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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 21 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
RPL10
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • RPL11B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • RPL12B, RPL12A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • regulation of translation
  • translational termination
  • ribosomal large subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL17A
  • cytoplasm
  • translation
  • structural constituent of ribosome
  • RPL18A, RPL18B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • regulation of translation
  • translation
  • structural constituent of ribosome
  • RPL20A
  • translation
  • structural constituent of ribosome
  • RPL2A, RPL2B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • regulation of translation
  • response to drug
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPL3
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • RPL36A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL42B, RPL42A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • response to antibiotic
  • response to cycloheximide
  • translation
  • structural constituent of ribosome
  • RPL4A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPL6A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPS14A
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • telomere maintenance
  • ribosomal small subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPS16B, RPS16A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosomal small subunit biogenesis
  • translation
  • structural constituent of ribosome
  • RPS17B
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • intracellular
  • telomere maintenance
  • ribosomal small subunit assembly
  • translation
  • structural constituent of ribosome
  • RPS1A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • 90S preribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS2
  • small nucleolar ribonucleoprotein complex
  • regulation of translational fidelity
  • translation
  • structural constituent of ribosome
  • RPS3
  • preribosome, small subunit precursor
  • response to DNA damage stimulus
  • translation
  • structural constituent of ribosome
  • RPS30B, RPS30A
  • stress granule
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS5
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • small ribosomal subunit
  • 90S preribosome
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS8B, RPS8A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • 90S preribosome
  • ribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • translation
  • structural constituent of ribosome
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cytosolic ribosome 1.0786E-25 21 101 16 6292
    cytosolic part 2.7331E-24 21 122 16 6292
    ribosomal subunit 2.4387E-21 21 183 16 6292
    ribonucleoprotein complex 2.8276E-19 21 514 19 6292
    cytosol 3.2606E-18 21 284 16 6292
    ribosome 4.5758E-18 21 290 16 6292
    cytosolic large ribosomal subunit 9.2265E-16 21 60 10 6292
    large ribosomal subunit 5.2956E-13 21 110 10 6292
    non-membrane-bounded organelle 7.2426E-10 21 959 16 6292
    intracellular non-membrane-bounded organelle 7.2426E-10 21 959 16 6292
    macromolecular complex 8.406E-10 21 1635 19 6292
    cytosolic small ribosomal subunit 1.6318E-9 21 38 6 6292
    preribosome 6.4886E-8 21 34 5 6292
    small ribosomal subunit 9.3631E-8 21 73 6 6292
    90S preribosome 2.1227E-7 21 17 4 6292
    organelle part 2.2313E-4 21 2282 16 6292
    intracellular organelle part 2.2313E-4 21 2282 16 6292
    cytoplasmic part 6.8308E-4 21 2482 16 6292
    stress granule 3.3376E-3 21 1 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 1.1798E-26 21 376 21 6292
    cellular protein metabolic process 6.3911E-17 21 1074 21 6292
    protein metabolic process 2.0995E-16 21 1136 21 6292
    cellular macromolecule biosynthetic process 5.3227E-16 21 1187 21 6292
    macromolecule biosynthetic process 5.5159E-16 21 1189 21 6292
    gene expression 2.7621E-15 21 1283 21 6292
    cellular biosynthetic process 1.8964E-13 21 1567 21 6292
    biosynthetic process 3.0247E-13 21 1602 21 6292
    ribosomal subunit assembly 2.7825E-10 21 55 7 6292
    cellular macromolecule metabolic process 5.4516E-10 21 2285 21 6292
    ribosome assembly 8.3688E-10 21 64 7 6292
    macromolecule metabolic process 9.7623E-10 21 2349 21 6292
    organelle assembly 1.4392E-9 21 69 7 6292
    ribonucleoprotein complex assembly 1.117E-8 21 92 7 6292
    regulation of translation 2.0628E-8 21 57 6 6292
    posttranscriptional regulation of gene expression 3.1304E-8 21 61 6 6292
    regulation of cellular protein metabolic process 6.0825E-8 21 68 6 6292
    primary metabolic process 8.0566E-8 21 2896 21 6292
    regulation of protein metabolic process 1.0168E-7 21 74 6 6292
    ribosomal large subunit assembly 1.7217E-7 21 41 5 6292
    cellular metabolic process 2.1337E-7 21 3033 21 6292
    metabolic process 4.9632E-7 21 3157 21 6292
    ribosome biogenesis 6.768E-7 21 346 9 6292
    cellular macromolecular complex assembly 1.246E-6 21 182 7 6292
    ribonucleoprotein complex biogenesis 1.3067E-6 21 374 9 6292
    ribosomal large subunit biogenesis 1.803E-6 21 65 5 6292
    cellular macromolecular complex subunit organization 1.3078E-5 21 259 7 6292
    macromolecular complex assembly 2.2284E-5 21 281 7 6292
    ribosomal small subunit biogenesis 7.9315E-5 21 26 3 6292
    macromolecular complex subunit organization 1.0378E-4 21 357 7 6292
    cellular component assembly 1.6705E-4 21 385 7 6292
    cellular component biogenesis 1.9779E-4 21 694 9 6292
    cellular process 6.1031E-4 21 4426 21 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 8.0949E-4 21 13 2 6292
    maturation of SSU-rRNA 9.2387E-4 21 59 3 6292
    ribosomal small subunit assembly 9.4251E-4 21 14 2 6292
    regulation of gene expression 2.6292E-3 21 445 6 6292
    regulation of macromolecule biosynthetic process 2.9759E-3 21 456 6 6292
    response to cycloheximide 3.3376E-3 21 1 1 6292
    response to cycloalkane 3.3376E-3 21 1 1 6292
    response to organic cyclic substance 3.3376E-3 21 1 1 6292
    regulation of cellular biosynthetic process 3.5411E-3 21 472 6 6292
    regulation of biosynthetic process 3.5789E-3 21 473 6 6292
    regulation of macromolecule metabolic process 4.1841E-3 21 488 6 6292
    regulation of primary metabolic process 5.4121E-3 21 514 6 6292
    regulation of cellular metabolic process 6.6466E-3 21 536 6 6292
    regulation of metabolic process 7.3369E-3 21 547 6 6292
    rRNA processing 8.3671E-3 21 128 3 6292
    response to antibiotic 9.9809E-3 21 3 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 4.4486E-32 21 212 21 6292
    structural molecule activity 1.2575E-27 21 339 21 6292
    RNA binding 6.1472E-3 21 367 5 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle