellular organelle 3.4477E-3 13 4070 13 6292
organelle 3.4587E-3 13 4071 13 6292
spliceosomal complex 3.7109E-3 13 45 2 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

RNA splicing 1.7144E-17 13 132 11 6292
nuclear mRNA splicing, via spliceosome 1.6107E-16 13 99 10 6292
RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 1.7888E-16 13 100 10 6292
RNA splicing, via transesterification reactions 3.6199E-16 13 107 10 6292
mRNA processing 1.7665E-14 13 156 10 6292
mRNA metabolic process 4.2014E-13 13 213 10 6292
RNA processing 2.3731E-12 13 380 11 6292
spliceosome assembly 3.3001E-8 13 18 4 6292
RNA metabolic process 5.3775E-8 13 954 11 6292
gene expression 1.2671E-6 13 1283 11 6292
nucleic acid metabolic process 3.5616E-6 13 1415 11 6292
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 1.0311E-5 13 1566 11 6292
ribonucleoprotein complex assembly 2.7675E-5 13 92 4 6292
cellular nitrogen compound metabolic process 3.6818E-5 13 1770 11 6292
nitrogen compound metabolic process 4.1589E-5 13 1791 11 6292
cellular macromolecular complex assembly 3.9465E-4 13 182 4 6292
cellular macromolecule metabolic process 4.9766E-4 13 2285 11 6292
macromolecule metabolic process 6.5617E-4 13 2349 11 6292
cellular macromolecular complex subunit organization 1.4943E-3 13 259 4 6292
macromolecular complex assembly 2.0214E-3 13 281 4 6292
macromolecular complex subunit organization 4.8383E-3 13 357 4 6292
primary metabolic process 5.1003E-3 13 2896 11 6292
ribonucleoprotein complex biogenesis 5.7164E-3 13 374 4 6292
cellular component assembly 6.3393E-3 13 385 4 6292
cellular metabolic process 7.9165E-3 13 3033 11 6292
cellular bud site selection 9.7882E-3 13 74 2 6292
cytokinesis, site selection 9.7882E-3 13 74 2 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

RNA binding 1.2363E-7 13 367 8 6292
nucleic acid binding 1.1996E-5 13 666 8 6292
binding 1.4925E-3 13 1294 8 6292
NAD(P)H dehydrogenase (quinone) activity 2.0661E-3 13 1 1 6292
U2 snRNA binding 2.0661E-3 13 1 1 6292
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor 4.1283E-3 13 2 1 6292

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