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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 18 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
RPL11B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • RPL12B, RPL12A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • regulation of translation
  • translational termination
  • ribosomal large subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL16A
  • ribonucleoprotein complex
  • cytoplasm
  • large ribosomal subunit
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL18A, RPL18B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • regulation of translation
  • translation
  • structural constituent of ribosome
  • RPL20A
  • translation
  • structural constituent of ribosome
  • RPL2A, RPL2B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • regulation of translation
  • response to drug
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPL3
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • RPL36A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL4A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPL5
  • ribosomal large subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPS16B, RPS16A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosomal small subunit biogenesis
  • translation
  • structural constituent of ribosome
  • RPS17B
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • intracellular
  • telomere maintenance
  • ribosomal small subunit assembly
  • translation
  • structural constituent of ribosome
  • RPS2
  • small nucleolar ribonucleoprotein complex
  • regulation of translational fidelity
  • translation
  • structural constituent of ribosome
  • RPS3
  • preribosome, small subunit precursor
  • response to DNA damage stimulus
  • translation
  • structural constituent of ribosome
  • RPS30B, RPS30A
  • stress granule
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS5
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • small ribosomal subunit
  • 90S preribosome
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS8B, RPS8A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • 90S preribosome
  • ribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • translation
  • structural constituent of ribosome
  • RPS9B
  • small nucleolar ribonucleoprotein complex
  • regulation of translational fidelity
  • translation
  • structural constituent of ribosome
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cytosolic ribosome 1.7045E-20 18 101 13 6292
    cytosolic part 2.2581E-19 18 122 13 6292
    ribosomal subunit 5.2615E-17 18 183 13 6292
    ribonucleoprotein complex 4.1489E-16 18 514 16 6292
    cytosol 1.7269E-14 18 284 13 6292
    ribosome 2.2691E-14 18 290 13 6292
    cytosolic large ribosomal subunit 1.7145E-12 18 60 8 6292
    large ribosomal subunit 2.556E-10 18 110 8 6292
    macromolecular complex 3.5912E-8 18 1635 16 6292
    cytosolic small ribosomal subunit 4.9512E-8 18 38 5 6292
    non-membrane-bounded organelle 9.0245E-8 18 959 13 6292
    intracellular non-membrane-bounded organelle 9.0245E-8 18 959 13 6292
    small ribosomal subunit 1.3945E-6 18 73 5 6292
    preribosome 2.0618E-6 18 34 4 6292
    90S preribosome 1.3041E-5 18 17 3 6292
    organelle part 2.0665E-3 18 2282 13 6292
    intracellular organelle part 2.0665E-3 18 2282 13 6292
    stress granule 2.8608E-3 18 1 1 6292
    cytoplasmic part 4.9394E-3 18 2482 13 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 6.4007E-23 18 376 18 6292
    cellular protein metabolic process 1.3435E-14 18 1074 18 6292
    protein metabolic process 3.7187E-14 18 1136 18 6292
    cellular macromolecule biosynthetic process 8.2458E-14 18 1187 18 6292
    macromolecule biosynthetic process 8.5013E-14 18 1189 18 6292
    gene expression 3.3762E-13 18 1283 18 6292
    cellular biosynthetic process 1.262E-11 18 1567 18 6292
    biosynthetic process 1.8822E-11 18 1602 18 6292
    regulation of translation 1.0092E-10 18 57 7 6292
    posttranscriptional regulation of gene expression 1.6551E-10 18 61 7 6292
    regulation of cellular protein metabolic process 3.6382E-10 18 68 7 6292
    regulation of protein metabolic process 6.6914E-10 18 74 7 6292
    cellular macromolecule metabolic process 1.1566E-8 18 2285 18 6292
    macromolecule metabolic process 1.9051E-8 18 2349 18 6292
    ribosomal subunit assembly 3.332E-7 18 55 5 6292
    ribosome assembly 7.1898E-7 18 64 5 6292
    primary metabolic process 8.3514E-7 18 2896 18 6292
    organelle assembly 1.0506E-6 18 69 5 6292
    cellular metabolic process 1.9237E-6 18 3033 18 6292
    metabolic process 3.9649E-6 18 3157 18 6292
    ribonucleoprotein complex assembly 4.4174E-6 18 92 5 6292
    ribosomal large subunit assembly 4.4463E-6 18 41 4 6292
    ribosome biogenesis 2.6886E-5 18 346 7 6292
    ribosomal large subunit biogenesis 2.8477E-5 18 65 4 6292
    ribonucleoprotein complex biogenesis 4.4531E-5 18 374 7 6292
    cellular macromolecular complex assembly 1.2088E-4 18 182 5 6292
    regulation of gene expression 1.3536E-4 18 445 7 6292
    regulation of macromolecule biosynthetic process 1.5794E-4 18 456 7 6292
    regulation of cellular biosynthetic process 1.9624E-4 18 472 7 6292
    regulation of biosynthetic process 1.9887E-4 18 473 7 6292
    regulation of macromolecule metabolic process 2.4183E-4 18 488 7 6292
    regulation of translational fidelity 2.7502E-4 18 9 2 6292
    regulation of primary metabolic process 3.3415E-4 18 514 7 6292
    regulation of cellular metabolic process 4.3304E-4 18 536 7 6292
    regulation of metabolic process 4.9072E-4 18 547 7 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 5.9184E-4 18 13 2 6292
    regulation of translational elongation 5.9184E-4 18 13 2 6292
    cellular macromolecular complex subunit organization 6.2655E-4 18 259 5 6292
    macromolecular complex assembly 9.088E-4 18 281 5 6292
    cellular process 1.7601E-3 18 4426 18 6292
    cellular component biogenesis 2.0553E-3 18 694 7 6292
    ribosomal small subunit biogenesis 2.4123E-3 18 26 2 6292
    macromolecular complex subunit organization 2.6496E-3 18 357 5 6292
    translational elongation 2.9982E-3 18 29 2 6292
    cellular component assembly 3.6848E-3 18 385 5 6292
    regulation of cellular process 4.5442E-3 18 796 7 6292
    regulation of biological process 5.5269E-3 18 824 7 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 1.5275E-27 18 212 18 6292
    structural molecule activity 9.4732E-24 18 339 18 6292
    RNA binding 2.9908E-3 18 367 5 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle