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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 9 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
RPL15A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL16A
  • ribonucleoprotein complex
  • cytoplasm
  • large ribosomal subunit
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL17A
  • cytoplasm
  • translation
  • structural constituent of ribosome
  • RPL17B
  • ribonucleoprotein complex
  • cytoplasm
  • large ribosomal subunit
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPL2A, RPL2B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • regulation of translation
  • response to drug
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPL6A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPS11A, RPS11B
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosomal small subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS14A
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • telomere maintenance
  • ribosomal small subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPS18B, RPS18A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • mitochondrion
  • ribosome
  • intracellular
  • rRNA export from nucleus
  • endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • translation
  • nucleic acid binding
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cytosolic ribosome 7.8116E-12 9 101 7 6292
    cytosolic part 3.0242E-11 9 122 7 6292
    ribosomal subunit 5.3877E-10 9 183 7 6292
    cytosolic large ribosomal subunit 8.1452E-9 9 60 5 6292
    cytosol 1.1829E-8 9 284 7 6292
    ribosome 1.3691E-8 9 290 7 6292
    ribonucleoprotein complex 1.576E-8 9 514 8 6292
    large ribosomal subunit 1.7771E-7 9 110 5 6292
    non-membrane-bounded organelle 5.0826E-5 9 959 7 6292
    intracellular non-membrane-bounded organelle 5.0826E-5 9 959 7 6292
    macromolecular complex 1.4222E-4 9 1635 8 6292
    cytosolic small ribosomal subunit 1.245E-3 9 38 2 6292
    small ribosomal subunit 4.5346E-3 9 73 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 8.8752E-12 9 376 9 6292
    cellular protein metabolic process 1.1963E-7 9 1074 9 6292
    protein metabolic process 1.9861E-7 9 1136 9 6292
    cellular macromolecule biosynthetic process 2.9528E-7 9 1187 9 6292
    macromolecule biosynthetic process 2.9981E-7 9 1189 9 6292
    gene expression 5.9596E-7 9 1283 9 6292
    cellular biosynthetic process 3.6225E-6 9 1567 9 6292
    biosynthetic process 4.4215E-6 9 1602 9 6292
    ribosomal subunit assembly 5.1163E-5 9 55 3 6292
    maturation of SSU-rRNA 6.3216E-5 9 59 3 6292
    ribosome assembly 8.0728E-5 9 64 3 6292
    organelle assembly 1.0115E-4 9 69 3 6292
    cellular macromolecule metabolic process 1.0877E-4 9 2285 9 6292
    macromolecule metabolic process 1.3953E-4 9 2349 9 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1.4073E-4 9 13 2 6292
    ribosomal small subunit assembly 1.6406E-4 9 14 2 6292
    ribonucleoprotein complex assembly 2.3847E-4 9 92 3 6292
    ribosomal small subunit biogenesis 5.8072E-4 9 26 2 6292
    rRNA processing 6.3162E-4 9 128 3 6292
    rRNA metabolic process 7.7062E-4 9 137 3 6292
    ribosome biogenesis 9.0809E-4 9 346 4 6292
    primary metabolic process 9.2081E-4 9 2896 9 6292
    ribonucleoprotein complex biogenesis 1.2185E-3 9 374 4 6292
    cellular metabolic process 1.3966E-3 9 3033 9 6292
    cellular macromolecular complex assembly 1.7584E-3 9 182 3 6292
    metabolic process 2.004E-3 9 3157 9 6292
    regulation of translation 2.7869E-3 9 57 2 6292
    ncRNA processing 2.8373E-3 9 215 3 6292
    posttranscriptional regulation of gene expression 3.186E-3 9 61 2 6292
    regulation of cellular protein metabolic process 3.9454E-3 9 68 2 6292
    regulation of protein metabolic process 4.6571E-3 9 74 2 6292
    ncRNA metabolic process 4.7107E-3 9 257 3 6292
    cellular macromolecular complex subunit organization 4.8149E-3 9 259 3 6292
    maturation of 5.8S rRNA 5.7106E-3 9 4 1 6292
    cleavage involved in rRNA processing 5.7106E-3 9 4 1 6292
    maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 5.7106E-3 9 4 1 6292
    endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 5.7106E-3 9 4 1 6292
    endonucleolytic cleavage involved in rRNA processing 5.7106E-3 9 4 1 6292
    endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 5.7106E-3 9 4 1 6292
    macromolecular complex assembly 6.0565E-3 9 281 3 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 4.7387E-14 9 212 9 6292
    structural molecule activity 3.4568E-12 9 339 9 6292
    RNA binding 7.0672E-8 9 367 7 6292
    rRNA binding 1.1231E-6 9 16 3 6292
    nucleic acid binding 4.2982E-6 9 666 7 6292
    binding 3.7284E-4 9 1294 7 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle