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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 17 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
RPL12B, RPL12A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • regulation of translation
  • translational termination
  • ribosomal large subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL17A
  • cytoplasm
  • translation
  • structural constituent of ribosome
  • RPL20A
  • translation
  • structural constituent of ribosome
  • RPL24A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL2A, RPL2B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • regulation of translation
  • response to drug
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPL3
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • RPL31B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPL32
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPL36A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL42B, RPL42A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • response to antibiotic
  • response to cycloheximide
  • translation
  • structural constituent of ribosome
  • RPL4A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPL9A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS14A
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • telomere maintenance
  • ribosomal small subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPS16B, RPS16A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosomal small subunit biogenesis
  • translation
  • structural constituent of ribosome
  • RPS17B
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • intracellular
  • telomere maintenance
  • ribosomal small subunit assembly
  • translation
  • structural constituent of ribosome
  • RPS5
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • small ribosomal subunit
  • 90S preribosome
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS9B
  • small nucleolar ribonucleoprotein complex
  • regulation of translational fidelity
  • translation
  • structural constituent of ribosome
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cytosolic ribosome 4.797E-21 17 101 13 6292
    cytosolic part 6.3752E-20 17 122 13 6292
    ribosomal subunit 1.4992E-17 17 183 13 6292
    cytosolic large ribosomal subunit 5.2374E-17 17 60 10 6292
    ribonucleoprotein complex 4.6406E-15 17 514 15 6292
    cytosol 4.9973E-15 17 284 13 6292
    ribosome 6.5721E-15 17 290 13 6292
    large ribosomal subunit 3.0952E-14 17 110 10 6292
    non-membrane-bounded organelle 2.9132E-8 17 959 13 6292
    intracellular non-membrane-bounded organelle 2.9132E-8 17 959 13 6292
    macromolecular complex 1.2396E-7 17 1635 15 6292
    cytosolic small ribosomal subunit 1.3039E-4 17 38 3 6292
    organelle part 8.5928E-4 17 2282 13 6292
    intracellular organelle part 8.5928E-4 17 2282 13 6292
    small ribosomal subunit 9.0665E-4 17 73 3 6292
    90S preribosome 9.1252E-4 17 17 2 6292
    cytoplasmic part 2.1458E-3 17 2482 13 6292
    preribosome 3.6639E-3 17 34 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 1.1188E-21 17 376 17 6292
    cellular protein metabolic process 7.9759E-14 17 1074 17 6292
    protein metabolic process 2.0853E-13 17 1136 17 6292
    cellular macromolecule biosynthetic process 4.4224E-13 17 1187 17 6292
    macromolecule biosynthetic process 4.5517E-13 17 1189 17 6292
    gene expression 1.6734E-12 17 1283 17 6292
    cellular biosynthetic process 5.109E-11 17 1567 17 6292
    biosynthetic process 7.4517E-11 17 1602 17 6292
    cellular macromolecule metabolic process 3.1999E-8 17 2285 17 6292
    macromolecule metabolic process 5.1262E-8 17 2349 17 6292
    primary metabolic process 1.8202E-6 17 2896 17 6292
    cellular metabolic process 4.0023E-6 17 3033 17 6292
    metabolic process 7.9234E-6 17 3157 17 6292
    ribosomal subunit assembly 1.1433E-5 17 55 4 6292
    regulation of translation 1.3198E-5 17 57 4 6292
    posttranscriptional regulation of gene expression 1.732E-5 17 61 4 6292
    ribosome assembly 2.0983E-5 17 64 4 6292
    regulation of cellular protein metabolic process 2.6716E-5 17 68 4 6292
    organelle assembly 2.8313E-5 17 69 4 6292
    regulation of protein metabolic process 3.7372E-5 17 74 4 6292
    ribosomal small subunit biogenesis 4.1E-5 17 26 3 6292
    ribonucleoprotein complex assembly 8.8077E-5 17 92 4 6292
    ribosomal small subunit assembly 6.135E-4 17 14 2 6292
    cellular macromolecular complex assembly 1.1997E-3 17 182 4 6292
    ribosome biogenesis 1.7448E-3 17 346 5 6292
    ribonucleoprotein complex biogenesis 2.4643E-3 17 374 5 6292
    cellular process 2.5051E-3 17 4426 17 6292
    response to cycloheximide 2.7018E-3 17 1 1 6292
    response to cycloalkane 2.7018E-3 17 1 1 6292
    response to organic cyclic substance 2.7018E-3 17 1 1 6292
    cellular macromolecular complex subunit organization 4.3673E-3 17 259 4 6292
    ribosomal large subunit assembly 5.2962E-3 17 41 2 6292
    macromolecular complex assembly 5.8421E-3 17 281 4 6292
    response to antibiotic 8.0849E-3 17 3 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 4.9155E-26 17 212 17 6292
    structural molecule activity 1.8461E-22 17 339 17 6292
    RNA binding 2.267E-3 17 367 5 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle