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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 19 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
RPL10
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • RPL11B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • RPL12B, RPL12A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • regulation of translation
  • translational termination
  • ribosomal large subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL17A
  • cytoplasm
  • translation
  • structural constituent of ribosome
  • RPL20A
  • translation
  • structural constituent of ribosome
  • RPL2A, RPL2B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • regulation of translation
  • response to drug
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPL36A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL42B, RPL42A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • response to antibiotic
  • response to cycloheximide
  • translation
  • structural constituent of ribosome
  • RPL4A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPL6A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPS11A, RPS11B
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosomal small subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS14A
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • telomere maintenance
  • ribosomal small subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPS16B, RPS16A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosomal small subunit biogenesis
  • translation
  • structural constituent of ribosome
  • RPS17B
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • intracellular
  • telomere maintenance
  • ribosomal small subunit assembly
  • translation
  • structural constituent of ribosome
  • RPS1A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • 90S preribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS3
  • preribosome, small subunit precursor
  • response to DNA damage stimulus
  • translation
  • structural constituent of ribosome
  • RPS30B, RPS30A
  • stress granule
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS5
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • small ribosomal subunit
  • 90S preribosome
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS8B, RPS8A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • 90S preribosome
  • ribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • translation
  • structural constituent of ribosome
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cytosolic ribosome 1.5183E-24 19 101 15 6292
    cytosolic part 3.1023E-23 19 122 15 6292
    ribosomal subunit 1.7799E-20 19 183 15 6292
    cytosol 1.51E-17 19 284 15 6292
    ribosome 2.0749E-17 19 290 15 6292
    ribonucleoprotein complex 3.6785E-17 19 514 17 6292
    cytosolic large ribosomal subunit 2.9396E-12 19 60 8 6292
    cytosolic small ribosomal subunit 7.82E-12 19 38 7 6292
    preribosome 4.0384E-10 19 34 6 6292
    large ribosomal subunit 4.3513E-10 19 110 8 6292
    90S preribosome 8.5763E-10 19 17 5 6292
    small ribosomal subunit 9.5191E-10 19 73 7 6292
    non-membrane-bounded organelle 1.0703E-9 19 959 15 6292
    intracellular non-membrane-bounded organelle 1.0703E-9 19 959 15 6292
    macromolecular complex 1.0334E-8 19 1635 17 6292
    organelle part 1.7905E-4 19 2282 15 6292
    intracellular organelle part 1.7905E-4 19 2282 15 6292
    cytoplasmic part 5.2775E-4 19 2482 15 6292
    stress granule 3.0197E-3 19 1 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 3.6523E-24 19 376 19 6292
    cellular protein metabolic process 2.2613E-15 19 1074 19 6292
    protein metabolic process 6.6265E-15 19 1136 19 6292
    cellular macromolecule biosynthetic process 1.5364E-14 19 1187 19 6292
    macromolecule biosynthetic process 1.5867E-14 19 1189 19 6292
    gene expression 6.8073E-14 19 1283 19 6292
    cellular biosynthetic process 3.1157E-12 19 1567 19 6292
    biosynthetic process 4.752E-12 19 1602 19 6292
    ribosomal subunit assembly 1.222E-10 19 55 7 6292
    ribosome assembly 3.6847E-10 19 64 7 6292
    organelle assembly 6.3458E-10 19 69 7 6292
    cellular macromolecule metabolic process 4.1791E-9 19 2285 19 6292
    ribonucleoprotein complex assembly 4.9567E-9 19 92 7 6292
    macromolecule metabolic process 7.078E-9 19 2349 19 6292
    ribosome biogenesis 2.3474E-7 19 346 9 6292
    primary metabolic process 3.8309E-7 19 2896 19 6292
    ribonucleoprotein complex biogenesis 4.57E-7 19 374 9 6292
    regulation of translation 5.3866E-7 19 57 5 6292
    cellular macromolecular complex assembly 5.6713E-7 19 182 7 6292
    posttranscriptional regulation of gene expression 7.5965E-7 19 61 5 6292
    ribosomal small subunit biogenesis 8.516E-7 19 26 4 6292
    cellular metabolic process 9.2442E-7 19 3033 19 6292
    regulation of cellular protein metabolic process 1.3138E-6 19 68 5 6292
    metabolic process 1.9837E-6 19 3157 19 6292
    regulation of protein metabolic process 2.0076E-6 19 74 5 6292
    ribosomal large subunit assembly 5.6055E-6 19 41 4 6292
    cellular macromolecular complex subunit organization 6.084E-6 19 259 7 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 6.5522E-6 19 13 3 6292
    ribosomal small subunit assembly 8.3233E-6 19 14 3 6292
    macromolecular complex assembly 1.0432E-5 19 281 7 6292
    maturation of SSU-rRNA 2.4339E-5 19 59 4 6292
    ribosomal large subunit biogenesis 3.5792E-5 19 65 4 6292
    macromolecular complex subunit organization 4.965E-5 19 357 7 6292
    cellular component biogenesis 7.6241E-5 19 694 9 6292
    cellular component assembly 8.0565E-5 19 385 7 6292
    rRNA processing 4.9974E-4 19 128 4 6292
    rRNA metabolic process 6.466E-4 19 137 4 6292
    cellular process 1.2366E-3 19 4426 19 6292
    response to cycloheximide 3.0197E-3 19 1 1 6292
    response to cycloalkane 3.0197E-3 19 1 1 6292
    response to organic cyclic substance 3.0197E-3 19 1 1 6292
    ncRNA processing 3.4298E-3 19 215 4 6292
    ncRNA metabolic process 6.4867E-3 19 257 4 6292
    regulation of gene expression 8.7726E-3 19 445 5 6292
    response to antibiotic 9.0332E-3 19 3 1 6292
    regulation of macromolecule biosynthetic process 9.7098E-3 19 456 5 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 4.7233E-29 19 212 19 6292
    structural molecule activity 4.8468E-25 19 339 19 6292
    RNA binding 5.3539E-4 19 367 6 6292
    rRNA binding 1.011E-3 19 16 2 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle