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Protein Overview: PRPS1_RAT

General Information:
Name(s) found: PRPS1_RAT [Swiss-Prot]
Description(s) found:
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  • gi|8394053|ref|NP_058939.1| phosphoribosyl pyrophosphate synthetase 1 [Rattus norvegicus] [NCBI NR]
  • pir||KIRTR1 ribose-phosphate diphosphokinase (EC 2.7.6.1) catalytic chain I - rat [NCBI NR]
  • gi|56977|emb|CAA34555.1| unnamed protein product [Rattus norvegicus] [NCBI NR]
  • gi|50927633|gb|AAH78853.1| Prps1 protein [Rattus norvegicus] [NCBI NR]
  • gi|46397469|sp|P60892.2|PRPS1_RAT RecName: Full=Ribose-phosphate pyrophosphokinase 1; AltName: Full=Phosphoribosyl pyrophosphate synthetase I; Short=PRS-I [NCBI NR]
  • gi|206432|gb|AAA41963.1| phosphoribosyl pyrophosphate synthetase I [NCBI NR]
  • gi|206426|gb|AAA41960.1| phosphoribosylpyrophosphate synthetase (PRPS1) precursor [NCBI NR]
  • gi|206424|gb|AAA41959.1| phosphoribosylpyrophosphate synthetase [NCBI NR]
  • gi|149022075|gb|EDL78969.1| rCG27134, isoform CRA_a [Rattus norvegicus] [NCBI NR]
  • Ribose-phosphate pyrophosphokinase 1 OS=Rattus norvegicus GN=Prps1 PE=1 SV=2 [Swiss-Prot]
  • phosphoribosyl pyrophosphate synthetase 1 [HMR_022704-rand.fasta]
  • phosphoribosyl pyrophosphate synthetase 1 [Rattus norvegicus]gi|10946854|ref|NP_067438.1| phosphoribosyl pyrophosphate synthetase 1 [Mus musculus]gi|4506127|ref|NP_002755.1| phosphoribosyl pyrophosphate synthetase 1 [Homo sapiens]gi|50927633|gb|AAH7885 [nrdb_11152004_Chlamydomonas]
  • (NM_017243) phosphoribosyl pyrophosphate synthetase 1 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • phosphoribosyl pyrophosphate synthetase 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Ribose-phosphate pyrophosphokinase 1 (Phosphoribosyl pyrophosphate synthetase I) (PRS-I) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • rCG27134, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • unnamed protein product [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Prps1 protein [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • phosphoribosyl pyrophosphate synthetase I [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • phosphoribosylpyrophosphate synthetase (PRPS1) precursor [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • phosphoribosylpyrophosphate synthetase [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10116 PHOSPHORIBOSYL PYROPHOSPHATE SYNTHETASE 1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Ribose-phosphate pyrophosphokinase I (Phosphoribosyl pyrophosphate synthetase I) (PRS-I) [nr-271106-contam.fasta]
  • Tax_Id=10116 Gene_Symbol=Prps1 Ribose-phosphate pyrophosphokinase 1 [rat-ipi-250309-contam.fasta]
  • Ribose-phosphate pyrophosphokinase 1 OS=Rattus norvegicus GN=Prps1 [011711_HMR.fasta]
    • Organism: Rattus norvegicus
    Length: 318 amino acids

    Gene Ontology:
    Cellular Component: soluble fraction [IDA]
    cytosol [UNKNOWN]
    protein complex [IDA]
    Biological Process: urate biosynthetic process [UNKNOWN]
    ribonucleoside monophosphate biosynthetic process [IEA]
    hypoxanthine biosynthetic process [UNKNOWN]
    purine nucleotide biosynthetic process [UNKNOWN]
    nucleotide biosynthetic process [IDA]
    ribose phosphate metabolic process [IDA]
    AMP biosynthetic process [IDA]
    nervous system development [UNKNOWN]
    nucleoside metabolic process [IEA]
    purine base metabolic process [UNKNOWN]
    organ regeneration [IEP]
    cellular biosynthetic process [IEA]
    Molecular Function: nucleotide binding [IEA]
    magnesium ion binding [IDA]
    ATP binding [UNKNOWN][IDA][ISS]
    AMP binding [IDA]
    protein homodimerization activity [UNKNOWN][ISS]
    sugar binding [IDA]
    ribose phosphate diphosphokinase activity [UNKNOWN][IDA][ISS]
    GDP binding [IDA]
    ADP binding [IDA]
    transferase activity [IEA]
    kinase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPNIKIFSGS SHQDLSQKIA DRLGLELGKV VTKKFSNQET CVEIGESVRG EDVYIVQSGC  60
   61 GEINDNLMEL LIMINACKIA SASRVTAVIP CFPYARQDKK DKSRAPISAK LVANMLSVAG 120
  121 ADHIITMDLH ASQIQGFFDI PVDNLYAEPA VLKWIRENIS EWRNCTIVSP DAGGAKRVTS 180
  181 IADRLNVDFA LIHKERKKAN EVDRMVLVGD VKDRVAILVD DMADTCGTIC HAADKLLSAG 240
  241 ATRVYAILTH GIFSGPAISR INNACFEAVV VTNTIPQEDK MKHCSKIQVI DISMILAEAI 300
  301 RRTHNGESVS YLFSHVPL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..318] PSI-BLAST 107.0 No description for 2h06A was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle