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View Protein Complex Details

Complex Overview

From Publication: Krogan N. J. et al. (2006) Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature. 2006 Mar 30;440(7084):637-43. Epub 2006 Mar 22.
Notes: From the published set of core protein complex predictions.
Complex Size: 16 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
ARC1
  • cytoplasm
  • methionyl glutamyl tRNA synthetase complex
  • tRNA aminoacylation for protein translation
  • tRNA export from nucleus
  • tRNA binding
  • ATG14
  • membrane fraction
  • autophagy
  • molecular_function
  • CAT8
  • nucleus
  • positive regulation of transcription from RNA polymerase II promoter
  • positive regulation of gluconeogenesis
  • specific RNA polymerase II transcription factor activity
  • CCC2
  • trans-Golgi network transport vesicle membrane
  • cellular iron ion homeostasis
  • intracellular copper ion transport
  • cation-transporting ATPase activity
  • HEK2
  • cytoplasm
  • nuclear chromosome, telomeric region
  • intracellular mRNA localization
  • telomere maintenance via telomerase
  • mRNA binding
  • IRC20
  • nucleus
  • mitochondrion
  • biological_process
  • molecular_function
  • MCA1
  • nucleus
  • apoptosis
  • caspase activity
  • MES1
  • cytoplasm
  • methionyl glutamyl tRNA synthetase complex
  • methionyl-tRNA aminoacylation
  • methionine-tRNA ligase activity
  • MGA2
  • endoplasmic reticulum membrane
  • response to cold
  • positive regulation of transcription from RNA polymerase II promoter
  • fatty acid metabolic process
  • transcription activator activity
  • NCS2
  • cytoplasm
  • protein modification process
  • pseudohyphal growth
  • ribosome biogenesis
  • invasive growth in response to glucose limitation
  • molecular_function
  • NHA1
  • plasma membrane
  • cellular potassium ion homeostasis
  • response to osmotic stress
  • cellular monovalent inorganic cation homeostasis
  • sodium:hydrogen antiporter activity
  • cation:cation antiporter activity
  • PET127
  • mitochondrion
  • mitochondrial envelope
  • RNA processing
  • molecular_function
  • PHO89
  • plasma membrane
  • phosphate transport
  • sodium:inorganic phosphate symporter activity
  • PHO91
  • membrane
  • phosphate transport
  • phosphate transmembrane transporter activity
  • YKL050C
  • cellular_component
  • biological_process
  • molecular_function
  • YLR363W-A
  • nucleus
  • biological_process
  • molecular_function
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    methionyl glutamyl tRNA synthetase complex 3.6271E-5 16 4 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    phosphate transport 3.2905E-4 16 11 2 6292
    inorganic anion transport 9.059E-4 16 18 2 6292
    anion transport 1.7579E-3 16 25 2 6292
    tRNA aminoacylation for protein translation 3.0575E-3 16 33 2 6292
    tRNA aminoacylation 3.0575E-3 16 33 2 6292
    amino acid activation 3.0575E-3 16 33 2 6292
    ion transport 3.1601E-3 16 120 3 6292
    carboxylic acid metabolic process 8.4451E-3 16 333 4 6292
    organic acid metabolic process 8.4451E-3 16 333 4 6292
    oxoacid metabolic process 8.4451E-3 16 333 4 6292
    cellular ketone metabolic process 9.6521E-3 16 346 4 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    phosphate transmembrane transporter activity 2.1602E-4 16 9 2 6292
    ion transmembrane transporter activity 4.0745E-4 16 146 4 6292
    inorganic anion transmembrane transporter activity 6.2447E-4 16 15 2 6292
    anion transmembrane transporter activity 1.2379E-3 16 21 2 6292
    secondary active transmembrane transporter activity 1.9016E-3 16 26 2 6292
    sodium:phosphate symporter activity 2.5429E-3 16 1 1 6292
    sodium:inorganic phosphate symporter activity 2.5429E-3 16 1 1 6292
    anion:cation symporter activity 2.5429E-3 16 1 1 6292
    sodium:hydrogen antiporter activity 2.5429E-3 16 1 1 6292
    cation transmembrane transporter activity 3.0128E-3 16 118 3 6292
    active transmembrane transporter activity 3.2354E-3 16 121 3 6292
    substrate-specific transmembrane transporter activity 3.8508E-3 16 267 4 6292
    methionine-tRNA ligase activity 5.0798E-3 16 2 1 6292
    caspase activity 5.0798E-3 16 2 1 6292
    solute:hydrogen antiporter activity 5.0798E-3 16 2 1 6292
    monovalent cation:hydrogen antiporter activity 5.0798E-3 16 2 1 6292
    transmembrane transporter activity 6.2704E-3 16 306 4 6292
    substrate-specific transporter activity 8.7141E-3 16 336 4 6292

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