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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 8 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

U5 snRNP 4.8801E-7 8 14 3 6292
small nuclear ribonucleoprotein complex 6.2013E-7 8 63 4 6292
U4/U6 x U5 tri-snRNP complex 6.5787E-6 8 32 3 6292
ribonucleoprotein complex 7.018E-6 8 514 6 6292
spliceosomal complex 1.8675E-5 8 45 3 6292
U1 snRNP 1.9058E-4 8 17 2 6292
nuclear part 5.8147E-4 8 1103 6 6292
nucleus 2.1521E-3 8 2041 7 6292
organelle part 4.4856E-3 8 2282 7 6292
intracellular organelle part 4.4856E-3 8 2282 7 6292
macromolecular complex 5.1894E-3 8 1635 6 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

RNA splicing 3.036E-14 8 132 8 6292
nuclear mRNA splicing, via spliceosome 1.5229E-12 8 99 7 6292
RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 1.6372E-12 8 100 7 6292
RNA splicing, via transesterification reactions 2.6644E-12 8 107 7 6292
mRNA processing 3.9491E-11 8 156 7 6292
RNA processing 1.6507E-10 8 380 8 6292
mRNA metabolic process 3.5957E-10 8 213 7 6292
RNA metabolic process 2.7241E-7 8 954 8 6292
gene expression 2.9372E-6 8 1283 8 6292
nucleic acid metabolic process 6.4427E-6 8 1415 8 6292
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 1.4527E-5 8 1566 8 6292
cellular nitrogen compound metabolic process 3.8773E-5 8 1770 8 6292
nitrogen compound metabolic process 4.2618E-5 8 1791 8 6292
ribonucleoprotein complex assembly 1.6068E-4 8 92 3 6292
spliceosome assembly 2.1426E-4 8 18 2 6292
cellular macromolecule metabolic process 3.0018E-4 8 2285 8 6292
macromolecule metabolic process 3.7455E-4 8 2349 8 6292
cellular macromolecular complex assembly 1.1976E-3 8 182 3 6292
primary metabolic process 2.0036E-3 8 2896 8 6292
cis assembly of pre-catalytic spliceosome 2.5415E-3 8 2 1 6292
cellular metabolic process 2.9013E-3 8 3033 8 6292
cellular macromolecular complex subunit organization 3.31E-3 8 259 3 6292
nuclear mRNA cis splicing, via spliceosome 3.8101E-3 8 3 1 6292
generation of catalytic spliceosome for first transesterification step 3.8101E-3 8 3 1 6292
metabolic process 3.9991E-3 8 3157 8 6292
macromolecular complex assembly 4.1746E-3 8 281 3 6292
macromolecular complex subunit organization 8.1895E-3 8 357 3 6292
ribonucleoprotein complex biogenesis 9.3216E-3 8 374 3 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

snRNA binding 1.4121E-5 8 5 2 6292
RNA binding 3.1798E-5 8 367 5 6292
nucleic acid binding 5.58E-4 8 666 5 6292
U2 snRNA binding 1.2715E-3 8 1 1 6292
binding 1.4278E-3 8 1294 6 6292
U5 snRNA binding 2.5415E-3 8 2 1 6292
first spliceosomal transesterification activity 7.6075E-3 8 6 1 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle