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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 13 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
DST1
  • nucleoplasm
    		•
  • reciprocal meiotic recombination
  • RNA elongation from RNA polymerase II promoter
  • mRNA cleavage
    		•
  • positive transcription elongation factor activity
    		•
    RPB10
  • DNA-directed RNA polymerase I complex
  • DNA-directed RNA polymerase III complex
  • DNA-directed RNA polymerase II, core complex
    		•
  • transcription from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • transcription from RNA polymerase II promoter
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPB11
  • DNA-directed RNA polymerase II, core complex
    		•
  • transcription from RNA polymerase II promoter
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPB3
  • DNA-directed RNA polymerase II, core complex
    		•
  • transcription from RNA polymerase II promoter
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPB5
  • DNA-directed RNA polymerase I complex
  • DNA-directed RNA polymerase III complex
  • DNA-directed RNA polymerase II, core complex
    		•
  • transcription from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • transcription from RNA polymerase II promoter
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPB7
  • DNA-directed RNA polymerase II, core complex
    		•
  • transcription from RNA polymerase II promoter
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPB8
  • DNA-directed RNA polymerase I complex
  • DNA-directed RNA polymerase III complex
  • DNA-directed RNA polymerase II, core complex
    		•
  • transcription from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • transcription from RNA polymerase II promoter
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPB9
  • DNA-directed RNA polymerase II, core complex
    		•
  • response to drug
  • transcription-coupled nucleotide-excision repair
  • telomere maintenance
  • transcription from RNA polymerase II promoter
  • response to DNA damage stimulus
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPC10
  • DNA-directed RNA polymerase I complex
  • DNA-directed RNA polymerase III complex
  • DNA-directed RNA polymerase II, core complex
    		•
  • transcription from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • transcription from RNA polymerase II promoter
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPO21
  • mitochondrion
  • DNA-directed RNA polymerase II, core complex
    		•
  • transcription from RNA polymerase II promoter
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPO26
  • DNA-directed RNA polymerase I complex
  • DNA-directed RNA polymerase III complex
  • DNA-directed RNA polymerase II, core complex
    		•
  • transcription from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • transcription from RNA polymerase II promoter
    		•
  • DNA-directed RNA polymerase activity
    		•
    TFG1
  • transcription factor TFIIF complex
    		•
  • transcription initiation from RNA polymerase II promoter
    		•
  • general RNA polymerase II transcription factor activity
    		•
    TFG2
  • transcription factor TFIIF complex
    		•
  • transcription initiation from RNA polymerase II promoter
    		•
  • general RNA polymerase II transcription factor activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    DNA-directed RNA polymerase II, core complex 7.0879E-28 13 12 10 6292
    DNA-directed RNA polymerase II, holoenzyme 9.0675E-25 13 56 12 6292
    RNA polymerase complex 4.7239E-22 13 31 10 6292
    nuclear DNA-directed RNA polymerase complex 4.7239E-22 13 31 10 6292
    DNA-directed RNA polymerase complex 4.7239E-22 13 31 10 6292
    nucleoplasm 9.3669E-19 13 264 13 6292
    nucleoplasm part 1.1723E-16 13 245 12 6292
    nuclear lumen 1.1883E-15 13 453 13 6292
    organelle lumen 1.6732E-13 13 660 13 6292
    intracellular organelle lumen 1.6732E-13 13 660 13 6292
    membrane-enclosed lumen 3.6201E-13 13 700 13 6292
    DNA-directed RNA polymerase I complex 3.1104E-11 13 14 5 6292
    DNA-directed RNA polymerase III complex 9.5835E-11 13 17 5 6292
    nuclear part 1.3925E-10 13 1103 13 6292
    protein complex 1.2542E-8 13 1137 12 6292
    nucleolar part 1.8366E-8 13 45 5 6292
    nucleus 4.29E-7 13 2041 13 6292
    macromolecular complex 9.1057E-7 13 1635 12 6292
    organelle part 1.8381E-6 13 2282 13 6292
    intracellular organelle part 1.8381E-6 13 2282 13 6292
    transcription factor TFIIF complex 1.1809E-5 13 3 2 6292
    nucleolus 4.1788E-5 13 211 5 6292
    membrane-bounded organelle 1.2767E-3 13 3771 13 6292
    intracellular membrane-bounded organelle 1.2767E-3 13 3771 13 6292
    intracellular organelle 3.4477E-3 13 4070 13 6292
    organelle 3.4587E-3 13 4071 13 6292
    transcription factor complex 9.0369E-3 13 71 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    transcription from RNA polymerase II promoter 2.2096E-17 13 335 13 6292
    transcription, DNA-dependent 4.7164E-15 13 503 13 6292
    RNA biosynthetic process 5.3719E-15 13 508 13 6292
    transcription 1.6014E-14 13 552 13 6292
    RNA metabolic process 2.0874E-11 13 954 13 6292
    cellular macromolecule biosynthetic process 3.6337E-10 13 1187 13 6292
    macromolecule biosynthetic process 3.7146E-10 13 1189 13 6292
    gene expression 1.0037E-9 13 1283 13 6292
    transcription from RNA polymerase I promoter 2.1767E-9 13 30 5 6292
    nucleic acid metabolic process 3.6054E-9 13 1415 13 6292
    transcription from RNA polymerase III promoter 7.602E-9 13 38 5 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 1.3544E-8 13 1566 13 6292
    cellular biosynthetic process 1.3657E-8 13 1567 13 6292
    biosynthetic process 1.822E-8 13 1602 13 6292
    cellular nitrogen compound metabolic process 6.6927E-8 13 1770 13 6292
    nitrogen compound metabolic process 7.8058E-8 13 1791 13 6292
    cellular macromolecule metabolic process 1.8698E-6 13 2285 13 6292
    macromolecule metabolic process 2.6802E-6 13 2349 13 6292
    primary metabolic process 4.1002E-5 13 2896 13 6292
    cellular metabolic process 7.4867E-5 13 3033 13 6292
    metabolic process 1.2617E-4 13 3157 13 6292
    transcription initiation from RNA polymerase II promoter 4.0426E-3 13 47 2 6292
    transcription-coupled nucleotide-excision repair 4.1283E-3 13 2 1 6292
    transcription initiation 6.103E-3 13 58 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    RNA polymerase activity 1.3948E-21 13 34 10 6292
    DNA-directed RNA polymerase activity 1.3948E-21 13 34 10 6292
    nucleotidyltransferase activity 3.7667E-14 13 168 10 6292
    transferase activity, transferring phosphorus-containing groups 3.7804E-10 13 420 10 6292
    transferase activity 2.0145E-7 13 797 10 6292
    catalytic activity 2.0237E-3 13 2150 10 6292
    positive transcription elongation factor activity 2.0661E-3 13 1 1 6292
    general RNA polymerase II transcription factor activity 7.3913E-3 13 64 2 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle