Protein Overview: P4HA1_RAT

General Information:
Name(s) found:	P4HA1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|90111077\|sp\|P54001.2\|P4HA1_RAT RecName: Full=Prolyl 4-hydroxylase subunit alpha-1; AltName: Full=4-PH alpha-1; AltName: Full=Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1; Flags: Precursor [NCBI NR] gi\|51036657\|ref\|NP_742059.2\| procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide I [Rattus norvegicus] [NCBI NR] gi\|50927553\|gb\|AAH78703.1\| Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide I [Rattus norvegicus] [NCBI NR] gi\|149038787\|gb\|EDL93076.1\| procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide, isoform CRA_a [Rattus norvegicus] [NCBI NR] Prolyl 4-hydroxylase subunit alpha-1 OS=Rattus norvegicus GN=P4ha1 PE=2 SV=2 [Swiss-Prot] prolyl 4-hydroxylase alpha subunit [071204_hmrz_cont.fasta] prolyl 4-hydroxylase alpha subunit [Rattus norvegicus]gi\|50927553\|gb\|AAH78703.1\| Prolyl 4-hydroxylase alpha subunit [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Prolyl 4-hydroxylase alpha-1 subunit precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Tax_Id=10116 Procollagen-proline, 2-oxoglutarate 4-dioxygenase (Proline 4- hydroxylase), alpha 1 polypeptide [EBI-IPI_rat_3.08_07-12-2005_origrev_con.fasta] Prolyl 4-hydroxylase subunit alpha-1 precursor (4-PH alpha-1) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide I [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta] Prolyl 4-hydroxylase alpha-1 subunit precursor (4-PH alpha-1) (Procollagen-proline,2-oxoglutarate-4-dioxygenase alpha-1 subunit) [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=P4ha1 Prolyl 4-hydroxylase subunit alpha-1 [rat-ipi-250309-contam.fasta] Prolyl 4-hydroxylase subunit alpha-1 OS=Rattus norvegicus GN=P4ha1 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	534 amino acids
Gene Ontology:
Cellular Component:	endoplasmic reticulum lumen [IEA] mitochondrion [UNKNOWN] endoplasmic reticulum [UNKNOWN][IEA]
Biological Process:	oxidation reduction [IEA] collagen fibril organization [UNKNOWN] peptidyl-proline hydroxylation to 4-hydroxy-L-proline [UNKNOWN][TAS]
Molecular Function:	procollagen-proline 4-dioxygenase activity [UNKNOWN][TAS] L-ascorbic acid binding [IEA] oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [IEA] iron ion binding [IEA] oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [IEA] metal ion binding [IEA] binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIWGVLMMGI LLPQCSAHPG FFTSIGQMTD LIHNEKDLVT SLKDYIKAEE DKLEQIKKWA  60
   61 EKLDRLTSTA TKDPEGFVGH PVNAFKLMKR LNTEWSELEN LILKDMSDGF ISNLTIQRQY 120
  121 FPNDEDQVGA AKALFRLQDT YNLDTNTISK GNLPGVKHKS FLTAEDCFEL GKVAYTEADY 180
  181 YHTELWMEQA LMQLEEGEMS TVDKVSVLDY LSYAVYQQGD LDKALLLTKK LLELDPEHQR 240
  241 ANGNLVYFEY IMSKEKDANK SASGDQSDQK TTPKKKGIAV DYLPERQKYE MLCRGEGIKM 300
  301 TPRRQKRLFC RYHDGNRNPK FILAPAKQED EWDKPRIIRF HDIISDAEIE IVKDLAKPRL 360
  361 SRATVHDPET GKLTTAQYRV SKSAWLSGYE DPVVSRINMR IQDLTGLDVS TAEELQVANY 420
  421 GVGGQYEPHF DFARKDEPDA FRELGTGNRI ATWLFYMSDV SAGGATVFPE VGASVWPKKG 480
  481 TAVFWYNLFA SGEGDYSTRH AACPVLVGNK WVSNKWLHER GQEFRRPCTL SELE

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: P4HA1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: