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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 12 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
ARP7
  • nucleus
  • SWI/SNF complex
  • RSC complex
  • ATP-dependent chromatin remodeling
  • DNA-dependent ATPase activity
  • general RNA polymerase II transcription factor activity
  • ARP9
  • nucleus
  • SWI/SNF complex
  • RSC complex
  • ATP-dependent chromatin remodeling
  • DNA-dependent ATPase activity
  • general RNA polymerase II transcription factor activity
  • HTL1
  • RSC complex
  • chromatin remodeling
  • telomere maintenance
  • response to DNA damage stimulus
  • chromatin binding
  • NFI1
  • nucleus
  • nuclear chromatin
  • cytoplasm
  • protein sumoylation
  • chromosome condensation
  • telomere maintenance
  • chromosome segregation
  • SUMO ligase activity
  • NPL6
  • nucleus
  • RSC complex
  • chromatin remodeling
  • protein import into nucleus
  • ATP-dependent chromatin remodeling
  • telomere maintenance
  • response to DNA damage stimulus
  • DNA-dependent ATPase activity
  • RSC58
  • RSC complex
  • chromatin remodeling
  • molecular_function
  • RSC6
  • RSC complex
  • ATP-dependent chromatin remodeling
  • DNA-dependent ATPase activity
  • RSC8
  • nucleus
  • RSC complex
  • ATP-dependent chromatin remodeling
  • double-strand break repair via nonhomologous end joining
  • DNA-dependent ATPase activity
  • RSC9
  • RSC complex
  • chromatin remodeling
  • ATP-dependent chromatin remodeling
  • rRNA transcription
  • regulation of transcription from RNA polymerase II promoter
  • DNA-dependent ATPase activity
  • chromatin binding
  • RTT102
  • nucleus
  • SWI/SNF complex
  • RSC complex
  • chromatin remodeling
  • chromosome segregation
  • molecular_function
  • SFH1
  • RSC complex
  • G2/M transition of mitotic cell cycle
  • ATP-dependent chromatin remodeling
  • chromosome segregation
  • chromatin remodeling at centromere
  • double-strand break repair
  • DNA-dependent ATPase activity
  • STH1
  • RSC complex
  • cytoskeleton organization
  • ATP-dependent chromatin remodeling
  • chromosome segregation
  • chromatin remodeling at centromere
  • meiosis
  • double-strand break repair
  • ATPase activity
  • DNA-dependent ATPase activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    RSC complex 1.3246E-28 12 20 11 6292
    chromatin remodeling complex 9.8263E-20 12 99 11 6292
    nuclear part 8.0153E-10 12 1103 12 6292
    protein complex 6.4659E-8 12 1137 11 6292
    nucleus 1.3278E-6 12 2041 12 6292
    SWI/SNF-type complex 1.5001E-6 12 13 3 6292
    SWI/SNF complex 1.5001E-6 12 13 3 6292
    macromolecular complex 3.2574E-6 12 1635 11 6292
    organelle part 5.0851E-6 12 2282 12 6292
    intracellular organelle part 5.0851E-6 12 2282 12 6292
    membrane-bounded organelle 2.1329E-3 12 3771 12 6292
    intracellular membrane-bounded organelle 2.1329E-3 12 3771 12 6292
    intracellular organelle 5.3355E-3 12 4070 12 6292
    organelle 5.3513E-3 12 4071 12 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    chromatin remodeling 1.2006E-21 12 68 11 6292
    ATP-dependent chromatin remodeling 1.2621E-17 12 26 8 6292
    chromatin modification 4.163E-17 12 168 11 6292
    chromatin organization 3.521E-16 12 203 11 6292
    chromosome organization 1.9889E-13 12 555 12 6292
    organelle organization 1.0391E-9 12 1127 12 6292
    cellular component organization 6.186E-8 12 1582 12 6292
    chromatin remodeling at centromere 3.3348E-6 12 2 2 6292
    response to DNA damage stimulus 4.5415E-5 12 236 5 6292
    chromosome segregation 7.1288E-5 12 128 4 6292
    cellular response to stress 1.2181E-4 12 290 5 6292
    double-strand break repair 1.4638E-4 12 57 3 6292
    DNA metabolic process 3.5676E-4 12 585 6 6292
    cellular response to stimulus 4.2979E-4 12 379 5 6292
    response to stress 1.4952E-3 12 497 5 6292
    DNA repair 5.0207E-3 12 192 3 6292
    rRNA transcription 5.7116E-3 12 3 1 6292
    nucleic acid metabolic process 7.7238E-3 12 1415 7 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    DNA-dependent ATPase activity 9.6751E-15 12 55 8 6292
    ATPase activity, coupled 3.7472E-11 12 149 8 6292
    ATPase activity 6.1882E-10 12 211 8 6292
    nucleoside-triphosphatase activity 2.1178E-8 12 329 8 6292
    hydrolase activity, acting on acid anhydrides 3.6888E-8 12 353 8 6292
    hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 3.6888E-8 12 353 8 6292
    pyrophosphatase activity 3.6888E-8 12 353 8 6292
    hydrolase activity 5.3982E-5 12 911 8 6292
    chromatin binding 1.7038E-3 12 33 2 6292
    catalytic activity 4.6325E-3 12 2150 9 6292
    general RNA polymerase II transcription factor activity 6.2953E-3 12 64 2 6292
    SUMO ligase activity 9.5026E-3 12 5 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle