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View Protein Complex Details

Complex Overview

From Publication: Krogan N. J. et al. (2006) Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature. 2006 Mar 30;440(7084):637-43. Epub 2006 Mar 22.
Notes: From the published set of core protein complex predictions.
Complex Size: 19 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
CTP1
  • mitochondrion
  • mitochondrial inner membrane
  • mitochondrial citrate transport
  • tricarboxylate secondary active transmembrane transporter activity
  • ERV25
  • ER to Golgi transport vesicle
  • ER to Golgi vesicle-mediated transport
  • molecular_function
  • FKS1
  • mitochondrion
  • 1,3-beta-glucan synthase complex
  • actin cortical patch
  • actin cap
  • 1,3-beta-glucan biosynthetic process
  • regulation of cell size
  • cellular cell wall organization
  • endocytosis
  • 1,3-beta-glucan synthase activity
  • FTR1
  • plasma membrane
  • high-affinity iron ion transport
  • iron ion transmembrane transporter activity
  • MRH1
  • mitochondrion
  • plasma membrane
  • biological_process
  • molecular_function
  • OLE1
  • endoplasmic reticulum membrane
  • mitochondrion inheritance
  • unsaturated fatty acid biosynthetic process
  • stearoyl-CoA 9-desaturase activity
  • PEX27
  • peroxisomal membrane
  • peroxisome organization
  • molecular_function
  • ROG3
  • cellular_component
  • biological_process
  • molecular_function
  • RPL10
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • RPL36B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL37A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPP1A
  • telomere maintenance
  • translational elongation
  • translation
  • structural constituent of ribosome
  • SEC11
  • endoplasmic reticulum
  • signal peptidase complex
  • signal peptide processing
  • protein targeting to ER
  • signal peptidase activity
  • SPC1
  • signal peptidase complex
  • signal peptide processing
  • protein targeting to ER
  • molecular_function
  • SPC2
  • signal peptidase complex
  • signal peptide processing
  • protein targeting to ER
  • protein binding
  • SPC3
  • signal peptidase complex
  • signal peptide processing
  • protein targeting to ER
  • signal peptidase activity
  • TCM62
  • mitochondrion
  • mitochondrial inner membrane
  • protein complex assembly
  • unfolded protein binding
  • TSC13
  • endoplasmic reticulum membrane
  • mitochondrion
  • very long-chain fatty acid metabolic process
  • oxidoreductase activity
  • YNR021W
  • endoplasmic reticulum
  • biological_process
  • molecular_function
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    signal peptidase complex 5.9409E-11 19 4 4 6292
    endoplasmic reticulum membrane 1.7248E-6 19 133 6 6292
    endoplasmic reticulum part 3.4881E-6 19 150 6 6292
    subsynaptic reticulum 3.4881E-6 19 150 6 6292
    membrane 2.8761E-5 19 1198 12 6292
    nuclear membrane-endoplasmic reticulum network 4.2684E-5 19 232 6 6292
    endoplasmic reticulum 5.6254E-5 19 364 7 6292
    organelle membrane 7.4509E-5 19 692 9 6292
    cytoplasmic part 8.1221E-5 19 2482 16 6292
    cytosolic large ribosomal subunit 7.1667E-4 19 60 3 6292
    endomembrane system 8.2523E-4 19 398 6 6292
    membrane part 2.2417E-3 19 662 7 6292
    cytosolic ribosome 3.2274E-3 19 101 3 6292
    large ribosomal subunit 4.1084E-3 19 110 3 6292
    intracellular organelle part 4.3784E-3 19 2282 13 6292
    organelle part 4.3784E-3 19 2282 13 6292
    cytosolic part 5.493E-3 19 122 3 6292
    1,3-beta-glucan synthase complex 9.0332E-3 19 3 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    protein maturation by peptide bond cleavage 2.0674E-9 19 7 4 6292
    signal peptide processing 2.0674E-9 19 7 4 6292
    peptide metabolic process 5.0731E-7 19 23 4 6292
    protein processing 2.025E-6 19 32 4 6292
    protein targeting to ER 2.2999E-6 19 33 4 6292
    protein localization in endoplasmic reticulum 5.0683E-6 19 40 4 6292
    protein maturation 5.0683E-6 19 40 4 6292
    protein localization in organelle 8.8722E-4 19 149 4 6292
    cellular localization 1.8901E-3 19 643 7 6292
    localization 1.9474E-3 19 1060 9 6292
    mitochondrial citrate transport 3.0197E-3 19 1 1 6292
    unsaturated fatty acid biosynthetic process 3.0197E-3 19 1 1 6292
    citrate transport 3.0197E-3 19 1 1 6292
    unsaturated fatty acid metabolic process 3.0197E-3 19 1 1 6292
    intracellular transport 4.4994E-3 19 553 6 6292
    protein targeting 4.7213E-3 19 235 4 6292
    transport 5.6941E-3 19 997 8 6292
    tricarboxylic acid transport 6.0308E-3 19 2 1 6292
    establishment of localization 6.099E-3 19 1008 8 6292
    intracellular protein transport 6.3103E-3 19 255 4 6292
    establishment of localization in cell 6.6803E-3 19 599 6 6292
    protein transport 7.6153E-3 19 269 4 6292
    establishment of protein localization 7.8153E-3 19 271 4 6292
    cellular protein localization 8.1219E-3 19 274 4 6292
    cellular protein metabolic process 9.0272E-3 19 1074 8 6292
    cellular macromolecule localization 9.2018E-3 19 284 4 6292
    fatty acid metabolic process 9.7086E-3 19 50 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    signal peptidase activity 8.6401E-6 19 2 2 6292
    stearoyl-CoA 9-desaturase activity 3.0197E-3 19 1 1 6292
    structural constituent of ribosome 3.2598E-3 19 212 4 6292
    tricarboxylate secondary active transmembrane transporter activity 6.0308E-3 19 2 1 6292
    1,3-beta-glucan synthase activity 9.0332E-3 19 3 1 6292
    oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 9.0332E-3 19 3 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle