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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 11 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
KRE33
  • nucleolus
  • ribosome biogenesis
  • molecular_function
  • RPL15A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL20B
  • ribosome biogenesis
  • translation
  • structural constituent of ribosome
  • RPS11A, RPS11B
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosomal small subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS1B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • 90S preribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS24A, RPS24B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • mitochondrion
  • ribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • translation
  • nucleotide binding
  • structural constituent of ribosome
  • RPS3
  • preribosome, small subunit precursor
  • response to DNA damage stimulus
  • translation
  • structural constituent of ribosome
  • RPS4B, RPS4A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS7A
  • small nucleolar ribonucleoprotein complex
  • translation
  • structural constituent of ribosome
  • RPS8B, RPS8A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • 90S preribosome
  • ribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • translation
  • structural constituent of ribosome
  • UTP22
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    preribosome 1.531E-9 11 34 5 6292
    cytosolic small ribosomal subunit 2.753E-9 11 38 5 6292
    cytosolic ribosome 6.3807E-9 11 101 6 6292
    ribonucleoprotein complex 7.1884E-9 11 514 9 6292
    90S preribosome 1.1899E-8 11 17 4 6292
    cytosolic part 2.0058E-8 11 122 6 6292
    small ribosomal subunit 8.0106E-8 11 73 5 6292
    ribosomal subunit 2.2839E-7 11 183 6 6292
    cytosol 3.0618E-6 11 284 6 6292
    ribosome 3.4601E-6 11 290 6 6292
    non-membrane-bounded organelle 3.0414E-5 11 959 8 6292
    intracellular non-membrane-bounded organelle 3.0414E-5 11 959 8 6292
    macromolecular complex 1.7215E-4 11 1635 9 6292
    small nucleolar ribonucleoprotein complex 6.6441E-3 11 72 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 4.3817E-10 11 376 9 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 3.5876E-9 11 13 4 6292
    gene expression 1.0844E-6 11 1283 10 6292
    regulation of translation 1.9056E-6 11 57 4 6292
    maturation of SSU-rRNA 2.1917E-6 11 59 4 6292
    posttranscriptional regulation of gene expression 2.5085E-6 11 61 4 6292
    regulation of cellular protein metabolic process 3.8902E-6 11 68 4 6292
    cellular protein metabolic process 4.7266E-6 11 1074 9 6292
    regulation of protein metabolic process 5.4669E-6 11 74 4 6292
    protein metabolic process 7.6839E-6 11 1136 9 6292
    ribosome biogenesis 9.6734E-6 11 346 6 6292
    cellular macromolecule biosynthetic process 1.1227E-5 11 1187 9 6292
    macromolecule biosynthetic process 1.1391E-5 11 1189 9 6292
    ribonucleoprotein complex biogenesis 1.5174E-5 11 374 6 6292
    rRNA processing 4.8284E-5 11 128 4 6292
    rRNA metabolic process 6.305E-5 11 137 4 6292
    cellular biosynthetic process 1.2033E-4 11 1567 9 6292
    biosynthetic process 1.4499E-4 11 1602 9 6292
    cellular macromolecule metabolic process 2.9073E-4 11 2285 10 6292
    ncRNA processing 3.6214E-4 11 215 4 6292
    macromolecule metabolic process 3.7814E-4 11 2349 10 6292
    cellular component biogenesis 4.9969E-4 11 694 6 6292
    ncRNA metabolic process 7.1489E-4 11 257 4 6292
    primary metabolic process 2.7104E-3 11 2896 10 6292
    RNA processing 3.0756E-3 11 380 4 6292
    cellular metabolic process 4.1594E-3 11 3033 10 6292
    regulation of gene expression 5.4589E-3 11 445 4 6292
    regulation of macromolecule biosynthetic process 5.9597E-3 11 456 4 6292
    metabolic process 6.0149E-3 11 3157 10 6292
    regulation of cellular biosynthetic process 6.7432E-3 11 472 4 6292
    regulation of biosynthetic process 6.7944E-3 11 473 4 6292
    regulation of macromolecule metabolic process 7.5943E-3 11 488 4 6292
    regulation of primary metabolic process 9.1283E-3 11 514 4 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 2.4569E-12 11 212 9 6292
    structural molecule activity 1.7258E-10 11 339 9 6292
    rRNA binding 3.2905E-4 11 16 2 6292
    RNA binding 2.7066E-3 11 367 4 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle