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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 9 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
KEM1
  • cytoplasm
  • cytoplasmic mRNA processing body
  • nuclear outer membrane
  • filamentous growth
  • response to exogenous dsRNA
  • telomere maintenance
  • traversing start control point of mitotic cell cycle
  • karyogamy involved in conjugation with cellular fusion
  • mRNA catabolic process
  • 5'-3' exoribonuclease activity
  • deoxyribonuclease activity
  • recombinase activity
  • RPL15A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL20B
  • ribosome biogenesis
  • translation
  • structural constituent of ribosome
  • RPS11A, RPS11B
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosomal small subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS13
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • 90S preribosome
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS4B, RPS4A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS8B, RPS8A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • 90S preribosome
  • ribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • translation
  • structural constituent of ribosome
  • STM1
  • cytoplasm
  • nuclear telomere cap complex
  • anti-apoptosis
  • telomere maintenance
  • DNA binding
  • telomeric DNA binding
  • UTP22
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    90S preribosome 4.5585E-9 9 17 4 6292
    preribosome 8.7868E-8 9 34 4 6292
    cytosolic ribosome 1.1557E-7 9 101 5 6292
    cytosolic small ribosomal subunit 1.395E-7 9 38 4 6292
    cytosolic part 2.9904E-7 9 122 5 6292
    ribonucleoprotein complex 7.2713E-7 9 514 7 6292
    small ribosomal subunit 2.0114E-6 9 73 4 6292
    ribosomal subunit 2.2594E-6 9 183 5 6292
    cytosol 1.9632E-5 9 284 5 6292
    ribosome 2.174E-5 9 290 5 6292
    non-membrane-bounded organelle 5.0826E-5 9 959 7 6292
    intracellular non-membrane-bounded organelle 5.0826E-5 9 959 7 6292
    macromolecular complex 1.4222E-4 9 1635 8 6292
    intracellular organelle part 1.8134E-3 9 2282 8 6292
    organelle part 1.8134E-3 9 2282 8 6292
    nuclear outer membrane 6.2461E-3 9 86 2 6292
    nuclear membrane 7.8919E-3 9 97 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 5.7481E-7 9 13 3 6292
    translation 3.1544E-6 9 376 6 6292
    regulation of translation 5.698E-5 9 57 3 6292
    maturation of SSU-rRNA 6.3216E-5 9 59 3 6292
    posttranscriptional regulation of gene expression 6.9885E-5 9 61 3 6292
    regulation of cellular protein metabolic process 9.6826E-5 9 68 3 6292
    cellular macromolecule metabolic process 1.0877E-4 9 2285 9 6292
    regulation of protein metabolic process 1.247E-4 9 74 3 6292
    macromolecule metabolic process 1.3953E-4 9 2349 9 6292
    gene expression 3.5247E-4 9 1283 7 6292
    rRNA processing 6.3162E-4 9 128 3 6292
    rRNA metabolic process 7.7062E-4 9 137 3 6292
    ribosome biogenesis 9.0809E-4 9 346 4 6292
    primary metabolic process 9.2081E-4 9 2896 9 6292
    ribonucleoprotein complex biogenesis 1.2185E-3 9 374 4 6292
    cellular protein metabolic process 1.283E-3 9 1074 6 6292
    cellular metabolic process 1.3966E-3 9 3033 9 6292
    negative regulation of programmed cell death 1.4304E-3 9 1 1 6292
    negative regulation of cell death 1.4304E-3 9 1 1 6292
    anti-apoptosis 1.4304E-3 9 1 1 6292
    negative regulation of apoptosis 1.4304E-3 9 1 1 6292
    protein metabolic process 1.7457E-3 9 1136 6 6292
    metabolic process 2.004E-3 9 3157 9 6292
    cellular macromolecule biosynthetic process 2.2182E-3 9 1187 6 6292
    macromolecule biosynthetic process 2.2386E-3 9 1189 6 6292
    regulation of cellular process 2.599E-3 9 796 5 6292
    ncRNA processing 2.8373E-3 9 215 3 6292
    regulation of biological process 3.0404E-3 9 824 5 6292
    ncRNA metabolic process 4.7107E-3 9 257 3 6292
    regulation of programmed cell death 5.7106E-3 9 4 1 6292
    regulation of cell death 5.7106E-3 9 4 1 6292
    regulation of apoptosis 5.7106E-3 9 4 1 6292
    traversing start control point of mitotic cell cycle 8.5551E-3 9 6 1 6292
    cellular biosynthetic process 9.7492E-3 9 1567 6 6292
    response to exogenous dsRNA 9.9746E-3 9 7 1 6292
    response to dsRNA 9.9746E-3 9 7 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 1.0532E-7 9 212 6 6292
    structural molecule activity 1.7138E-6 9 339 6 6292
    rRNA binding 2.1602E-4 9 16 2 6292
    RNA binding 1.1347E-3 9 367 4 6292
    nucleic acid binding 1.1464E-3 9 666 5 6292
    5'-3' exoribonuclease activity 2.859E-3 9 2 1 6292
    recombinase activity 5.7106E-3 9 4 1 6292
    5'-3' exonuclease activity 8.5551E-3 9 6 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle