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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 8 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
ECM16
  • mitochondrion
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • RNA helicase activity
  • KRE33
  • nucleolus
  • ribosome biogenesis
  • molecular_function
  • RPS11A, RPS11B
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosomal small subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS13
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • 90S preribosome
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS4B, RPS4A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS8B, RPS8A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • 90S preribosome
  • ribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • translation
  • structural constituent of ribosome
  • TSR1
  • cytoplasm
  • nucleolus
  • ribosome biogenesis
  • rRNA processing
  • ribonucleoprotein binding
  • UTP22
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    90S preribosome 2.5367E-9 8 17 4 6292
    preribosome 4.9003E-8 8 34 4 6292
    cytosolic small ribosomal subunit 7.7836E-8 8 38 4 6292
    non-membrane-bounded organelle 2.8409E-7 8 959 8 6292
    intracellular non-membrane-bounded organelle 2.8409E-7 8 959 8 6292
    small ribosomal subunit 1.1273E-6 8 73 4 6292
    cytosolic ribosome 4.1685E-6 8 101 4 6292
    ribonucleoprotein complex 7.018E-6 8 514 6 6292
    cytosolic part 8.871E-6 8 122 4 6292
    ribosomal subunit 4.4245E-5 8 183 4 6292
    nucleolus 7.7406E-5 8 211 4 6292
    cytosol 2.4634E-4 8 284 4 6292
    ribosome 2.671E-4 8 290 4 6292
    organelle part 2.9704E-4 8 2282 8 6292
    intracellular organelle part 2.9704E-4 8 2282 8 6292
    nuclear lumen 1.4695E-3 8 453 4 6292
    small nucleolar ribonucleoprotein complex 3.4584E-3 8 72 2 6292
    macromolecular complex 5.1894E-3 8 1635 6 6292
    organelle lumen 5.9438E-3 8 660 4 6292
    intracellular organelle lumen 5.9438E-3 8 660 4 6292
    membrane-enclosed lumen 7.3614E-3 8 700 4 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    rRNA processing 1.7189E-7 8 128 5 6292
    rRNA metabolic process 2.4182E-7 8 137 5 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 3.8367E-7 8 13 3 6292
    maturation of SSU-rRNA 4.7479E-7 8 59 4 6292
    ribosome biogenesis 6.7573E-7 8 346 6 6292
    ribonucleoprotein complex biogenesis 1.0727E-6 8 374 6 6292
    ncRNA processing 2.291E-6 8 215 5 6292
    ncRNA metabolic process 5.5383E-6 8 257 5 6292
    RNA processing 3.7674E-5 8 380 5 6292
    regulation of translation 3.8233E-5 8 57 3 6292
    cellular component biogenesis 4.0619E-5 8 694 6 6292
    posttranscriptional regulation of gene expression 4.6914E-5 8 61 3 6292
    regulation of cellular protein metabolic process 6.5054E-5 8 68 3 6292
    regulation of protein metabolic process 8.3843E-5 8 74 3 6292
    gene expression 9.518E-5 8 1283 7 6292
    translation 7.2474E-4 8 376 4 6292
    RNA metabolic process 2.9766E-3 8 954 5 6292
    cellular macromolecule metabolic process 4.5244E-3 8 2285 7 6292
    macromolecule metabolic process 5.4192E-3 8 2349 7 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 7.8854E-5 8 212 4 6292
    rRNA binding 1.6826E-4 8 16 2 6292
    structural molecule activity 4.8751E-4 8 339 4 6292
    RNA binding 8.8446E-3 8 367 3 6292
    ribonucleoprotein binding 8.8705E-3 8 7 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle