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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 11 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

U1 snRNP 8.0318E-27 11 17 10 6292
small nuclear ribonucleoprotein complex 4.0524E-23 11 63 11 6292
ribonucleoprotein complex 9.7932E-13 11 514 11 6292
U4/U6 x U5 tri-snRNP complex 4.7839E-12 11 32 6 6292
U5 snRNP 1.1192E-11 11 14 5 6292
U2-type spliceosomal complex 2.486E-9 11 12 4 6292
commitment complex 2.486E-9 11 12 4 6292
nuclear part 4.6103E-9 11 1103 11 6292
macromolecular complex 3.5578E-7 11 1635 11 6292
spliceosomal complex 7.2654E-7 11 45 4 6292
nucleus 4.1084E-6 11 2041 11 6292
organelle part 1.4064E-5 11 2282 11 6292
intracellular organelle part 1.4064E-5 11 2282 11 6292
membrane-bounded organelle 3.5629E-3 11 3771 11 6292
intracellular membrane-bounded organelle 3.5629E-3 11 3771 11 6292
intracellular organelle 8.2563E-3 11 4070 11 6292
organelle 8.2787E-3 11 4071 11 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

nuclear mRNA splicing, via spliceosome 8.2951E-21 11 99 11 6292
RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 9.3204E-21 11 100 11 6292
RNA splicing, via transesterification reactions 2.039E-20 11 107 11 6292
RNA splicing 2.2776E-19 11 132 11 6292
mRNA processing 1.5305E-18 11 156 11 6292
mRNA metabolic process 5.1912E-17 11 213 11 6292
RNA processing 3.3986E-14 11 380 11 6292
RNA metabolic process 9.2688E-10 11 954 11 6292
gene expression 2.4488E-8 11 1283 11 6292
nucleic acid metabolic process 7.2197E-8 11 1415 11 6292
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 2.2108E-7 11 1566 11 6292
cellular nitrogen compound metabolic process 8.537E-7 11 1770 11 6292
nitrogen compound metabolic process 9.7232E-7 11 1791 11 6292
cellular macromolecule metabolic process 1.4269E-5 11 2285 11 6292
macromolecule metabolic process 1.9349E-5 11 2349 11 6292
primary metabolic process 1.9438E-4 11 2896 11 6292
cellular metabolic process 3.2347E-4 11 3033 11 6292
metabolic process 5.03E-4 11 3157 11 6292
nuclear mRNA 5'-splice site recognition 1.7483E-3 11 1 1 6292
nuclear mRNA cis splicing, via spliceosome 5.2364E-3 11 3 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

RNA binding 4.2317E-12 11 367 10 6292
nucleic acid binding 1.6541E-9 11 666 10 6292
mRNA binding 2.5762E-7 11 35 4 6292
binding 1.1791E-6 11 1294 10 6292
pre-mRNA 5'-splice site binding 1.7483E-3 11 1 1 6292
U1 snRNA binding 1.7483E-3 11 1 1 6292
snRNA binding 8.7135E-3 11 5 1 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle