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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 13 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
ARX1
  • cytoplasm
  • nucleoplasm
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • molecular_function
  • IPI3
  • nucleus
  • nuclear outer membrane
  • nucleoplasm
  • ribosome biogenesis
  • ribosomal large subunit assembly
  • molecular_function
  • MRT4
  • nucleus
  • nucleolus
  • ribosomal large subunit biogenesis
  • telomere maintenance
  • ribosome biogenesis
  • rRNA processing
  • mRNA catabolic process
  • molecular_function
  • NOG1
  • nuclear outer membrane
  • nucleolus
  • preribosome, large subunit precursor
  • ribosomal subunit export from nucleus
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • GTP binding
  • NOG2
  • nucleus
  • nucleolus
  • nucleoplasm
  • ribosomal large subunit export from nucleus
  • ribosome biogenesis
  • ribosome assembly
  • GTPase activity
  • NOP7
  • nucleus
  • nucleolus
  • cell proliferation
  • maturation of SSU-rRNA
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • cell cycle
  • molecular_function
  • NSA2
  • nucleus
  • preribosome, large subunit precursor
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • processing of 27S pre-rRNA
  • molecular_function
  • NUG1
  • nucleus
  • nucleolus
  • ribosome biogenesis
  • rRNA processing
  • GTPase activity
  • RIX1
  • nucleus
  • nuclear outer membrane
  • nucleoplasm
  • ribosomal subunit export from nucleus
  • ribosome biogenesis
  • ribosomal large subunit assembly
  • molecular_function
  • RLP7
  • nucleolus
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • processing of 27S pre-rRNA
  • rRNA binding
  • RSA4
  • nucleolus
  • ribosome
  • ribosome biogenesis
  • ribosomal large subunit assembly
  • molecular_function
  • SDA1
  • nucleus
  • ribosome biogenesis
  • traversing start control point of mitotic cell cycle
  • ribosome assembly
  • actin cytoskeleton organization
  • molecular_function
  • TIF6
  • nucleus
  • cytoplasm
  • nuclear outer membrane
  • nucleolus
  • ribosomal subunit export from nucleus
  • ribosomal large subunit biogenesis
  • processing of 27S pre-rRNA
  • ribosomal large subunit binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    nuclear lumen 1.6415E-11 13 453 11 6292
    organelle lumen 1.0033E-9 13 660 11 6292
    intracellular organelle lumen 1.0033E-9 13 660 11 6292
    nucleolus 1.5628E-9 13 211 8 6292
    membrane-enclosed lumen 1.901E-9 13 700 11 6292
    nuclear part 2.5417E-7 13 1103 11 6292
    nucleus 4.29E-7 13 2041 13 6292
    nuclear outer membrane 2.1179E-5 13 86 4 6292
    nuclear membrane 3.412E-5 13 97 4 6292
    preribosome, large subunit precursor 1.4073E-4 13 9 2 6292
    non-membrane-bounded organelle 1.7806E-4 13 959 8 6292
    intracellular non-membrane-bounded organelle 1.7806E-4 13 959 8 6292
    outer membrane 3.6249E-4 13 178 4 6292
    organelle outer membrane 3.6249E-4 13 178 4 6292
    organelle part 4.9114E-4 13 2282 11 6292
    intracellular organelle part 4.9114E-4 13 2282 11 6292
    nuclear envelope 5.5461E-4 13 199 4 6292
    nuclear membrane-endoplasmic reticulum network 9.9015E-4 13 232 4 6292
    membrane-bounded organelle 1.2767E-3 13 3771 13 6292
    intracellular membrane-bounded organelle 1.2767E-3 13 3771 13 6292
    nucleoplasm 1.6043E-3 13 264 4 6292
    preribosome 2.13E-3 13 34 2 6292
    intracellular organelle 3.4477E-3 13 4070 13 6292
    organelle 3.4587E-3 13 4071 13 6292
    endomembrane system 7.1331E-3 13 398 4 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    ribosomal large subunit biogenesis 1.8786E-18 13 65 10 6292
    ribosome biogenesis 3.3886E-17 13 346 13 6292
    ribonucleoprotein complex biogenesis 9.4812E-17 13 374 13 6292
    cellular component biogenesis 3.2337E-13 13 694 13 6292
    ribosome assembly 1.1232E-7 13 64 5 6292
    establishment of ribosome localization 1.5976E-7 13 26 4 6292
    ribosome localization 1.5976E-7 13 26 4 6292
    ribosomal subunit export from nucleus 1.5976E-7 13 26 4 6292
    organelle assembly 1.6468E-7 13 69 5 6292
    ribonucleoprotein complex assembly 7.0307E-7 13 92 5 6292
    establishment of organelle localization 3.5251E-6 13 55 4 6292
    processing of 27S pre-rRNA 3.8002E-6 13 16 3 6292
    organelle localization 2.0217E-5 13 85 4 6292
    cellular macromolecular complex assembly 2.0432E-5 13 182 5 6292
    nuclear export 4.3238E-5 13 103 4 6292
    ribosomal large subunit assembly 7.0211E-5 13 41 3 6292
    nuclear transport 1.0767E-4 13 130 4 6292
    nucleocytoplasmic transport 1.0767E-4 13 130 4 6292
    cellular macromolecular complex subunit organization 1.1152E-4 13 259 5 6292
    macromolecular complex assembly 1.6416E-4 13 281 5 6292
    ribosomal subunit assembly 1.6993E-4 13 55 3 6292
    obsolete_biological_process 2.2032E-4 13 60 3 6292
    macromolecular complex subunit organization 5.0375E-4 13 357 5 6292
    cellular component assembly 7.1393E-4 13 385 5 6292
    rRNA processing 2.0259E-3 13 128 3 6292
    rRNA metabolic process 2.4612E-3 13 137 3 6292
    ncRNA processing 8.7308E-3 13 215 3 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    ribosomal large subunit binding 2.0661E-3 13 1 1 6292
    GTPase activity 6.7329E-3 13 61 2 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle