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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 17 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
IMG1
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • IMG2
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • telomere maintenance
  • translation
  • structural constituent of ribosome
  • MHR1
  • nucleus
  • mitochondrion
  • mitochondrial genome maintenance
  • transcription regulator activity
  • MRP7
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • peptidyltransferase activity
  • MRPL1
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • aerobic respiration
  • translation
  • structural constituent of ribosome
  • MRPL16
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • peptidyltransferase activity
  • MRPL17
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL20
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • mitochondrial genome maintenance
  • translation
  • structural constituent of ribosome
  • MRPL23
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • MRPL28
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL3
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL35
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL36
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL4
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL7
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL8
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • mitochondrial genome maintenance
  • translation
  • structural constituent of ribosome
  • YML6
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    organellar large ribosomal subunit 2.9431E-34 17 50 16 6292
    mitochondrial large ribosomal subunit 2.9431E-34 17 50 16 6292
    organellar ribosome 1.2754E-29 17 90 16 6292
    mitochondrial ribosome 1.2754E-29 17 90 16 6292
    large ribosomal subunit 4.1352E-28 17 110 16 6292
    mitochondrial matrix 1.1764E-24 17 176 16 6292
    mitochondrial lumen 1.1764E-24 17 176 16 6292
    ribosomal subunit 2.255E-24 17 183 16 6292
    ribosome 4.5213E-21 17 290 16 6292
    mitochondrial part 1.391E-17 17 475 16 6292
    ribonucleoprotein complex 4.9819E-17 17 514 16 6292
    organelle lumen 2.7998E-15 17 660 16 6292
    intracellular organelle lumen 2.7998E-15 17 660 16 6292
    membrane-enclosed lumen 7.2058E-15 17 700 16 6292
    mitochondrion 1.7653E-13 17 1125 17 6292
    non-membrane-bounded organelle 1.1127E-12 17 959 16 6292
    intracellular non-membrane-bounded organelle 1.1127E-12 17 959 16 6292
    macromolecular complex 5.268E-9 17 1635 16 6292
    cytoplasmic part 1.3115E-7 17 2482 17 6292
    organelle part 9.7262E-7 17 2282 16 6292
    intracellular organelle part 9.7262E-7 17 2282 16 6292
    cytoplasm 5.9071E-5 17 3552 17 6292
    membrane-bounded organelle 1.6371E-4 17 3771 17 6292
    intracellular membrane-bounded organelle 1.6371E-4 17 3771 17 6292
    intracellular organelle 6.0057E-4 17 4070 17 6292
    organelle 6.0308E-4 17 4071 17 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 3.1367E-19 17 376 16 6292
    cellular protein metabolic process 6.767E-12 17 1074 16 6292
    protein metabolic process 1.6528E-11 17 1136 16 6292
    cellular macromolecule biosynthetic process 3.3217E-11 17 1187 16 6292
    macromolecule biosynthetic process 3.4118E-11 17 1189 16 6292
    gene expression 1.1414E-10 17 1283 16 6292
    cellular biosynthetic process 2.697E-9 17 1567 16 6292
    biosynthetic process 3.8206E-9 17 1602 16 6292
    cellular macromolecule metabolic process 9.9267E-7 17 2285 16 6292
    macromolecule metabolic process 1.5241E-6 17 2349 16 6292
    primary metabolic process 3.8308E-5 17 2896 16 6292
    cellular metabolic process 7.7499E-5 17 3033 16 6292
    mitochondrial genome maintenance 9.3109E-5 17 34 3 6292
    metabolic process 1.4236E-4 17 3157 16 6292
    cellular process 2.5051E-3 17 4426 17 6292
    ribosomal large subunit assembly 5.2962E-3 17 41 2 6292
    mitochondrion organization 7.874E-3 17 156 3 6292
    ribosomal subunit assembly 9.3809E-3 17 55 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 2.5971E-23 17 212 16 6292
    structural molecule activity 5.8026E-20 17 339 16 6292
    peptidyltransferase activity 2.0582E-5 17 3 2 6292
    transferase activity, transferring amino-acyl groups 6.8389E-5 17 5 2 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle