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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 18 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
RPL10
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • RPL11B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • RPL12B, RPL12A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • regulation of translation
  • translational termination
  • ribosomal large subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL18A, RPL18B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • regulation of translation
  • translation
  • structural constituent of ribosome
  • RPL20A
  • translation
  • structural constituent of ribosome
  • RPL2A, RPL2B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • regulation of translation
  • response to drug
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPL3
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • RPL36A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL4A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPL5
  • ribosomal large subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPS16B, RPS16A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosomal small subunit biogenesis
  • translation
  • structural constituent of ribosome
  • RPS17B
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • intracellular
  • telomere maintenance
  • ribosomal small subunit assembly
  • translation
  • structural constituent of ribosome
  • RPS1A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • 90S preribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS2
  • small nucleolar ribonucleoprotein complex
  • regulation of translational fidelity
  • translation
  • structural constituent of ribosome
  • RPS3
  • preribosome, small subunit precursor
  • response to DNA damage stimulus
  • translation
  • structural constituent of ribosome
  • RPS30B, RPS30A
  • stress granule
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS5
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • small ribosomal subunit
  • 90S preribosome
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS8B, RPS8A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • 90S preribosome
  • ribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • translation
  • structural constituent of ribosome
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cytosolic ribosome 8.6467E-23 18 101 14 6292
    cytosolic part 1.4233E-21 18 122 14 6292
    ribosomal subunit 5.2191E-19 18 183 14 6292
    cytosol 2.7723E-16 18 284 14 6292
    ribosome 3.7266E-16 18 290 14 6292
    ribonucleoprotein complex 4.1489E-16 18 514 16 6292
    cytosolic large ribosomal subunit 1.7145E-12 18 60 8 6292
    large ribosomal subunit 2.556E-10 18 110 8 6292
    cytosolic small ribosomal subunit 5.6562E-10 18 38 6 6292
    non-membrane-bounded organelle 5.627E-9 18 959 14 6292
    intracellular non-membrane-bounded organelle 5.627E-9 18 959 14 6292
    preribosome 2.7638E-8 18 34 5 6292
    small ribosomal subunit 3.2925E-8 18 73 6 6292
    macromolecular complex 3.5912E-8 18 1635 16 6292
    90S preribosome 1.0907E-7 18 17 4 6292
    organelle part 3.9495E-4 18 2282 14 6292
    intracellular organelle part 3.9495E-4 18 2282 14 6292
    cytoplasmic part 1.0714E-3 18 2482 14 6292
    stress granule 2.8608E-3 18 1 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 6.4007E-23 18 376 18 6292
    cellular protein metabolic process 1.3435E-14 18 1074 18 6292
    protein metabolic process 3.7187E-14 18 1136 18 6292
    cellular macromolecule biosynthetic process 8.2458E-14 18 1187 18 6292
    macromolecule biosynthetic process 8.5013E-14 18 1189 18 6292
    gene expression 3.3762E-13 18 1283 18 6292
    cellular biosynthetic process 1.262E-11 18 1567 18 6292
    biosynthetic process 1.8822E-11 18 1602 18 6292
    ribosomal subunit assembly 5.7758E-9 18 55 6 6292
    regulation of translation 7.2062E-9 18 57 6 6292
    posttranscriptional regulation of gene expression 1.0954E-8 18 61 6 6292
    cellular macromolecule metabolic process 1.1566E-8 18 2285 18 6292
    ribosome assembly 1.4718E-8 18 64 6 6292
    macromolecule metabolic process 1.9051E-8 18 2349 18 6292
    regulation of cellular protein metabolic process 2.1345E-8 18 68 6 6292
    organelle assembly 2.334E-8 18 69 6 6292
    regulation of protein metabolic process 3.5771E-8 18 74 6 6292
    ribosomal large subunit assembly 7.3539E-8 18 41 5 6292
    ribonucleoprotein complex assembly 1.3366E-7 18 92 6 6292
    ribosomal large subunit biogenesis 7.7755E-7 18 65 5 6292
    primary metabolic process 8.3514E-7 18 2896 18 6292
    cellular metabolic process 1.9237E-6 18 3033 18 6292
    ribosome biogenesis 2.0778E-6 18 346 8 6292
    ribonucleoprotein complex biogenesis 3.738E-6 18 374 8 6292
    metabolic process 3.9649E-6 18 3157 18 6292
    cellular macromolecular complex assembly 7.4975E-6 18 182 6 6292
    cellular macromolecular complex subunit organization 5.612E-5 18 259 6 6292
    macromolecular complex assembly 8.8608E-5 18 281 6 6292
    macromolecular complex subunit organization 3.3144E-4 18 357 6 6292
    cellular component biogenesis 3.3522E-4 18 694 8 6292
    cellular component assembly 4.9868E-4 18 385 6 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 5.9184E-4 18 13 2 6292
    regulation of gene expression 1.079E-3 18 445 6 6292
    regulation of macromolecule biosynthetic process 1.2269E-3 18 456 6 6292
    regulation of cellular biosynthetic process 1.4697E-3 18 472 6 6292
    regulation of biosynthetic process 1.486E-3 18 473 6 6292
    regulation of macromolecule metabolic process 1.7483E-3 18 488 6 6292
    cellular process 1.7601E-3 18 4426 18 6292
    regulation of primary metabolic process 2.2861E-3 18 514 6 6292
    ribosomal small subunit biogenesis 2.4123E-3 18 26 2 6292
    regulation of cellular metabolic process 2.8336E-3 18 536 6 6292
    regulation of metabolic process 3.1423E-3 18 547 6 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 1.5275E-27 18 212 18 6292
    structural molecule activity 9.4732E-24 18 339 18 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle