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Protein Overview: CAP-PB

General Information:
Name(s) found: CAP-PB / FBpp0087433 [FlyBase]
Description(s) found:
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  • gi|45551068|ref|NP_724913.2| CAP, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|45445608|gb|AAM68780.2| CAP, isoform B [Drosophila melanogaster] [NCBI NR]
  • The gene CAP is referred to in FlyBase by the symbol Dmel\CAP (CG18408, FBgn0033504). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:6156528..6194529. It has the cytological map location 46F9-47A1. Based on sequence similarity, it is predicted to have molecular function</span>: vinculin binding. The biological processes in which it is involved are not known. 23 alleles are reported. No phenotypic data is available. It has 17 annotated transcripts and 17 annotated polypeptides. [FlyBase]
  • (AAM68780) CG18408-PB [DrosMelano7227.FASTAC.txt]
  • CG18408-PB, isoform B [Drosophila melanogaster]gi|45551068|ref|NP_724913.2| CG18408-PB [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2R:join(6182364..6182471,6183247..6183299,6183374..6183552,6183940..6187773,6192129..6192435,6192493..6192607,6192977..6193183,6193243..6193475,6193650..6193818); ID=FBpp0087433; name=CAP-PB; parent=FBgn0033504,FBtr0088344; dbxref=GB_pro [fly-100309-contam.fasta]
  • CG18408-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CAP CG18408-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2R:join(6182364..6182471,6183247..6183299,6183374..6183552,6183940..6187773,6192129..6192435,6192493..6192607,6192977..6193183,6193243..6193475,6193650..6193818); ID=FBpp0087433; name=CAP-PB; parent=FBgn0033504,FBtr0088344; dbxref=GB_protein:AAM68780.1,FlyBase:FBpp0087433,FlyBase_Annotation_IDs:CG18408-PB,GB_protein:AAM68780.2,REFSEQ:NP_724913,GB_protein:AAM68780; MD5=6eebdafb2c7632193d6bcd883baaf651; length=1734; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2R:join(6182364..6182471,6183247..6183299,6183374..6183552,6183940..6187773,6192129..6192435,6192493..6192607,6192977..6193183,6193243..6193475,6193650..6193818); ID=FBpp0087433; name=CAP-PB; parent=FBgn0033504,FBtr0088344; dbxref=GB_protein:AAM68780.1,FlyBase:FBpp0087433,FlyBase_Annotation_IDs:CG18408-PB,GB_protein:AAM68780.2,REFSEQ:NP_724913,GB_protein:AAM68780; MD5=6eebdafb2c7632193d6bcd883baaf651; length=1734; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • CAP, isoform B OS=Drosophila melanogaster GN=CAP PE=4 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2R:join(6182364..6182471,6183247..6183299,6183374..6183552,6183940..6187773,6192129..6192435,6192493..6192607,6192977..6193183,6193243..6193475,6193650..6193818); ID=FBpp0087433; name=CAP-PB; parent=FBgn0033504,FBtr0088344; dbxref=GB_protein:AAM68780.1,FlyBase:FBpp0087433,FlyBase_Annotation_IDs:CG18408-PB,GB_protein:AAM68780.2,REFSEQ:NP_724913,GB_protein:AAM68780,FlyMine:FBpp0087433,modMine:FBpp0087433; MD5=6eebdafb2c7632193d6bcd883baaf651; length=1734; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2R:join(10294859..10294966,10295742..10295794,10295869..10296047,10296435..10300268,10304624..10304930,10304988..10305102,10305472..10305678,10305738..10305970,10306145..10306313); ID=FBpp0087433; name=CAP-PB; parent=FBgn0033504,FBtr0088344; dbxref=GB_protein:AAM68780.1,FlyBase:FBpp0087433,FlyBase_Annotation_IDs:CG18408-PB,GB_protein:AAM68780.2,REFSEQ:NP_724913,GB_protein:AAM68780,FlyMine:FBpp0087433,modMine:FBpp0087433; MD5=6eebdafb2c7632193d6bcd883baaf651; length=1734; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2R:join(10294859..10294966,10295742..10295794,10295869..10296047,10296435..10300268,10304624..10304930,10304988..10305102,10305472..10305678,10305738..10305970,10306145..10306313); ID=FBpp0087433; name=CAP-PB; parent=FBgn0033504,FBtr0088344; dbxref=GB_protein:AAM68780.1,FlyBase:FBpp0087433,FlyBase_Annotation_IDs:CG18408-PB,GB_protein:AAM68780.2,REFSEQ:NP_724913,GB_protein:AAM68780,FlyMine:FBpp0087433,modMine:FBpp0087433; MD5=6eebdafb2c7632193d6bcd883baaf651; length=1734; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of A0A0B4K7L3, CAP, isoform B OS=Drosophila melanogaster GN=CAP PE=1 SV=1 [DROME.fasta.20160308]
  • FBpp0087433 type=protein; loc=2R:join(10294859..10294966,10295742..10295794,10295869..10296047,10296435..10300268,10304624..10304930,10304988..10305102,10305472..10305678,10305738..10305970,10306145..10306313); ID=FBpp0087433; name=CAP-PB; parent=FBgn0033504,FBtr0088344; dbxref=GB_protein:AAM68780.1,FlyBase:FBpp0087433,FlyBase_Annotation_IDs:CG18408-PB,GB_protein:AAM68780.2,REFSEQ:NP_724913,GB_protein:AAM68780,FlyMine:FBpp0087433,modMine:FBpp0087433; MD5=6eebdafb2c7632193d6bcd883baaf651; length=1734; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2R:join(10294859..10294966,10295742..10295794,10295869..10296047,10296435..10300268,10304624..10304930,10304988..10305102,10305472..10305678,10305738..10305970,10306145..10306313); ID=FBpp0087433; name=CAP-PB; parent=FBgn0033504,FBtr0088344; dbxref=GB_protein:AAM68780.1,FlyBase:FBpp0087433,FlyBase_Annotation_IDs:CG18408-PB,GB_protein:AAM68780.2,REFSEQ:NP_724913,GB_protein:AAM68780,UniProt/TrEMBL:A1Z871,FlyMine:FBpp0087433,modMine:FBpp0087433; MD5=6eebdafb2c7632193d6bcd883baaf651; length=1734; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 1734 amino acids

    Gene Ontology:
    Cellular Component: focal adhesion [ISS]
    Biological Process: NONE FOUND
    Molecular Function: vinculin binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPNPIKSAQN SYKNQPGRIE NYTTGHSSVS EKEKKENLEQ SKLSPLYTEG NLSRALAKES  60
   61 GYTSDSNLVF RKKEVPVSSP LSPVEQKQAY KSLQAGGEPP LLGFRKPAPE KPREILEEFE 120
  121 FIQITPTLTK IRVSTKELEE EVEPVRKAAT PPPAPPPPPP PPPHQSLATS RDHKPVKMFS 180
  181 QLSKNLPSFI PLSKKQQVSQ QDDPPPRPPH RKSSCTKSTV RVLSSASKSR HEQCFQPPNG 240
  241 TAPGVSTITL RKVATSSCSR REPICRSKSA GAVSTLLQTL TATKETRLTR RVQQQQQQSR 300
  301 LRSSSPSRRP ARLLALRHSS RSPVAFGRSI SKERSFAEEK KRLENTLPAN RTNFEASTNI 360
  361 LRDPSLKSPQ EVREAVRSYA TSRSKSLPRL RHTTVSTTTR QTMCFPQVRP QTLLDCGTRS 420
  421 LRKSSSKTGK GQEKNGSNDS LPRSNSTFSI DSMVRQEIVP IAPPKTYVGK SRGSLSKALV 480
  481 PLQNSRSEGH VPRKRQSGKS TTKPPPPVTV HSYSESVREK TNFWNEYNAK QAMSLPQEYK 540
  541 FCPEDVCDFE SHTIQQPCIE DLVWKYEGKE QRPPKQVTVT DIARPQSPQL SQERRFSPTR 600
  601 EVRVPQISRE VRSPSRRRID SLRSKDKEQS LARASSLSSA DDRKRATPAP SNGLYQCGEL 660
  661 AHSATSLTHL ERHSPSCRYR NNCERFTELN RFYSTLERVG QLERATSSSS FHPLRKDAEL 720
  721 LDFDEWRRVR LHERAEKELQ YLVGKLRDDQ KQRDLHFRSK DVDSIKWRQE ADQSLIAKKK 780
  781 SVEDLRENFE QLNLLRQQQQ LQSEPVHRHW RRNTVADLAC SLEHQALAEP EMERHLDNDL 840
  841 VSTLSKDQIK KITQQLNEIY SGNRHAPAVE EQYVVTVEKG SRPNGLKVRC NSTISKDQLL 900
  901 GPVQRKRDEQ HSNQTLPRST RSQSPVVVAR ETRGAIAAKN AELTLTKPPD VPPRPKPTPS 960
  961 QEIKSKPPPK AEPKVEAREP AEDISQKIQY FEDRQFDEPP KTIYHAREDS SPDEAEVMRL1020
 1021 INQNMQERQR ARQLHHHQEL SNSLTDLSGV FGERPAARVN FHLHSPPDRP PDDTELISFG1080
 1081 NGSPDHGDGS LELYSDSYYR SRSLSPQSQV SACSSSYLQR VYTGEVRKMR QHFESIQQSG1140
 1141 EQSREPSNER RDFFGLSSLR RARSDPEMSA GSKDAPDTVT EAVSKEDVPR LTHKFELRAA1200
 1201 TPSPERGRKR LRSAQDRLMP HIDIISKTAA LKRELPIPVR SSPTRSVSSN SHCFERLRMR1260
 1261 YESPEPQTQS YLSTSHPDMR DVHDISPHLS ADWVAHKHPE PTKPKDLPKK PQRVVRASST1320
 1321 SPLRPARSQN HQLSSRLTSC MKDIFANQKF DPNKHRPKAR YVPDGAENGN QKSKDNGTLE1380
 1381 RLKKTAMVTF KDVNIHFKTP IRHEQRQNLS EEELAIRQAE HMQKLYHEER RRKYLQELQD1440
 1441 MNSRRHTDNF TPSQKSPIAL NRYDDFPTDV TLKSLVGPKT VARALFNFQG QTSKELSFRK1500
 1501 GDTIYIRRQI DANWYEGEHN AMIGLLPASY VEIVSRDGAR TPSKRPSEGQ ARAKYNFQAQ1560
 1561 SGIELSLNKG ELVTLTRRVD GNWFEGKIAN RKGIFPCSYV EVLTDIGAED IAARTTTVIT1620
 1621 SQSTTNLRPN LDVLRTNINN EFNTLTQNGA QPPNGILKET RTLHKTDALH VDTSSEPLAY1680
 1681 RALYKYRPQN SDELELLEGD VVHVLEKCDD GWFVGTSQRT GCFGTFPGNY VERA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..122] deduced N/A No confident structure predictions are available.
    2 View Details [123..210] deduced N/A No confident structure predictions are available.
    3 View Details [211..492] deduced N/A No confident structure predictions are available.
    4 View Details [493..662] MSA 3.134983 View MSA. No confident structure predictions are available.
    5 View Details [663..1401] FFAS03 1.15 Anthrax toxin lethal factor, N- and C-terminal domains; Anthrax toxin lethal factor, middle domain
    6 View Details [1402..1474] PSI-BLAST 16.69897 No description for 2h8hA was found.
    7 View Details [1475..1734] PSI-BLAST 33.69897 Growth factor receptor-bound protein 2 (GRB2), N- and C-terminal domains; Growth factor receptor-bound protein 2 (GRB2)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5
    Term Confidence Notes
  • hydrolase activity
    		•  0.397873089142268 bayes_pls_golite062009
    6 No functions predicted.
    7
    Term Confidence Notes
  • binding
    		•  1.07557226125735 bayes_pls_golite062009
  • protein binding
    		•  0.974282259959803 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle